Correlations between skin prick tests using commercial extracts and fresh foods, specific IgE, and food challenges

Allergy ◽  
1997 ◽  
Vol 52 (10) ◽  
pp. 1031-1035 ◽  
Author(s):  
F. Rancé ◽  
A. Juchet ◽  
F. Brémont ◽  
G. Dutau
Keyword(s):  
Specific Ige ◽  
Skin Prick Tests ◽  
Food Challenges ◽  
Fresh Foods

scholarly journals Chronic Milk-Dependent Food Protein-Induced Enterocolitis Syndrome in Children from West Pomerania Region

Nutrients ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 4137
Author(s):  
Karolina Bulsa ◽  
Małgorzata Standowicz ◽  
Elżbieta Baryła-Pankiewicz ◽  
Grażyna Czaja-Bulsa
Keyword(s):  
At Risk ◽  
Specific Ige ◽  
Food Protein ◽  
Milk Allergy ◽  
Intravenous Hydration ◽  
Ige Mediated ◽  
Skin Prick Tests ◽  
Food Challenges ◽  
Casein Hydrolysates ◽  
Food Sensitization

Characteristics of chronic milk-dependent food protein-induced enterocolitis syndrome (FPIES) in children from the region of Western Pomerania were studied. Prospectively, 55 children were diagnosed at a median of 2.2 months. The open food challenges (OFC), morphologies, milk-specific IgE (sIgE) (FEIA method, CAP system), and skin prick tests (SPTs) were examined. Vomiting and diarrhea escalated gradually but quickly led to growth retardation. Of the infants, 49% had BMI < 10 c, 20% BMI < 3 c; 25% had anemia, and 15% had hypoalbuminemia. During the OFCs we observed acute symptoms that appeared after 2–3 h: vomiting diarrhea and pallor. A total of 42% children required intravenous hydration. Casein hydrolysates or amino acids formulae (20%) were used in treatment. In 25% of children, SPT and milk sIgE were found, in 18%—other food SPTs, and in 14% allergy to other foods. A transition to IgE-dependent milk allergy was seen in 3 children. In the twelfth month of life, 62% of children had tolerance to milk, and in the twenty-fifth month—87%. Conclusions. Chronic milk-dependent FPIES resolves in most children. By the age of 2 children are at risk of multiple food sensitization, and those who have milk sIgE are at risk to transition to IgE-mediated milk allergy. Every OFC needs to be supervised due to possible severe reactions.

CORRELATION OF SERUM SPECIFIC IGE AND SKIN PRICK TESTS IN CHILDREN WITH RESPIRATORY ALLERGY

2011 ◽  
Author(s):  
Esen Demir ◽  
Levent Midyat ◽  
Figen Gulen ◽  
Gulhadiye Akbas ◽  
Sema Tanrıverdi ◽  
...  
Keyword(s):  
Specific Ige ◽  
Respiratory Allergy ◽  
Skin Prick Tests

scholarly journals Addressing Common Misconceptions in Food Allergy: A Review

Children ◽  
2021 ◽  
Vol 8 (6) ◽  
pp. 497
Author(s):  
Aikaterini Anagnostou
Keyword(s):  
Food Allergy ◽  
The United States ◽  
Specific Ige ◽  
Oral Immunotherapy ◽  
Food Allergies ◽  
Allergy Prevention ◽  
Diagnosis And Management ◽  
Skin Prick Tests ◽  
Food Specific Ige ◽  
Common Misconceptions

Background: Food allergies are common, affecting 1 in 13 school children in the United States and their prevalence is increasing. Many misconceptions exist with regards to food allergy prevention, diagnosis and management. Objective: The main objective of this review is to address misconceptions with regards to food allergies and discuss the optimal, evidence-based approach for patients who carry this diagnosis. Observations: Common misconceptions in terms of food allergy prevention include beliefs that breastfeeding and delayed introduction of allergenic foods prevent the development of food allergies. In terms of diagnosis, statements such as ‘larger skin prick tests or/and higher levels of food-specific IgE can predict the severity of food-induced allergic reactions’, or ‘Tryptase is always elevated in food-induced anaphylaxis’ are inaccurate. Additionally, egg allergy is not a contraindication for receiving the influenza vaccine, food-allergy related fatalities are rare and peanut oral immunotherapy, despite reported benefits, is not a cure for food allergies. Finally, not all infants with eczema will develop food allergies and epinephrine auto-injectors may unfortunately be both unavailable and underused in food-triggered anaphylaxis. Conclusions and relevance: Healthcare professionals must be familiar with recent evidence in the food allergy field and avoid common misunderstandings that may negatively affect prevention, diagnosis and management of this chronic disease.

Maternal Avoidance of Eggs, Cow's Milk, and Fish During Lactation: Effect on Allergic Manifestations, Skin-Prick Tests, and Specific IgE Antibodies in Children at Age 4 Years

PEDIATRICS ◽  
1992 ◽  
Vol 89 (4) ◽  
pp. 735-739
Author(s):  
Nele Sigurs ◽  
Gunnar Hattevig ◽  
Bengt Kjellman
Keyword(s):  
Specific Ige ◽  
Normal Diet ◽  
Cow’S Milk ◽  
Positive Skin ◽  
Ige Antibodies ◽  
Cow's Milk ◽  
Number Of Children ◽  
Specific Ige Antibodies ◽  
Skin Prick Tests ◽  
Allergic Manifestations

Two matched groups of children with a family history of atopy/allergy were observed from birth. In one group (n = 65) the mothers had a diet free from eggs, cow's milk, and fish during the first 3 months of lactation, whereas the mothers in the other group (n = 50) had a normal diet. Atopic/allergic manifestations, skin-prick tests, and specific IgE antibodies to egg white and cow's milk during the first 18 months of life have been reported previously. At 4 years of age the children underwent a clinical examination, skin-prick tests, and determination of specific IgE antibodies in serum against certain food and inhalant allergens. Both the cumulative incidence and the current prevalence of atopic dermatitis were significantly lower in the group of children whose mothers had adhered to a hypoallergenic diet during lactation, whereas all other atopic manifestations were similar. The number of children with positive skin-prick tests and specific IgE antibodies did not differ significantly, but the number of positive skin-prick tests and specific IgE antibody reactions in serum was significantly lower in the children of mothers adhering to the diet, indicating a milder degree of sensitization in these children.

Allergic rhinitis

2020 ◽  
pp. 4059-4066
Author(s):  
Stephen R. Durham ◽  
Hesham A. Saleh
Keyword(s):  
Allergic Rhinitis ◽  
Work Performance ◽  
Occupational Exposures ◽  
Specific Ige ◽  
Nasal Discharge ◽  
School Work ◽  
Tissue Eosinophilia ◽  
Skin Prick Tests

Allergic rhinitis affects more than 20% of the population of Westernized countries and has a significant impact on quality of life and school/work performance. Important environmental factors include tree and grass pollens (seasonal allergic rhinitis); house dust mite and domestic pets, most often cats (perennial allergic rhinitis); and a variety of occupational exposures (occupational rhinitis). Pathogenesis involves activation of type 2 (Th2) lymphocytes resulting in IgE antibody production and tissue eosinophilia. Immediate symptoms (itching, sneezing, and watery nasal discharge) result from allergen cross-linking adjacent IgE molecules on the surface of mast cells in the nasal mucosa, resulting in the release of histamine and tryptase, and generation of bradykinin. Diagnosis is usually straightforward and based on the history, examination, and (when indicated) the results of skin prick tests and/or serum allergen-specific IgE levels.

Evaluation of Dermatophagoides pteronyssinus (Trouessart) and D. farinae Hughes (Acari: Pyroglyphidae) sensitivity in patients with allergic rhinitis: a comparative study

2018 ◽  
Vol 23 (2) ◽  
pp. 206
Author(s):  
Erhan ZEYTUN ◽  
Salih DOĞAN ◽  
Edhem Ünver ◽  
Fatih ÖZÇÜÇEK
Keyword(s):  
Allergic Rhinitis ◽  
Comparative Study ◽  
Clinical Assessment ◽  
Serum Levels ◽  
Specific Ige ◽  
Dermatophagoides Pteronyssinus ◽  
Total Ige ◽  
Serologic Tests ◽  
Stereo Microscope ◽  
Skin Prick Tests

This study was conducted to determine the sensitivity to Dermatophagoides pteronyssinus (Trouessart) and D. farinae Hughes with skin prick tests (SPT) and serologic tests in patients with allergic rhinitis (AR), and to specifically search for those mites in homes of patients. A total of 51 participants, (23 patients and 28 controls) were utilized. Skin-prick tests with D. pteronyssinus and D. farinae allergens were performed on all participants, and serum levels of allergen-specific lgE and total IgE were also measured. Dust samples were collected from homes of all participants and examined under a stereo microscope. 977 D. pteronyssinus (mean 44.4/g) and 24 D. farinae (mean 4.0/g) were isolated from the homes of patients, whereas 35 D. pteronyssinus (mean 4.4/g), and four D. farinae (mean 2.0/g) were isolated from the homes of the controls. Patients with D. pteronyssinus in their homes had 95.5% sensitivity to the species according to SPT and 27.3 according to IgE. Patients with D. farinae in their homes had 83.3% sensitivity to the species according to SPT, and 50% according to IgE. Dermatophagoides pteronyssinus sensitivity in the controls was detected as 12.5% according to SPT; however, D. farinae sensitivity was not detected according to both SPT and mite-specific IgE. Differences between patients and controls utilizing SPT results was statistically significant, but not when using mite-specific IgE results. As a result, it was determined that patients with AR in Erzincan province were sensitized to D. pteronyssinus and D. farinae, and that their homes contained those species. It may be helpful to consider these findings in clinical assessment of patients with AR, and also in treatment utilizing immunotherapy techniques.

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