Event-related potential correlates of functional hearing loss: Reduced P3 amplitude with preserved Nl and N2 components in a unilateral case

1996 ◽  
Vol 50 (2) ◽  
pp. 85-88 ◽  
Author(s):  
MASATO FUKUDA ◽  
AKINOBU HATA ◽  
SHIN-ICHI NIWA ◽  
KEN-ICHI HIRAMATSU ◽  
MASAFUMI YOKOKOJI ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Event Related Potential ◽  
Unilateral Case ◽  
P3 Amplitude

scholarly journals Event-Related Potential Evidence of Enhanced Visual Processing in Auditory-Associated Cortex in Adults with Hearing Loss

2020 ◽  
Vol 25 (5) ◽  
pp. 237-248
Author(s):  
Maojin Liang ◽  
Jiahao Liu ◽  
Yuexin Cai ◽  
Fei Zhao ◽  
Suijun Chen ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Visual Processing ◽  
Event Related Potentials ◽  
Event Related Potential ◽  
Occipital Area ◽  
Mapping Analysis ◽  
Related Potentials ◽  
The Difference ◽  
The Right ◽  
Frontotemporal Area

Objective: The present study investigated the characteristics of visual processing in the auditory-associated cortex in adults with hearing loss using event-related potentials. Methods: Ten subjects with bilateral postlingual hearing loss were recruited. Ten age- and sex-matched normal-hearing subjects were included as controls. Visual (“sound” and “non-sound” photos)-evoked potentials were performed. The P170 response in the occipital area as well as N1 and N2 responses in FC3 and FC4 were analyzed. Results: Adults with hearing loss had higher P170 amplitudes, significantly higher N2 amplitudes, and shorter N2 latency in response to “sound” and “non-sound” photo stimuli at both FC3 and FC4, with the exception of the N2 amplitude which responded to “sound” photo stimuli at FC3. Further topographic mapping analysis revealed that patients had a large difference in response to “sound” and “non-sound” photos in the right frontotemporal area, starting from approximately 200 to 400 ms. Localization of source showed the difference to be located in the middle frontal gyrus region (BA10) at around 266 ms. Conclusions: The significantly stronger responses to visual stimuli indicate enhanced visual processing in the auditory-associated cortex in adults with hearing loss, which may be attributed to cortical visual reorganization involving the right frontotemporal cortex.

Changes in Auditory P3 Event-related Potential in Schizophrenia and Depression

1987 ◽  
Vol 150 (2) ◽  
pp. 154-160 ◽  
Author(s):  
D. H. R. Blackwood ◽  
L. J. Whalley ◽  
J. E. Christie ◽  
I. M. Blackburn ◽  
D. M. St Clair ◽  
...  
Keyword(s):  
Event Related Potentials ◽  
Event Related Potential ◽  
Psychotic Symptoms ◽  
Auditory Information ◽  
Depressed Patients ◽  
Depressed Group ◽  
Schizophrenic Patients ◽  
Related Potentials ◽  
Schizophrenic Group ◽  
P3 Amplitude

Event-related potentials during a two-tone discrimination task were recorded in 24 schizophrenic patients, 16 depressed patients and 59 control subjects. Recordings were made when patients were medication-free. Fourteen schizophrenic and 13 depressed patients were retested at 1 and 4 weeks after the start of treatment, and 13 schizophrenic patients were also tested between 6 and 24 months after the initial recordings. In the schizophrenic group, the P3 latency was significantly prolonged compared with that in the control and the depressed groups, and remained unchanged both after 4 weeks treatment with therapeutic doses of neuroleptic drugs and at long-term follow-up. In the depressed group, the P3 latency did not differ from that of controls. P3 amplitude by contrast was reduced in both the acutely depressed and schizophrenic groups and following treatment became normal in the depressed group but remained reduced in the schizophrenic group. It is suggested that a prolonged P3 latency and reduced P3 amplitude indicate an impairment of auditory information processing in some patients with schizophrenia which is independent of the presence of acute psychotic symptoms and is not influenced by neuroleptic medication.

scholarly journals Cortical Auditory Evoked Potentials in Cognitive Impairment and Their Relevance to Hearing Loss: A Systematic Review Highlighting the Evidence Gap

2021 ◽  
Vol 15 ◽  
Author(s):  
Hanne Gommeren ◽  
Joyce Bosmans ◽  
Emilie Cardon ◽  
Griet Mertens ◽  
Patrick Cras ◽  
...  
Keyword(s):  
Systematic Review ◽  
Hearing Loss ◽  
Cognitive Impairment ◽  
Cognitive Decline ◽  
Auditory Processing ◽  
Auditory Evoked Potentials ◽  
Event Related Potential ◽  
Auditory Evoked Potential ◽  
Publication Date ◽  
Reference List

Background: Alzheimer’s disease (AD) is the most prevalent cause of dementia which affects a growing number of people worldwide. Early identification of people at risk to develop AD should be prioritized. Hearing loss is considered an independent potentially modifiable risk factor for accelerated cognitive decline and dementia in older adults. The main outcome of interest of this review is the alteration of Cortical Auditory Evoked Potential (CAEP) morphology in an AD or mild cognitive impairment (MCI) population with and without hearing loss.Methods: Two investigators independently and systematically searched publications regarding auditory processing on a cortical level in people with cognitive impairment (MCI or AD) with and without hearing loss. Only articles which mentioned at least one auditory elicited event-related potential (ERP) component and that were written in English or Dutch were included. Animal studies were excluded. No restrictions were imposed regarding publication date. The reference list of potential sources were screened for additional articles.Results: This systematic review found no eligible articles that met all inclusion criteria. Therefore, no results were included, resulting in an empty systematic review.Conclusion: In general, dysfunction – being either from cognitive or auditory origin – reduces CAEP amplitudes and prolongs latencies. Therefore, CAEPs may be a prognostic indicator in the early stages of cognitive decline. However, it remains unclear which CAEP component alteration is due to cognitive impairment, and which is due to hearing loss (or even both). In addition, vestibular dysfunction – associated with hearing loss, cognitive impairment and AD – may also alter CAEP responses. Further CAEP studies are warranted, integrating cognitive, hearing, and vestibular evaluations.

scholarly journals A meta-analysis of the P3 amplitude in tasks requiring deception in legal and social contexts

2017 ◽  
Author(s):  
Anja Leue ◽  
André Beauducel
Keyword(s):  
Cognitive Processes ◽  
Meta Analysis ◽  
A Priori ◽  
Large Population ◽  
Mental Effort ◽  
Social Contexts ◽  
Event Related Potential ◽  
Show Evidence ◽  
P3 Amplitude ◽  
Legal Contexts

In deception tasks the parietal P3 amplitude of the event-related potential indicates either recognition of salient stimuli (larger P3 following salient information) or mental effort (negative or smaller P3 following demanding information). This meta-analysis (k = 77) investigated both cognitive processes by means of conceptual and methodological a-priori moderators (study design, pre-task scenario, context of deception tasks, and P3 quantification). Within-subjects designs show evidence of the underlying cognitive processes, between-subjects designs allow for comparisons of cognitive processes in culprits vs. innocents. Deception in legal contexts results in almost twice as large population effect sizes (delta) than deception in social contexts. Deception in legal contexts supports the salience hypothesis (largest delta), deception in social contexts suggests a combination of salience recognition and mental effort (smaller delta), and active lying requires more mental effort (negative delta). Counter-measure techniques in 3-stimulus protocols reduce the discriminability of concealed vs. truthful P3 amplitudes.

scholarly journals Rhythmic Training Improves Temporal Anticipation and Adaptation Abilities in Children With Hearing Loss During Verbal Interaction

2019 ◽  
Vol 62 (9) ◽  
pp. 3234-3247 ◽  
Author(s):  
Céline Hidalgo ◽  
Jacques Pesnot-Lerousseau ◽  
Patrick Marquis ◽  
Stéphane Roman ◽  
Daniele Schön
Keyword(s):  
Hearing Loss ◽  
Hearing Aids ◽  
Speech Rate ◽  
Normal Hearing ◽  
Event Related Potential ◽  
Auditory Training ◽  
Temporal Adaptation ◽  
Accurate Performance ◽  
Speech Interaction ◽  
Children With Hearing Loss

Purpose In this study, we investigate temporal adaptation capacities of children with normal hearing and children with cochlear implants and/or hearing aids during verbal exchange. We also address the question of the efficiency of a rhythmic training on temporal adaptation during speech interaction in children with hearing loss. Method We recorded electroencephalogram data in children while they named pictures delivered on a screen, in alternation with a virtual partner. We manipulated the virtual partner's speech rate (fast vs. slow) and the regularity of alternation (regular vs. irregular). The group of children with normal hearing was tested once, and the group of children with hearing loss was tested twice: once after 30 min of auditory training and once after 30 min of rhythmic training. Results Both groups of children adjusted their speech rate to that of the virtual partner and were sensitive to the regularity of alternation with a less accurate performance following irregular turns. Moreover, irregular turns elicited a negative event-related potential in both groups, showing a detection of temporal deviancy. Notably, the amplitude of this negative component positively correlated with accuracy in the alternation task. In children with hearing loss, the effect was more pronounced and long-lasting following rhythmic training compared with auditory training. Conclusion These results are discussed in terms of temporal adaptation abilities in speech interaction and suggest the use of rhythmic training to improve these skills of children with hearing loss.

Genetic Contribution to the P3 in Young and Middle-Aged Adults

2007 ◽  
Vol 10 (2) ◽  
pp. 335-347 ◽  
Author(s):  
Dirk J. A. Smit ◽  
Danielle Posthuma ◽  
Dorret I. Boomsma ◽  
Eco J.C. de Geus
Keyword(s):  
Event Related Potential ◽  
Oddball Paradigm ◽  
Middle Aged ◽  
Cohort Differences ◽  
P3 Amplitude ◽  
Middle Aged Adult ◽  
Adolescent Twins ◽  
Middle Aged Adults ◽  
Genetic Contributions ◽  
Potential Waveform

AbstractPrevious studies in young and adolescent twins suggested substantial genetic contributions to the amplitude and latency of the P3 evoked by targets in an oddball paradigm. Here we examined whether these findings can be generalized to adult samples. A total of 651 twins and siblings from 292 families participated in a visual oddball task. In half of the subjects the age centered around 26 (young adult cohort), in the other half the age centered around 49 (middle-aged adult cohort). P3 peak amplitude and latency were scored for 3 midline leads Pz, Cz, and Fz. No cohort differences in heritability were found. P3 amplitude (∼50%) and latency (∼45%) were moderately heritable for the 3 leads. A single genetic factor influenced latency at all electrodes, suggesting a single P3 timing mechanism. Specific genetic factors influenced amplitude at each lead, suggesting local modulation of the P3 once triggered. Genetic analysis of the full event-related potential waveform showed that P3 heritability barely changes from about 100 ms before to 100 ms after the peak. Age differences are restricted to differences in means and variances, but the proportion of genetic variance as part of the total variance of midline P3 amplitude and latency does not change from young to middle-aged adulthood.

Startle-elicited Event-Related Potentials to Affective Stimuli are Associated with Recent Illicit Opioid use among Patients Receiving Opioid Agonist Treatment

2021 ◽  
pp. 155005942110701
Author(s):  
Joshua BB Garfield ◽  
Ali Cheetham ◽  
Nicholas B Allen ◽  
Paul G Sanfilippo ◽  
Dan I Lubman
Keyword(s):  
Event Related Potentials ◽  
Event Related Potential ◽  
Control Group ◽  
Opioid Use ◽  
Opioid Agonist ◽  
Opioid Agonist Treatment ◽  
Affective Stimuli ◽  
Related Potentials ◽  
P3 Amplitude ◽  
Illicit Opioid Use

Opioid use disorder (OUD) has been linked to exaggerated attentional, affective, and arousal responses to opioid-related stimuli, as well as altered responses to other affective (eg, naturally rewarding or aversive) stimuli, particularly blunted responses to pleasant/rewarding stimuli. Both exaggerated responses to drug-related stimuli and reduced response to pleasant stimuli may influence the course of OUD and its treatment, however interpretation of studies thus far is limited by methodological issues. In the present study, we examined subjective ratings, and attenuation of the P3 component of the acoustic startle-evoked event-related potential (as a measure of attention), while viewing neutral, pleasant, unpleasant, and drug-related images. Participants prescribed opioid agonist treatment (OAT) for OUD (n = 82) were compared to a carefully-matched control group (n = 33) and to recently-abstinent participants with OUD (n = 22). Relative to controls, participants prescribed OAT gave higher positive valence ratings of drug images, and blunted valence responses to other affective images, but groups did not differ in terms of arousal ratings or P3 amplitude. Within the OAT group, linear modeling of associations between frequency of recent illicit opioid use and startle P3 amplitude found an association between increased recent illicit opioid use and reduced attention to pleasant, relative to unpleasant, images. The latter finding may have implications for interventions targeting cognitive biases in people with substance use disorder. In particular, they suggest that enhancing attention to pleasant stimuli may be as, if not more important, than the typical approach of trying to reduce attentional bias to drug-related stimuli.

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