Maternal mental disorders and pregnancy outcomes: A clinical study in a Japanese population

2011 ◽  
Vol 37 (10) ◽  
pp. 1283-1289 ◽  
Author(s):  
Masae Hironaka ◽  
Tomomi Kotani ◽  
Seiji Sumigama ◽  
Hiroyuki Tsuda ◽  
Yukio Mano ◽  
...  
Keyword(s):  
Clinical Study ◽  
Mental Disorders ◽  
Pregnancy Outcomes ◽  
Japanese Population

scholarly journals Pregnancy Experience: Nonclinical Studies and Pregnancy Outcomes in the Daclizumab Clinical Study Program

2016 ◽  
Vol 5 (2) ◽  
pp. 169-182 ◽  
Author(s):  
Ralf Gold ◽  
Dusan Stefoski ◽  
Krzysztof Selmaj ◽  
Eva Havrdova ◽  
Christopher Hurst ◽  
...  
Keyword(s):  
Clinical Study ◽  
Pregnancy Outcomes ◽  
Study Program

β-Angles of hips with femoroacetabular impingement versus asymptomatic normal hips in a Japanese population: A CT-based observational clinical study

2020 ◽  
Vol 25 (2) ◽  
pp. 261-266
Author(s):  
Tomohiro Mimura ◽  
Kanji Mori ◽  
Noriaki Okumura ◽  
Kosuke Kumagai ◽  
Tsutomu Maeda ◽  
...  
Keyword(s):  
Clinical Study ◽  
Femoroacetabular Impingement ◽  
Japanese Population

scholarly journals Serum uromodulin is a novel predictive marker of renal function in the Japanese population

2020 ◽  
Author(s):  
Ryosuke Usui ◽  
Tetsuya Ogawa ◽  
Hideo Takahashi ◽  
Chihiro Iwasaki ◽  
Minako Koike ◽  
...  
Keyword(s):  
Clinical Study ◽  
Kidney Function ◽  
Cystatin C ◽  
Japanese Population ◽  
Estimated Glomerular Filtration Rate ◽  
Predictive Marker ◽  
Enzyme Linked Immunosorbent Assay ◽  
Serum Concentrations ◽  
Specific Enzyme ◽  
The Mean

Abstract Background Uromodulin, also known as Tamm-Horsfall protein, is the most abundant protein in urine. It has recently been reported that uromodulin exists in a small amount in blood and that its concentration correlates with the estimated glomerular filtration rate (eGFR). However, its clinical significance has not been clarified and there are no relevant data for the Japanese population. Method First, we generated anti-human uromodulin mouse monoclonal antibodies and established a specific enzyme-linked immunosorbent assay for uromodulin. We then performed an observational clinical study to determine if there was a correlation between serum uromodulin concentration and estimates of kidney function and whether the serum uromodulin value could be a biomarker in clinical nephrology. The clinical study included 308 patients with and without chronic kidney disease and healthy volunteers. Serum concentrations of creatinine, cystatin C, and uromodulin were measured and correlations were sought between the eGFR calculated from the creatinine and cystatin C levels and the serum uromodulin concentration. Results There was a good correlation between the serum uromodulin concentration and the eGFR value calculated from the creatinine (r=0.76) and cystatin C (r=0.79) levels. The mean serum uromodulin level in the group with an eGFR >90 mL/min/1.73 m 2 calculated using cystatin C was significantly higher than that in the group with an eGFR of 80–89 mL/min/1.73 m 2 . Conclusions The serum uromodulin measurement could be a useful biomarker for identification of patients with early deterioration of kidney function.

The Clinical Study of Mental Disorders

1926 ◽  
Vol 72 (S298) ◽  
pp. 1-79 ◽  
Author(s):  
J. R. Lord
Keyword(s):  
Clinical Study ◽  
Mental Disorders ◽  
Signal Recognition ◽  
The Future ◽  
Royal Charter

Now that our Association, by a gracious act of our Sovereign, has been granted a Royal Charter—a signal recognition of its achievements and of the humane principles and aspirations of which it is an expression; a change, too, which is emblematic of the growth of its activities and influence—it is not inappropriate that I should address you on some aspects of the practice of psychiatry, especially in regard to possibilities and lines of progress in the future, and as to how the Association might better assist their materialization. The aspect I wish particularly to dwell upon is that which is the title of my address.

scholarly journals Prof. E. Kraepelin. Psychiatry. Textbook for students and doctors. Per. from the 5th German edition. 2 part. St. Petersburg. 1898. Price 5 rubles

2020 ◽  
Vol VII (1) ◽  
pp. 177-178
Author(s):  
B. I. Vorotynskiy
Keyword(s):  
Mental Illness ◽  
Clinical Study ◽  
Mental Disorders ◽  
Russian Translation ◽  
Main Attention ◽  
German Edition

In the preface to the fifth (last) German edition of his manual, the author points out that in this edition his textbook has undergone significant and substantial changes, representing the last breakthrough transition from a symptomatological way of presenting a clinical study. In view of this, the author, when presenting, pays the main attention to the causes, course and outcome of mental disorders, pushing back into the background the meaning of external signs of mental illness. Since the Russian translation is delivered from the last German edition, it is likely to carry all the features of this edition, indicated by the author in the preface.

scholarly journals Abortion, substance abuse and mental health in early adulthood: Thirteen-year longitudinal evidence from the United States

2016 ◽  
Vol 4 ◽  
pp. 205031211666599 ◽  
Author(s):  
Donald Paul Sullins
Keyword(s):  
Mental Health ◽  
United States ◽  
Mental Disorders ◽  
Confidence Interval ◽  
Pregnancy Outcomes ◽  
Pregnancy Loss ◽  
Early Adulthood ◽  
The United States ◽  
Mental Health Disorder ◽  
Increased Risk

Objective: To examine the links between pregnancy outcomes (birth, abortion, or involuntary pregnancy loss) and mental health outcomes for US women during the transition into adulthood to determine the extent of increased risk, if any, associated with exposure to induced abortion. Method: Panel data on pregnancy history and mental health history for a nationally representative cohort of 8005 women at (average) ages 15, 22, and 28 years from the National Longitudinal Study of Adolescent to Adult Health were examined for risk of depression, anxiety, suicidal ideation, alcohol abuse, drug abuse, cannabis abuse, and nicotine dependence by pregnancy outcome (birth, abortion, and involuntary pregnancy loss). Risk ratios were estimated for time-dynamic outcomes from population-averaged longitudinal logistic and Poisson regression models. Results: After extensive adjustment for confounding, other pregnancy outcomes, and sociodemographic differences, abortion was consistently associated with increased risk of mental health disorder. Overall risk was elevated 45% (risk ratio, 1.45; 95% confidence interval, 1.30–1.62; p < 0.0001). Risk of mental health disorder with pregnancy loss was mixed, but also elevated 24% (risk ratio, 1.24; 95% confidence interval, 1.13–1.37; p < 0.0001) overall. Birth was weakly associated with reduced mental disorders. One-eleventh (8.7%; 95% confidence interval, 6.0–11.3) of the prevalence of mental disorders examined over the period were attributable to abortion. Conclusion: Evidence from the United States confirms previous findings from Norway and New Zealand that, unlike other pregnancy outcomes, abortion is consistently associated with a moderate increase in risk of mental health disorders during late adolescence and early adulthood.

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