Which people with Type 2 diabetes achieve good control of intermediate outcomes? Population database study in a UK region

Background: The aim of the study was to compare the hemoglobin levels among normal controls (patients) and patients of TypeII diabetes with HbA1c levels below 7 % & above 7 %.and secondly to identify the undetected cases of anemia in TypeII diabetes. Materials & Methods - 50 patients of type 2 diabetes mellitus with their glycosylated hemoglobin levels less than 7 %, 50 patients of type 2 diabetes mellitus with their glycosylated hemoglobin levels more than 7 % attending the Medicine outpatient department of Subharti Medical College and Hospital will be the subjects for the study.50 age and sex matched controls will be selected randomly from Subharti Medical College and Hospital. Informed written consent will be taken from all the subjects. The study will be conducted from January 2016 to January. Result - We studied 50 cases with HbA1C>7(poor control),50 cases with HbA1C 5.6 to7 (good control) and 50 controls with HbA1C ≤5.6, we observed in cases with HbA1C>7 (poorly control) ,the mean HbA1C is 9.9±2 and mean Hb is 9.8±1.3 as compared to cases with HbA1C 5.6 to 7(good control) where mean HbA1C is 6±0.4 and Hb is 13±0.5,this clearly indicates that in cases HbA1C is more Hb levels are low and when HbA1C is less Hb levels are higher. Conclusion - In the present study we found negative correlation between HbA1c & Hb levels. As the value of HbA1c increases, as in cases of HbA1c >7(poor diabetic control), we found low Hb levels as compared to the cases with HbA1c <7(5.6-7) (good control).

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987-P: Comparative Cardiovascular (CV) Effectiveness of SGLT2 Inhibitors (SGLT2i) and GLP-1 Receptor Agonists (GLP-1 RA) in Patients with Type 2 Diabetes Mellitus (T2DM): A Large National Database Study

Diabetes ◽

10.2337/db21-987-p ◽

2021 ◽

Vol 70 (Supplement 1) ◽

pp. 987-P

Author(s):

OMAR A. ALABER ◽

APOORVA K. CHANDAR ◽

AMITOJ SINGH ◽

AIMAN SMER ◽

NIVEDITHA MANIVANNAN ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Sglt2 Inhibitors ◽

National Database ◽

Database Study ◽

Receptor Agonists ◽

Large National Database

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Changes in HbA1c, body weight, and systolic blood pressure in type 2 diabetes patients initiating dapagliflozin therapy: a primary care database study

Diabetes Metabolic Syndrome and Obesity Targets and Therapy ◽

10.2147/dmso.s116243 ◽

2016 ◽

Vol Volume 9 ◽

pp. 337-345 ◽

Cited By ~ 11

Author(s):

Markus Scheerer ◽

Roland Rist ◽

Orm Proske ◽

Annika Meng ◽

Karel Kostev

Keyword(s):

Blood Pressure ◽

Type 2 Diabetes ◽

Primary Care ◽

Body Weight ◽

Systolic Blood Pressure ◽

Primary Care Database ◽

Database Study ◽

Care Database ◽

Diabetes Patients

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Direct medical costs of type 2 diabetes mellitus in the Philippines: findings from two hospital databases and physician surveys

BMJ Open ◽

10.1136/bmjopen-2021-049737 ◽

2021 ◽

Vol 11 (10) ◽

pp. e049737

Author(s):

Cecilia Jimeno ◽

Rosa Allyn Sy ◽

Pepito De La Pena ◽

Chritopher Cipriano ◽

Rima Tan ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Medical Cost ◽

Outpatient Care ◽

Good Control ◽

The Philippines ◽

Poor Control ◽

Control Range

ObjectiveTo estimate the annual direct medical cost of type 2 diabetes mellitus (T2DM) in hospitals and outpatient care clinics from a healthcare payer perspective in the Philippines.Design and participants(1) A review of electronic hospital records of people with T2DM in two tertiary hospitals—Ospital ng Makati (OsMak) and National Kidney and Transplant Institute (NKTI) and (2) a cross-sectional survey with 50 physicians providing outpatient care for people with T2DM.SettingPrimary, secondary and tertiary healthcare facilities in Metro Manila.Outcome measuresCost of managing T2DM and its related complications in US dollars (USD) in 2016.ResultsA total of 1023 and 1378 people were identified in OsMak and NKTI, with a complication rate of 66% and 74%, respectively. In both institutions, the average annual cost per person was higher if individuals were diagnosed with any complication (NKTI: US$3226 vs US$2242 and OsMak: US$621 vs US$127). Poor diabetes control was estimated to incur higher per person cost than good control in both public outpatient care (poor control, range: US$727 to US$2463 vs good control, range: US$614 to US$1520) and private outpatient care (poor control, range: US$848 to US$2507 vs good control, range: US$807 to US$1603).ConclusionThe results highlight the high direct medical cost resulting from poor diabetes control and the opportunity for cost reduction by improving control and preventing its complications.

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Type 2 Diabetes Mellitus And Vitamin C

Journal of Bahria University Medical and Dental College ◽

10.51985/jbumdc2019014 ◽

2019 ◽

Vol 09 (03) ◽

pp. 232-236

Author(s):

Shabzain Ishrat ◽

Talea Hoor ◽

Mohammed Sajid Abbas Jaffri

Keyword(s):

Oxidative Stress ◽

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Vitamin C ◽

Good Control ◽

Type 2 Dm ◽

Vitamin C Supplementation ◽

Antioxidant Supplements

Type 2 diabetes mellitus (DM) is a chronic disease which deteriorates the quality of life with time. Type 2 DM accounts for more than 90% cases of diabetes mellitus as compared to other types of this disease. There is significant oxidative stress in type 2 DM which plays an important role in the pathogenesis of disease. In order to combat this oxidative stress antioxidant supplements have to be added as add on therapy along with treatment of type 2 DM. Vitamin C is the safest antioxidant which plays significant role in diminishing the oxidative stress. The vitamin C supplementation have good control of FBS and HbA1c and therefore helps in achieving better glycemic control along with prevention of lipid abnormalities.

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Calculated Daily Insulin Dosages Overestimate Prescribed Insulin Doses in Type 2 Diabetes: A Primary Care Database Study

Journal of Diabetes Science and Technology ◽

10.1177/1932296816676187 ◽

2016 ◽

Vol 11 (3) ◽

pp. 597-601 ◽

Cited By ~ 1

Author(s):

Karel Kostev ◽

Wolfgang Rathmann

Keyword(s):

Type 2 Diabetes ◽

Primary Care ◽

Primary Care Database ◽

Database Study ◽

Daily Insulin ◽

Care Database

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Infant milk-feeding practices and diabetes outcomes in offspring: a systematic review

American Journal of Clinical Nutrition ◽

10.1093/ajcn/nqy311 ◽

2019 ◽

Vol 109 (Supplement_1) ◽

pp. 817S-837S ◽

Cited By ~ 4

Author(s):

Darcy Güngör ◽

Perrine Nadaud ◽

Concetta C LaPergola ◽

Carol Dreibelbis ◽

Yat Ping Wong ◽

...

Keyword(s):

Systematic Review ◽

Type 2 Diabetes ◽

Human Milk ◽

Systematic Reviews ◽

Limited Evidence ◽

Diabetes Outcomes ◽

Intermediate Outcomes ◽

Milk Feeding

ABSTRACTBackgroundDuring the Pregnancy and Birth to 24 Months Project, the US Departments of Agriculture and Health and Human Services initiated a review of evidence on diet and health in these populations.ObjectivesThe aim of these systematic reviews was to examine the relation of 1) never versus ever feeding human milk, 2) shorter versus longer durations of any human milk feeding, 3) shorter versus longer durations of exclusive human milk feeding, and 4) feeding a lower versus higher intensity of human milk to mixed-fed infants with type 1 and type 2 diabetes in offspring.MethodsThe Nutrition Evidence Systematic Review team conducted systematic reviews with external experts. We searched CINAHL, Cochrane, Embase, and PubMed for articles published January 1980–March 2016, dual-screened the results according to predetermined criteria, extracted data from and assessed the risk of bias for each included study, qualitatively synthesized the evidence, developed conclusion statements, and graded the strength of the evidence.ResultsThe 4 systematic reviews included 21, 37, 18, and 1 articles, respectively. Observational evidence suggests that never versus ever feeding human milk (limited evidence) and shorter versus longer durations of any (moderate evidence) and exclusive (limited evidence) human milk feeding are associated with higher type 1 diabetes risk. Insufficient evidence examined type 2 diabetes. Limited evidence suggests that the durations of any and exclusive human milk feeding are not associated with intermediate outcomes (e.g., fasting glucose, insulin resistance) during childhood.ConclusionsLimited to moderate evidence suggests that feeding less or no human milk is associated with higher risk of type 1 diabetes in offspring. Limited evidence suggests no associations between the durations of any and exclusive human milk feeding and intermediate diabetes outcomes in children. Additional research is needed on infant milk-feeding practices and type 2 diabetes and intermediate outcomes in US populations, which may have distinct metabolic risk.

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