An Electrophysiological Study of Semantic Processing in Young and Middle-Aged Academics

1992 ◽  
Vol 29 (1) ◽  
pp. 38-54 ◽  
Author(s):  
Thomas C. Gunter ◽  
Janet L. Jackson ◽  
Gijsbertus Mulder
Keyword(s):  
Semantic Processing ◽  
Electrophysiological Study ◽  
Middle Aged

scholarly journals Conduction disorders as the first hallmark of isolated cardiac sarcoidosis in a highly active individual: a case report

2021 ◽  
Author(s):  
Silvia Muccioli ◽  
Stefano Albani ◽  
Barbara Mabritto ◽  
Giuseppe Musumeci
Keyword(s):  
Corticosteroid Therapy ◽  
Cardiac Sarcoidosis ◽  
Multimodality Imaging ◽  
Electrophysiological Study ◽  
Cardiac Conduction ◽  
Moderate Physical Activity ◽  
Middle Aged ◽  
High Intensity Training ◽  
Highly Active ◽  
Active Individual

Abstract Background Cardiac sarcoidosis (CS) is an inflammatory disease with various clinical presentations depending on the extension of cardiac involvement. The disease is often clinically silent, therefore diagnosis is challenging. Case summary We discuss the case of a middle-aged highly active individual presenting with an occasional finding of low heart rate during self-monitoring. The electrocardiogram shows a Mobitz 2 heart block; thanks to multimodality imaging CS was diagnosed and corticosteroid therapy improved cardiac conduction. Discussion To our knowledge this is one of the first documented cases of occasional, early finding of CS in a middle-aged highly active individual who presented with cardiac conduction involvement. Despite the very early diagnosis, multimodality imaging suggested an advanced disease with no edema detection at the CMR. Nevertheless, prompt corticosteroid therapy was able to improve clinical conduction. Although non-sustained ventricular arrhythmias were detected, electrophysiological study allowed to discharge the patient safely without implantable cardioverter defibrillator implantation. Light-to moderate physical activity was allowed at mid-term follow up. A multidisciplinary evaluation should be considered to resume a high intensity training.

scholarly journals Association of abnormal semantic processing with delusion-like ideation in frequent cannabis users: an electrophysiological study

2012 ◽  
Vol 225 (1) ◽  
pp. 95-104 ◽  
Author(s):  
Michael Kiang ◽  
Bruce K. Christensen ◽  
David L. Streiner ◽  
Carolyn Roy ◽  
Iulia Patriciu ◽  
...  
Keyword(s):  
Semantic Processing ◽  
Electrophysiological Study

scholarly journals A Retrospective Analysis of Pain Etiology in Middle-Aged Patients with Peripheral Neuropathy

Medicina ◽  
2021 ◽  
Vol 57 (8) ◽  
pp. 787
Author(s):  
Anna K. Szewczyk ◽  
Anna Jamroz-Wiśniewska ◽  
Konrad Rejdak
Keyword(s):  
Peripheral Neuropathy ◽  
Electrophysiological Study ◽  
Middle Aged ◽  
Aged Patients ◽  
Small Fibre Neuropathy ◽  
Aged People ◽  
Small Fibre ◽  
Laboratory Results ◽  
And Gender ◽  
Internal And External Factors

Background and Objectives: Correct assessment and a multidisciplinary approach appear to be extremely important in preventing peripheral neuropathy and its complications. The purpose of this study was to find the correlations and dissimilarities between different types of peripheral neuropathy, the occurrence of pain, and laboratory results. Materials and Methods: This retrospective study assessed 124 patients who were hospitalized in our neurology department due to various types of sensory or motor disturbances. The patients were eventually diagnosed with peripheral neuropathy, based on the electrophysiological study, anamnesis, physical examination, and laboratory results. The whole group was subjected to statistical analysis. Results: The mean age of patients was over 56 years, with a slight woman predominance. A statistically significant (p < 0.05) relationship between the place of residence and gender was seen, where more men than women live in the rural area, while more women than men live in the urban area. Most often we observed symmetric, sensorimotor, demyelinating, inflammatory, and chronic neuropathy. More than 40% of patients reported pain. A statistically significant correlation between the evolution/severity and the occurrence of pain was seen in subacute type (p < 0.05) and small fibre neuropathy (p < 0.01). Conclusions: A higher incidence of peripheral neuropathy in middle-aged people will become essential in the aging society with lifestyle and chronic disorders. Peripheral neuropathy is slightly more common in women than men and its occurrence may be influenced by work performed or internal and external factors. In the study group, more than 40% of patients reported pain, therefore the pain measurement for each patient should be implemented and repeated at every visit. An assessment of sodium level and, in women, markers of neuroinflammation level in the various types of peripheral neuropathy may be an interesting direction for the future.

Semantic Processing of Spoken Words in Alzheimer's Disease: An Electrophysiological Study

1998 ◽  
Vol 10 (3) ◽  
pp. 408-420 ◽  
Author(s):  
Antti Revonsuo ◽  
Raija Portin ◽  
Kirsi Juottonen ◽  
Juha O. Rinne
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Semantic Processing ◽  
Electrophysiological Study ◽  
Semantic Knowledge ◽  
Lexical Selection ◽  
Semantic Representations ◽  
Late Positive Component ◽  
Healthy Elderly ◽  
Spoken Words

Patients suffering from Alzheimer's disease (AD) have severe difficulties in tasks requiring the use of semantic knowledge. The semantic deficits associated with AD have been extensively studied by using behavioral methods. Many of these studies indicate that AD patients have a general deficit in voluntary access to semantic representations but that the structure of the representations themselves might be preserved. However, several studies also provide evidence that to some extent semantic representations in AD may in fact be degraded. Recently, a few studies have utilized event-related brain potentials (ERPs) that are sensitive to semantic factors in order to investigate the electrophysiological correlates of the semantic impairment in AD. Interest has focused on the N400 component, which is known to reºect the on-line semantic processing of linguistic and pictorial stimuli. The results from studies of N400 changes in AD remain somewhat controversial: Some studies report normal or enlarged N400 components in AD, whereas others report diminished ones. One issue not reported in previous studies is whether word-elicited ERPs other than N400 remain normal in AD. In the present study our aim was to find out whether the ERP waveforms N1, P2, N400, and Late Positive Component (LPC) to semantically congruous and incongruous spoken words are abnormal in AD and whether such abnormalities specifically reºect deficiencies in semantic activation in AD. Auditory ERPs from 20 scalp sites to semantically congruous and incongruous final words in spoken sentences were recorded from 17 healthy elderly adults and 9 AD patients. The early ERP waveforms N1 and P2 were relatively normal for the AD patients, but the N400 and LPC effects (amplitude difference between congruous and incongruous conditions) were significantly reduced. We interpret the present results as showing that semantic-conceptual activation and other high-level integration processes are defective in AD. However, a word congruity effect earlier than N400 (phonological mismatch negativity), reflecting lexical selection processes, is at least to some extent preserved in AD.

scholarly journals When dogs meow: an electrophysiological study of lexical-semantic processing in toddlers

2021 ◽  
Author(s):  
Mirella Manfredi ◽  
Moritz M. Daum
Keyword(s):  
Semantic Processing ◽  
Electrophysiological Study ◽  
Age Groups ◽  
Control Group ◽  
Older Children ◽  
N400 Effect ◽  
Brain Potentials ◽  
Lexical Information ◽  
Lexical Semantic ◽  
Two Age Groups

The goal of this study was to investigate lexical–semantic processing at an early phase of language development. Adults often communicate with children using infant-directed speech that typically involves lexical and syntactic modifications such as onomatopoeias (Soderstrom, 2007).Here we asked how and when children start to show an advantage for processing conventional linguistic forms, such as common nouns, and consequently decreasing sensitivity to onomatopoeias. We recorded event-related brain potentials in children of two age groups (16 to 20 months and 24 to 30 months) and in an adult control group during the presentation of the four conditions in which either common nouns or onomatopoeias were presented auditorily followed by either a congruent or incongruent image. The younger children showed a N400 effect only for onomatopoeic words, while the older children showed a N400 effect only for common nouns. The adults show N400 for onomatopoeia and nouns. These different N400 effects suggest that these categories are differently organized in children’s semantic memory and that the acquisition of linguistic abilities affects and modifies semantic processing of different lexical information.

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