scholarly journals A Retrospective Analysis of Pain Etiology in Middle-Aged Patients with Peripheral Neuropathy

Medicina ◽  
2021 ◽  
Vol 57 (8) ◽  
pp. 787
Author(s):  
Anna K. Szewczyk ◽  
Anna Jamroz-Wiśniewska ◽  
Konrad Rejdak
Keyword(s):  
Peripheral Neuropathy ◽  
Electrophysiological Study ◽  
Middle Aged ◽  
Aged Patients ◽  
Small Fibre Neuropathy ◽  
Aged People ◽  
Small Fibre ◽  
Laboratory Results ◽  
And Gender ◽  
Internal And External Factors

Background and Objectives: Correct assessment and a multidisciplinary approach appear to be extremely important in preventing peripheral neuropathy and its complications. The purpose of this study was to find the correlations and dissimilarities between different types of peripheral neuropathy, the occurrence of pain, and laboratory results. Materials and Methods: This retrospective study assessed 124 patients who were hospitalized in our neurology department due to various types of sensory or motor disturbances. The patients were eventually diagnosed with peripheral neuropathy, based on the electrophysiological study, anamnesis, physical examination, and laboratory results. The whole group was subjected to statistical analysis. Results: The mean age of patients was over 56 years, with a slight woman predominance. A statistically significant (p < 0.05) relationship between the place of residence and gender was seen, where more men than women live in the rural area, while more women than men live in the urban area. Most often we observed symmetric, sensorimotor, demyelinating, inflammatory, and chronic neuropathy. More than 40% of patients reported pain. A statistically significant correlation between the evolution/severity and the occurrence of pain was seen in subacute type (p < 0.05) and small fibre neuropathy (p < 0.01). Conclusions: A higher incidence of peripheral neuropathy in middle-aged people will become essential in the aging society with lifestyle and chronic disorders. Peripheral neuropathy is slightly more common in women than men and its occurrence may be influenced by work performed or internal and external factors. In the study group, more than 40% of patients reported pain, therefore the pain measurement for each patient should be implemented and repeated at every visit. An assessment of sodium level and, in women, markers of neuroinflammation level in the various types of peripheral neuropathy may be an interesting direction for the future.

scholarly journals Effects of Routine Checkups and Chronic Conditions on Middle-Aged Patients with Diabetes

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
America E. McGuffee ◽  
Kailyn Chillag ◽  
Amber Johnson ◽  
Regan Richardson ◽  
Hallie Williams ◽  
...  
Keyword(s):  
New York ◽  
Chronic Conditions ◽  
Target Population ◽  
Health Conditions ◽  
Middle Aged ◽  
Aged Patients ◽  
Cross Sectional ◽  
And Gender ◽  
Socioeconomic And Demographic Factors ◽  
The Relationship

Purpose. Middle-aged males and females with diabetes are more likely to have poor physical (PH) and mental health (MH); however, there is limited research determining the relationship between MH and PH and routine check-up in diabetic middle-aged adults, especially by gender. The purpose of this study was to determine whether PH and MH status differ by routine check-up in middle-aged (age 45–64) adults with diabetes in the general population. Methods. This cross-sectional analysis used data from the 2017 BRFSS conducted by the CDC for adults aged 45–64 who reported having diabetes in Florida (N=1183), Kentucky (N=617), Maryland (N=731), New York (N=593), and Ohio (N=754). Multiple logistic regression by state and gender was used to determine the relationship between MH and PH status and routine check-up while controlling for health-related, socioeconomic, and demographic factors. Results. Across states, up to one-half reported good PH (32–50%), over one-half reported good MH (46–67%), and most reported having a routine check-up (87–93%). Adjusted analysis indicated that MH and PH were not significantly related to routine check-up, but both were inversely related to having diabetes plus two other health conditions. Conclusions. Overall, routine check-up was not related to good PH and MH in this target population; however, a number of health conditions were inversely related to good PH and MH status. In a primary care setting for this target population, there may be a low to moderate prevalence of good PH and MH and a high prevalence of having a routine check-up and having multiple health conditions. It is recommended to automatically screen this target population for PH, MH, other chronic conditions, and physical activity and treat concurrently.

scholarly journals Burden of premature atrial beats in middle-aged endurance athletes with and without lone atrial fibrillation versus sedentary controls

2019 ◽  
Vol 27 (14) ◽  
pp. 1555-1563
Author(s):  
Alberto Cipriani ◽  
Riccardo Vio ◽  
Giulio Mastella ◽  
Nicolò Ciarmatori ◽  
Alvise Del Monte ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Paroxysmal Atrial Fibrillation ◽  
Multivariable Analysis ◽  
Endurance Athletes ◽  
Ecg Monitoring ◽  
Middle Aged ◽  
Sports Activity ◽  
Lone Atrial Fibrillation ◽  
Aged Patients ◽  
And Gender

Background The burden of premature atrial beats (PABs) at 24-h electrocardiographic (ECG) monitoring correlates with the risk of atrial fibrillation. It is unknown whether prolonged and intense exercise increases the burden of PABs, thus contributing to the higher prevalence of atrial fibrillation observed in middle-aged athletes. Methods We compared the burden of PABs at 24-h ECG monitoring off therapy in 134 healthy middle-aged (30–60-year-old) competitive athletes who had practised 9 (7-11) h of endurance sports for 8 (4-15) consecutive years, 134 age- and gender-matched healthy sedentary individuals, and 66 middle-aged patients (20 athletes and 46 non-athletes) with ‘lone’ paroxysmal atrial fibrillation. Results More than 50 PABs/24 h or ≥1 run of ≥3 PABs were recorded in 23/134 (17%) healthy athletes and in 29/134 (22%) sedentary controls ( p = 0.61). Healthy athletes with frequent or repetitive PABs were older (median 50 years vs. 43 years, p < 0.01) and had practised sport for a longer time (median 10 years vs. 6 years, p = 0.03). At multivariable analysis only age (odds ratio 1.11, 95% confidence interval 1.04–1.20, p < 0.01) remained an independent predictor of a higher burden of PABs. Also among patients with ‘lone’ paroxysmal atrial fibrillation, there was no difference in the prevalence of >50 PABs/24 h or ≥1 run of ≥3 PABs between athletes (40%) and controls (48%, p = 0.74) . Conclusions Middle-aged endurance athletes, with or without paroxysmal atrial fibrillation, did not show a higher burden of PABs at 24-h ECG monitoring than sedentary controls. Age, but not intensity and duration of sports activity, predicted a higher burden of PABs among healthy athletes.

scholarly journals Influence of genetic and comorbid emotional-affective factors on pre-mild cognitive decline in middle-aged patients

2021 ◽  
Vol 13 (4) ◽  
pp. 66-74
Author(s):  
N. N. Koberskaya ◽  
T. M. Ostroumova ◽  
V. A. Perepelov ◽  
D. S. Smirnov
Keyword(s):  
Cognitive Decline ◽  
Neuropsychological Assessment ◽  
Cortical Atrophy ◽  
Digit Symbol Substitution Test ◽  
Middle Aged ◽  
Aged Patients ◽  
Test Analysis ◽  
Affective Factors ◽  
Aged People ◽  
Cardiovascular Assessment

Recently, maximum attention has been drawn to the earliest forms of cognitive deficit - pre-mild cognitive decline (PMCD), which includes subjective (SjCD) and subtle cognitive decline (SCD), being the most promising in cognitive decline prevention.Objective: to assess the influence of genetic and comorbid emotional-affective factors on PMCD in middle-aged patients.Patients and methods. The study included 50 middle-aged people (60.76±9.5 years) with cognitive complaints. All patients underwent a cardiovascular assessment, including: biochemistry blood test (lipid profile, urea, glucose, vitamin В12, folic acid, homocysteine, thyroid hormones), duplex scan of the extracranial arteries, blood assay for АРОЕ4 determination, neuropsychological assessment with quantitative neuropsychological methods, emotional-affective background evaluation. In addition, magnetic resonance imaging (MRI) with morphometry of the hippocampus was performed in 20 patients.Results and discussion. Arterial hypertension, diabetes mellitus, and changes in laboratory parameters are significantly were more frequent in patients with SCD than patients with SjCD. The neuropsychological assessment showed maximum differences between SjCD and SCD groups in tests that evaluated reaction time (verbal fluency test, trail making test, part A, digit symbol substitution test, and Munsterberg test). Analysis of neuroimaging parameters revealed a smaller volume of the right hippocampus in APOE4 carriers. patients without depression performed significantly better on memory tasks, when depression was included in the analysis. In addition, patients with depression showed a significantly more pronounced degree of cortical atrophy on MRI.Conclusion. Patients with SCD have lower scores in neuropsychological tests than patients with SjCD. In addition, we observed a high significance of cardiovascular and emotional-affective risk factors in the PMCD development, emphasizing the importance of their evaluation and treatment in the management of patients with PMCD.

scholarly journals Clinical-hemodynamic features of ischemic stroke in patients of young age

2020 ◽  
pp. 26-29
Author(s):  
Olena Mialovytska ◽  
Yaroslav Nebor
Keyword(s):  
Ischemic Stroke ◽  
Young People ◽  
Young Patients ◽  
Linear Velocity ◽  
Young Age ◽  
Left Vertebral Artery ◽  
Control Group ◽  
Middle Aged ◽  
Aged Patients ◽  
Aged People

58 patients with ischemic stroke were examined (29 young people — the main group and 29 middle-aged people — control group). Among the examined young patients, cardio embolic subtype of stroke prevailed (66 %), and among middle-aged patients was observed in 10 %. The athe rothrombotic subtype of stroke prevailed in middle-aged people (69 %), and among young people — 24 %. The lacunar subtype of stroke in young people was 3 %, and in middle-aged people — 21 %. Patients of young had such subtypes of strokes as hemodyna mic and hemorheological, which respectively equaled 3 %. In middle age these subtypes of strokes were not observed among the examined patients. In young people the proportion of vascular pools with ische mic stroke was: vertebrobasilar — 41 %, carotid prevailed to some extend — 59 %. In middle-aged people the proportion of strokes prevailed in the carotid pool — 64 %, in the vertebrobasilar it was 29 %. Middle-aged people also had a “combined stroke” (stroke that occurred in several pools at once), it amounted to 7 %. As a result, Doppler study of cerebral vessels proved that in young people linear velocity in the right middle cerebral artery was authentically higher compared with middle-aged patients. At the same time, the linear velocity in middle-aged patients was statistically greater in the left vertebral artery. Keywords: ischemic stroke subtypes, young age, hemodynamic parameters

scholarly journals Assessment of Acute Stress Disorder of Young and Middle-Aged Patients With Acute Myocardial Infarction And Analysis of The Influencing Factors

2021 ◽  
Author(s):  
Minjuan Wu ◽  
Wang Wenqin ◽  
Zhang Xingwei ◽  
Li Junhua
Keyword(s):  
Myocardial Infarction ◽  
Social Support ◽  
Acute Myocardial Infarction ◽  
Cardiac Rehabilitation ◽  
Stress Disorder ◽  
Acute Stress ◽  
Acute Stress Disorder ◽  
Middle Aged ◽  
Aged Patients ◽  
Aged People

Abstract Background: Young and middle-aged people are considered a vulnerable group to experience acute stress disorder (ASD) after acute myocardial infarction (AMI). This study aims to explore influencing factors to ASD in young and middle-aged groups.Methods: 190 patients of 18–60 years of age with acute myocardial infarction were enrolled in this study. We assessed the association between ASD and demographic data, adult attachment, and social support.Results: A total of 190 young and middle-aged people were investigated in this study. Among them, 65 cases were positive for acute stress disorder, with a positive rate of 34.21%. Multivariate stepwise regression showed that attachment-related anxiety, distribution of criminal vessels, perceived support, complications, and attachment-related avoidance are the main factors affecting acute stress disorder of young and middle-aged patients with AMI.Conclusions: The incidence of acute stress disorder in young and middle-aged patients with AMI is high. We should strengthen social support and pay attention to the psychological state of patients in the process of follow-up cardiac rehabilitation to improve their ability to deal with acute stress events and actively participate in postoperative cardiac rehabilitation.

scholarly journals Prevalence Of Partial Edentulism, Complete Edentulism And Single Complete Opposing Partial Edentulism In Relation To The Age Groups And Gender In The Local Population Of Hyderabad

2017 ◽  
Vol 08 (01) ◽  
pp. 26-30
Author(s):  
Farzana Memon ◽  
Diya Ram Khatri ◽  
Daud Mirza ◽  
Salwa Memon
Keyword(s):  
Old Age ◽  
Statistical Significance ◽  
Local Population ◽  
Age Groups ◽  
Complete Denture ◽  
Middle Aged ◽  
Aged Patients ◽  
And Gender ◽  
Male Subjects ◽  
Edentulous Jaws

Objective: This study was carried out to evaluate the prevalence of partial edentulism, complete edentulism and complete edentulous arch opposing the partial edentulous arches in relation to the various age groups and gender in local population of Hyderabad. Materials and Methods: A cross-sectional study was conducted at the Department of Prosthodontic, Isra Dental College, Hyderabad. Duration of the study was 6 months, from January 2016 to June, 2016. A total 504 patients were selected for this study on the basis of history and clinical examination. The selected subjects were divided into six age groups. Data was statistically analysed by SPSS statistics software version 21. Descriptive statistics such as frequencies, percentages, mean and cross tabulation were applied to test the variables. The level of statistical significance was set to 0.5%. Results: The results showed that out of 504 selected subjects 426 (84.5%) subjects were partially edentulous, as compared to completely edentulous patients who numbered only 66 (13.1%) whereas 7 (1.4%) subjects had complete edentulous upper ridge and partially edentulous lower ridge, only 5 (1%) subjects had complete edentulous lower ridge and partially edentulous upper ridge. Partially edentulous jaws were more prevalent in females and in middle aged patients ranging from 31-40 years and completely edentulous jaws were more prevalent among male subjects in old age subjects who were above 60 years of age. Single complete denture opposing partially edentulous ridges were more common in females and in patients who were above 30 years of age. Conclusion: This study concluded that the partially edentulous jaws were more prevalent as compared to completely edentulous jaws. Partially edentulous jaws were more prevalent in females and in middle aged patients while completely edentulous jaws were more prevalent among male subjects and in old age subjects of either age, whereas single complete denture opposing partially edentulous ridges were more common in females and in patients who were above 30 years of age

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