scholarly journals Lipocalin-2 deficiency prevents endothelial dysfunction associated with dietary obesity: role of cytochrome P450 2C inhibition

2011 ◽  
Vol 165 (2) ◽  
pp. 520-531 ◽  
Author(s):  
Jacky TC Liu ◽  
Erfei Song ◽  
Aimin Xu ◽  
Thorsten Berger ◽  
Tak W Mak ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Endothelial Dysfunction ◽  
Lipocalin 2 ◽  
Cytochrome P450 2C ◽  
Dietary Obesity

Cytochrome p450 2C (CYP2C) in ischemic heart injury and vascular dysfunctionThis paper is one of a selection of papers published in this Special Issue, entitled Young Investigator's Forum.

2006 ◽  
Vol 84 (1) ◽  
pp. 15-20 ◽  
Author(s):  
Manreet K. Chehal ◽  
David J. Granville
Keyword(s):  
Cytochrome P450 ◽  
Ischemic Heart ◽  
Epoxyeicosatrienoic Acids ◽  
Special Issue ◽  
Ischemia And Reperfusion Injury ◽  
Current Review ◽  
Cytochrome P450 2C ◽  
Heart Injury ◽  
Selection Of

The cytochrome p450 2C (CYP2C) monooxygenase family is a key player in the generation of epoxyeicosatrienoic acids. It has recently become apparent that CYP plays an important role in cardiovascular physiology and contributes to the pathogenesis of various cardiovascular diseases. In particular, several studies have demonstrated a role for these enzymes in cardiac ischemia and reperfusion injury. The current review summarizes the role of the CYP epoxygenase, CYP2C9, in ischemic heart disease and vascular homeostasis.

Role of Cytochrome P450 2C Epoxygenases in Hypoxia-Induced Cell Migration and Angiogenesis in Retinal Endothelial Cells

2008 ◽  
Vol 49 (3) ◽  
pp. 1242 ◽  
Author(s):  
U. Ruth Michaelis ◽  
Ning Xia ◽  
Eduardo Barbosa-Sicard ◽  
John R. Falck ◽  
Ingrid Fleming
Keyword(s):  
Endothelial Cells ◽  
Cytochrome P450 ◽  
Cell Migration ◽  
Retinal Endothelial Cells ◽  
Cytochrome P450 2C

Pharmacogenetics of Clozapine: In Vivo Role of Cytochrome P450 Isoforms and P-Glycoprotein

2008 ◽  
Vol 41 (05) ◽  
Author(s):  
E Jaquenoud-Sirot ◽  
B Knezevic ◽  
G Perla Morena ◽  
P Baumann ◽  
CB Eap
Keyword(s):  
Cytochrome P450 ◽  
P Glycoprotein ◽  
Cytochrome P450 Isoforms

The critical biomechanical role of Lipocalin 2 in the crosstalk between endothelium and osteoblasts in unloading conditions.

2016 ◽  
Author(s):  
Vimal Veeriah ◽  
Mattia Capulli ◽  
Angelo Zanniti ◽  
Suvro Chatterjee ◽  
Nadia Rucci ◽  
...  
Keyword(s):  
Lipocalin 2
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