The Effects of Exposure to "Synthetic" Chemicals on Human Health: A Review

Risk Analysis ◽  
1995 ◽  
Vol 16 (3) ◽  
pp. 367-376
Author(s):  
Peter M. VanDoren
Keyword(s):  
Human Health ◽  
Synthetic Chemicals

scholarly journals Identifying and designing chemicals with minimal acute aquatic toxicity

2014 ◽  
Vol 112 (20) ◽  
pp. 6289-6294 ◽  
Author(s):  
Jakub Kostal ◽  
Adelina Voutchkova-Kostal ◽  
Paul T. Anastas ◽  
Julie Beth Zimmerman
Keyword(s):  
Human Health ◽  
Industrial Ecology ◽  
Aquatic Toxicity ◽  
Rapid Assessment ◽  
Chemical Properties ◽  
Design Guidelines ◽  
Synthetic Chemicals ◽  
Acute Aquatic Toxicity ◽  
Stocks And Flows ◽  
Inherent Nature

Industrial ecology has revolutionized our understanding of material stocks and flows in our economy and society. For this important discipline to have even deeper impact, we must understand the inherent nature of these materials in terms of human health and the environment. This paper focuses on methods to design synthetic chemicals to reduce their intrinsic ability to cause adverse consequence to the biosphere. Advances in the fields of computational chemistry and molecular toxicology in recent decades allow the development of predictive models that inform the design of molecules with reduced potential to be toxic to humans or the environment. The approach presented herein builds on the important work in quantitative structure–activity relationships by linking toxicological and chemical mechanistic insights to the identification of critical physical–chemical properties needed to be modified. This in silico approach yields design guidelines using boundary values for physiochemical properties. Acute aquatic toxicity serves as a model endpoint in this study. Defining value ranges for properties related to bioavailability and reactivity eliminates 99% of the chemicals in the highest concern for acute aquatic toxicity category. This approach and its future implementations are expected to yield very powerful tools for life cycle assessment practitioners and molecular designers that allow rapid assessment of multiple environmental and human health endpoints and inform modifications to minimize hazard.

Developing a screening method for the evaluation of environmental and human health risks of synthetic chemicals in the mining industry

2011 ◽  
Vol 101 (1-4) ◽  
pp. 1-20 ◽  
Author(s):  
Khareen Singh ◽  
Christian Ihlenfeld ◽  
Christopher Oates ◽  
Jane Plant ◽  
Nikolaos Voulvoulis
Keyword(s):  
Human Health ◽  
Health Risks ◽  
Screening Method ◽  
Mining Industry ◽  
Human Health Risks ◽  
Synthetic Chemicals

scholarly journals Potensi Rumput Laut Dalam Menghambat Pertumbuhan Jamur Aspergillus flavus

2019 ◽  
Vol 9 (1) ◽  
pp. 82
Author(s):  
KETUT SRIE MARHAENI JULYASIH ◽  
ARIKA PURNAWATI
Keyword(s):  
Adverse Effects ◽  
Natural Resources ◽  
Human Health ◽  
Aspergillus Flavus ◽  
Fungal Growth ◽  
Gracilaria Verrucosa ◽  
Natural Control ◽  
Fungal Contamination ◽  
Food Items ◽  
Synthetic Chemicals

Potential of Seaweed in the Inhibition of Fungi Growth Aspergillus flavus. This use of synthetic chemicals as a controller of fungal growth in foodstuffs can have adverse effects on health, so it needs natural control ingredients that do not have an impact on human health. Various types of fungi such as Aspergillus flavus attack a lot of food items after harvest, these fungi can produce aflatoxin which is very toxic to consumers. Aflatoxin cannot be neutralized through cooking so efforts to avoid fungal contamination need to be done. One of the natural fungi controllers is by utilizing natural resources, including seaweed.  Development of seaweed as an antifungal is an alternative that needs to be realized.  For this reason, it is necessary to examine the potential inhibitory of seaweed A. flavus development. This study examined six types of seaweed like Gracilaria verrucosa, Euchema spinosum, Ulva lactuca, Ulva reticulata, Euchema edule, and Padina sp.  The results showed that Padina sp. seaweed has a very strong potential  inhibitory compared to other types of seaweed.

Lycopene alleviates sulfamethoxazole-induced hepatotoxicity in grass carp (Ctenopharyngodon idellus) via suppression of oxidative stress, inflammation and apoptosis

2020 ◽  
Vol 11 (10) ◽  
pp. 8547-8559
Author(s):  
Hongjing Zhao ◽  
Yu Wang ◽  
Mengyao Mu ◽  
Menghao Guo ◽  
Hongxian Yu ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Secondary Metabolites ◽  
Human Health ◽  
Grass Carp ◽  
Aquatic Environment ◽  
Ctenopharyngodon Idellus

Antibiotics are used worldwide to treat diseases in humans and other animals; most of them and their secondary metabolites are discharged into the aquatic environment, posing a serious threat to human health.

Emerging Nutrition Gaps in a World of Affluence - Micronutrient Intake and Status Globally

2011 ◽  
Vol 81 (4) ◽  
pp. 238-239 ◽  
Author(s):  
Manfred Eggersdorfer ◽  
Paul Walter
Keyword(s):  
Developing Countries ◽  
Human Health ◽  
Old Age ◽  
Molecular Basis ◽  
Health Benefit ◽  
Developed Countries ◽  
Micronutrient Deficiencies ◽  
New Science ◽  
Health And Nutrition ◽  
Micronutrient Intake

Nutrition is important for human health in all stages of life - from conception to old age. Today we know much more about the molecular basis of nutrition. Most importantly, we have learnt that micronutrients, among other factors, interact with genes, and new science is increasingly providing more tools to clarify this interrelation between health and nutrition. Sufficient intake of vitamins is essential to achieve maximum health benefit. It is well established that in developing countries, millions of people still suffer from micronutrient deficiencies. However, it is far less recognized that we face micronutrient insufficiencies also in developed countries.

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