Psychometric properties of a Norwegian version of Multiple Sclerosis Impact Scale (MSIS-29)

Background Investigations using classical test theory support the psychometric properties of the original version of the Multiple Sclerosis Impact Scale (MSIS-29v1), a disease-specific measure of multiple sclerosis (MS) impact (physical and psychological subscales). Later, assessments of the MSIS-29v1 in an MS community-based sample using Rasch analysis led to revisions of the instrument’s response options (MSIS-29v2). Objective The objective of this paper is to evaluate the psychometric properties of the MSIS-29v1 in a clinical trial cohort of relapsing–remitting MS patients (RRMS). Methods Data from 600 patients with RRMS enrolled in the SELECT clinical trial were used. Assessments were performed at baseline and at Weeks 12, 24, and 52. In addition to traditional psychometric analyses, Item Response Theory (IRT) and Rasch analysis were used to evaluate the measurement properties of the MSIS-29v1. Results Both MSIS-29v1 subscales demonstrated strong reliability, construct validity, and responsiveness. The IRT and Rasch analysis showed overall support for response category threshold ordering, person-item fit, and item fit for both subscales. Conclusions Both MSIS-29v1 subscales demonstrated robust measurement properties using classical, IRT, and Rasch techniques. Unlike previous research using a community-based sample, the MSIS-29v1 was found to be psychometrically sound to assess physical and psychological impairments in a clinical trial sample of patients with RRMS.

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Tried and tested: the psychometric properties of the multiple sclerosis impact scale (MSIS-29) in a population-based study

Multiple Sclerosis Journal ◽

10.1177/1352458508096872 ◽

2009 ◽

Vol 15 (1) ◽

pp. 75-80 ◽

Cited By ~ 36

Author(s):

OM Gray ◽

GV McDonnell ◽

SA Hawkins

Keyword(s):

Multiple Sclerosis ◽

Psychometric Properties ◽

Convergent Validity ◽

Population Based ◽

Population Based Study ◽

North East ◽

The North ◽

Impact Scale ◽

Disability Status ◽

Physical Impact

Objective To investigate the psychometric properties of the Multiple Sclerosis Impact Scale (MSIS-29) and to assess the relationship between the Kurtzke Expanded Disability Status Scale and the physical and psychological parts of this score. Methods A population-based study identified cases with definite multiple sclerosis (MS) in the north-east region of Ireland. They were examined and completed the MSIS-29. Cases were classified as mild (Expanded Disability Status Score (EDSS) 0–3.0), moderate (EDSS 3.5–5.5), or severe (6.0–9.5) MS. Results The 248 participants (82 male, 166 female) had a mean age of 49.1 years (SD 12.4). EDSS ranged from 0 to 9.5 (median 6.0). Data quality was excellent (0.02% missing data), physical and psychological scores spanned the entire range with low floor and ceiling effects. Internal consistency was high (Cronbach’s alpha 0.97 – physical score, 0.93 – psychological score). The convergent validity of the physical impact score of the MSIS-29 with the Kurtzke EDSS was confirmed with a high Spearman’s rank coefficient correlation of 0.63 ( P = 0.01). Physical impact scores for mild, moderate, and severe disability as were statistically different at 25.9%, 48.0%, and 63.9%, respectively. Mean psychological score was non-significantly higher in the moderately disabled group at 47.4% compared with the severely disabled at 44.3% ( P = 0.58). Conclusions The MSIS-29 is an acceptable, reliable, and valid method of recording quality of life. A significant relationship between higher physical impact scores of the MSIS-29 and higher Kurtzke EDSS values suggests that is may be of use in clinical trials to monitor progression.

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An investigation into the Relationship between the Multiple Sclerosis Impact Scale (MSIS-29) and Predicted Medication Adherence as measured by the Morisky Medication Adherence Scale (MMAS-8)

10.26226/morressier.59a3e8b6d462b8028d8955db ◽

2017 ◽

Author(s):

Mark Gudesblatt

Keyword(s):

Multiple Sclerosis ◽

Medication Adherence ◽

Impact Scale ◽

Morisky Medication Adherence Scale ◽

Adherence Scale ◽

The Relationship

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Nutritional status of multiple sclerosis (MS) patients attending Kasr Alainy MS unit: an exploratory cross-sectional study

Journal of Egyptian Public Health Association ◽

10.1186/s42506-021-00080-3 ◽

2021 ◽

Vol 96 (1) ◽

Author(s):

Zeinab E. Afifi ◽

Rania I. Shehata ◽

Asmaa F. El Sayed ◽

El Sayed M. Hammad ◽

Marwa R. Salem

Keyword(s):

Multiple Sclerosis ◽

Nutritional Status ◽

Dietary Habits ◽

Care Service ◽

Structured Interview ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Level Measurement ◽

Impact Scale

Abstract Background Nutrition was claimed to be a factor in MS causation, course, complications, and management. Several studies were conducted to assess the nutritional status of MS patients; however, few studies were conducted to assess this problem in Egypt. Therefore, the purpose of the current study was to assess the nutritional status of a sample of MS patients. Methods The researchers conducted an exploratory cross-sectional study among 76 relapsing-remitting MS (RRMS) patients attending Kasr Alainy Multiple Sclerosis Unit (KAMSU) from October 2018 to January 2019 to assess the nutritional status of a sample of MS patients. Data were collected using a structured interview questionnaire including an inquiry about the socioeconomic status, and nutritional status using anthropometric measurements, patient-generated subjective global assessment (PG-SGA), semi-quantitative food frequency questionnaires (SQFFQ), and hemoglobin level measurement. Assessment of fatigue was done using the Modified Fatigue Impact Scale 5-items version. Results The mean age of the study participants was 30 ± 6 years. The disease duration ranged from 2 to 264 months. Malnutrition was prevalent among 67.1% (27.6 % overweight, 36.8% obese, and 2.6% underweight). Half of the investigated patients were anemic. According to the PG-SGA, more than half of the studied patients (53.9%) were classified as moderately or suspected malnourished. The unhealthy dietary habits such as taking only a few meals, junk food intake and skipping breakfast were observed in considerable proportions of the group. The SQFFQ revealed overconsumption of energy and fat, and less than acceptable consumption of dietary fibers by most of the studied patients. Conclusions Overweight, obesity, anemia, and unhealthy dietary habits were prevalent among the RRMS patients attending the KAMSU. Nutrition care service is extremely needed for this group of patients.

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Psychometric properties of the Norwegian version of the clinical learning environment comparison survey

Nursing Open ◽

10.1002/nop2.742 ◽

2020 ◽

Author(s):

Camilla Olaussen ◽

Lars‐Petter Jelsness‐Jørgensen ◽

Christine Raaen Tvedt ◽

Dag Hofoss ◽

Ingunn Aase ◽

...

Keyword(s):

Learning Environment ◽

Psychometric Properties ◽

Clinical Learning ◽

Clinical Learning Environment ◽

Norwegian Version

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Psychometric properties of the short form of the Stroke Impact Scale in German-speaking stroke survivors

Health and Quality of Life Outcomes ◽

10.1186/s12955-021-01826-5 ◽

2021 ◽

Vol 19 (1) ◽

Author(s):

Anna Coppers ◽

Jens Carsten Möller ◽

Detlef Marks

Keyword(s):

Factor Analysis ◽

Psychometric Properties ◽

Short Form ◽

Trial Registration ◽

Cognitive Domain ◽

Retest Reliability ◽

Stroke Impact Scale ◽

Impact Scale ◽

German Speaking ◽

Test Retest Reliability

Abstract Background The short form of the Stroke Impact Scale (SF-SIS) consists of eight questions and provides an overall index of health-related quality of life after stroke. The goal of the study was the evaluation of construct validity, reliability and responsiveness of the SF-SIS for the use in German-speaking stroke patients in rehabilitation. Methods The SF-SIS, the Stroke Impact Scale 2.0 (SIS 2.0), EQ-5D-5L, National Institutes of Health Stroke Scale (NIHSS) and de Morton Mobility Index were assessed in 150 inpatients after stroke, with a second measurement two weeks later for the analyses of responsiveness. In 55 participants, the test–retest-reliability was assessed one week after the first measurement. The study was designed following the recommendations of the COSMIN initiative. Results The correlations of the SF-SIS with the SIS 2.0 (ρ = 0.90), as well as the EQ-5D-5L (ρ = 0.79) were high, as expected. There was adequate discriminatory ability of the SF-SIS index between patients who were less and more severely affected by stroke, as assessed by the NIHSS. Exploratory factor analysis indicated a two-factor structure of the SF-SIS explaining 59.9% of the total variance, providing better model fit in the confirmatory factor analysis than the one-factorial structure. Analyses of test–retest-reliability showed an intraclass correlation coefficient of 0.88 (95% CI 0.75–0.94). Hypotheses concerning responsiveness were not confirmed due to lower correlations between the assessments change scores. Conclusion Results of this analysis of the SF-SIS’s psychometric properties are matching with the validity analysis of the English original version, confirming the high correlations with the Stroke Impact Scale and the EQ-5D-5L. Examination of structural validity did not confirm the presumed unidimensionality of the scale and found evidence of an underlying two-factor solution with a physical and cognitive domain. Sufficient test–retest reliability and internal consistency were found. In addition, this study provides first results for the responsiveness of the German version. Trial registration The study was registered at the German Clinical Trials Register. Trial registration number: DRKS00011933, date of registration: 07.04.2017

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