scholarly journals Understanding heterogeneity in meta-analysis: the role of meta-regression

2009 ◽  
Vol 63 (10) ◽  
pp. 1426-1434 ◽  
Author(s):  
W. L. Baker ◽  
C. Michael White ◽  
J. C. Cappelleri ◽  
J. Kluger ◽  
C. I. Coleman ◽  
...  
2020 ◽  
Author(s):  
Hossein Dabiriyan Tehrani ◽  
Sara Yamini

This systematic review aimed to find attitudes toward Altruistic and Game-playing love styles across individualistic and collectivistic cultures. Addressing major moderators concerning Altruistic and Game-playing love styles are the secondary objectives of this review. This review included 102 articles comprising samples from 37 countries (N = 41997). The findings of this meta-analysis show that there is a collectivistic and individualistic difference in Game-playing but not in the Altruistic love style. Collectivistic and individualistic cultures, on average, demonstrate the same perception concerning the Altruistic love style, whereas collectivistic culture shows the Game-playing love style more strongly. To explain the role of moderators in key measures, the subgroup analysis and meta-regression show that both Game-playing and Altruistic love styles decline by increasing the length of the relationship. Likewise, having children affects these love styles such that the Altruistic love style is improved, and the Game-playing love style is reduced by the presence of children in families.


2018 ◽  
Vol 56 (8) ◽  
pp. 841-852 ◽  
Author(s):  
Bernardo Antonio Agostini ◽  
Kaue Farias Collares ◽  
Francine dos Santos Costa ◽  
Marcos Britto Correa ◽  
Flavio Fernando Demarco

2021 ◽  
Vol 10 ◽  
pp. 114-129
Author(s):  
Udayan Karnatak ◽  
Chirag Malik

The effect of analyst presence on underpricing has shown a contrasting result. By synthesizing the result using meta-analysis for twelve studies with more than 20400 firms we found conclusive evidence of the relation between analyst presence and underpricing of IPOs. With the increase in analyst presence by 1% the IPO underpricing increases by 4.9%. Moreover, meta-regression between effect size and moderator variables found the significant and positive role of the reputed underwriter to increase underpricing when the IPO has coverage of analysts. Our results are striking for the US market IPOs in which reputed underwriters as moderator affect underpricing significantly and positively which shows reputation increase information asymmetry. Whereas in emerging markets IPOs reputed underwriters increase market efficiency and information symmetry.


2019 ◽  
Author(s):  
Elizabeth Tipton ◽  
James E Pustejovsky ◽  
Hedyeh Ahmadi

At the beginning of the development of meta-analysis, understanding the role of moderators was given the highest priority, with meta-regression provided as a method for achieving this goal. Yet in current practice, meta-regression is not as commonly used as anticipated. This paper seeks to understand this mismatch by reviewing the history of meta-regression methods over the past 40 years. We divide this time span into four periods and examine three types of methodological developments within each period: technical, conceptual, and practical. Our focus is broad and includes development of methods in the fields of education, psychology, and medicine. We conclude the paper with a discussion of five consensus points, as well as open questions and areas of research for the future.


2021 ◽  
Author(s):  
Filippo Gambarota ◽  
Naotsugu Tsuchiya ◽  
Massimiliano Pastore ◽  
Nicola Di Polito ◽  
Paola Sessa

The relationship between consciousness and working memory (WM) has been recently debated both at the theoretical and methodological levels (Persuh et al., 2018; Velichkovsky, 2017). While there is behavioral and neural evidence that argues for the existence of unconscious WM, several methodological concerns have been raised, rendering this issue highly controversial. To address the robustness of the previous findings, here we adopt a meta-analytic approach to estimate the effect size and heterogeneity of the previously reported unconscious WM results, also including unpublished results. We used meta-regression to isolate relevant experimental variables, in particular, consciousness manipulation and WM paradigm to identify the source of the heterogeneity in the reported effect size of the unconscious WM. Our meta-analysis supports the existence of the unconscious WM effect and critically reveals several experimental variables that contribute to relevant heterogeneity. Our analysis clarifies several theoretical and methodological issues. We recommend that future studies explicitly operationalize the definition of consciousness, standardize the methodology and systematically explore the role of critical variables for the unconscious WM effect.


2019 ◽  
Vol 20 (6) ◽  
pp. 842-858 ◽  
Author(s):  
Mahnaz Bahri Khomami ◽  
Anju E. Joham ◽  
Jacqueline A. Boyle ◽  
Terhi Piltonen ◽  
Chavy Arora ◽  
...  

2020 ◽  
Vol 19 (1) ◽  
Author(s):  
Walter Masson ◽  
Martin Lobo ◽  
Daniel Siniawski ◽  
Graciela Molinero ◽  
Gerardo Masson ◽  
...  

BMC Cancer ◽  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Haiyan Xu ◽  
Zhenhua Liu ◽  
Hongtai Shi ◽  
Chunbin Wang

Abstract Background A higher vitamin D intake improves the prognosis of early stage breast cancer (BC) patients. We hypothesized that vitamin D intake should refer to vitamin D receptor (VDR) expression. In order to prove this hypothesis, we first intend to evaluate the correlation between VDR expression and prognosis of BC patients using meta-analysis. Methods Literatures from PubMed, Embase, and the Cochrane Library (last update by May 20, 2020) were retrieved to find studies assessing the prognostic role of VDR in BC. The hazard ratios (HRs) for patients’ survival were extracted for pooled analyses. Subgroup analysis, sensitivity analysis and meta-regression were performed to explore the sources of heterogeneity. Results Seven articles containing eight studies with 2503 patients were enrolled. The results from the pooled analyses showed that the VDR expression generally had no relationship with BC patients’ overall survival (OS), disease-free survival (DFS), cancer-specific survival (CSS), and progression-free survival (PFS) (P > 0.05). Because only the number of studies exploring the relationship between VDR expression and OS is greater than five and there is heterogeneity, we explored the sources of heterogeneity of these studies. Subgroup analyses showed that the VDR expression in the nucleus had no relationship with OS, but high total VDR expression in the nucleus and cytoplasm was related to a better OS (pooled HR = 0.41; 95% CI = 0.18–0.95; P = 0.038). In addition, in subgroup of studies using cut-off values other than ‘immunoreactive score (IRS)>5’ and ‘IRS > 25′, high VDR expression was associated with a better OS (pooled HR = 0.47; 95% CI = 0.30–0.74; P = 0.001). Sensitivity analysis showed that the result pattern was not obviously affected by any single study. Meta-regression showed that the source of heterogeneity was not country (P = 0.657), pathological type (P = 0.614), molecular type (P = 0.423), staining location (P = 0.481), or cut-off value (P = 0.509). Conclusions The protein expression level of VDR in entire BC cells evaluated by immunohistochemistry is related to the OS of BC patients. It is expected that a more individualized vitamin D intake and a more accurate prognosis assessment can be recommended for BC patients based on the VDR expression. Of course, more preclinical and clinical studies are needed.


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