Role of insulin sensitivity and beta cell function in the development of periodontal disease in adults without diabetes

2013 ◽  
Vol 40 (12) ◽  
pp. 1079-1086 ◽  
Author(s):  
Petra Timonen ◽  
Tuomas Saxlin ◽  
Matti Knuuttila ◽  
Anna Liisa Suominen ◽  
Antti Jula ◽  
...  
Keyword(s):  
Insulin Sensitivity ◽  
Periodontal Disease ◽  
Beta Cell ◽  
Beta Cell Function ◽  
Cell Function

Effect of troglitazone on insulin sensitivity and pancreatic beta-cell function in women at high risk for NIDDM

Diabetes ◽  
1996 ◽  
Vol 45 (11) ◽  
pp. 1572-1579 ◽  
Author(s):  
K. Berkowitz ◽  
R. Peters ◽  
S. L. Kjos ◽  
J. Goico ◽  
A. Marroquin ◽  
...  
Keyword(s):  
Insulin Sensitivity ◽  
High Risk ◽  
Beta Cell ◽  
Beta Cell Function ◽  
Cell Function ◽  
Pancreatic Beta Cell ◽  
Pancreatic Beta Cell Function

Indices of insulin sensitivity, beta cell function and serum proinsulin levels in the polycystic ovary syndrome

2006 ◽  
Vol 127 (1) ◽  
pp. 99-105 ◽  
Author(s):  
Dimitrios Panidis ◽  
Djuro Macut ◽  
Dimitrios Farmakiotis ◽  
David Rousso ◽  
Anargyros Kourtis ◽  
...  
Keyword(s):  
Insulin Sensitivity ◽  
Polycystic Ovary Syndrome ◽  
Beta Cell ◽  
Beta Cell Function ◽  
Cell Function ◽  
Polycystic Ovary ◽  
Ovary Syndrome

scholarly journals A Triple Threat? The Role of Diet, Nutrition, and the Microbiota in T1D Pathogenesis

2021 ◽  
Vol 8 ◽  
Author(s):  
Emma E. Hamilton-Williams ◽  
Graciela L. Lorca ◽  
Jill M. Norris ◽  
Jessica L. Dunne
Keyword(s):  
Beta Cell ◽  
Intestinal Microbiota ◽  
Beta Cell Function ◽  
Cell Function ◽  
The Body ◽  
Islet Autoimmunity ◽  
Potential Mechanism ◽  
Modifiable Factors ◽  
And Function

In recent years the role of the intestinal microbiota in health and disease has come to the forefront of medical research. Alterations in the intestinal microbiota and several of its features have been linked to numerous diseases, including type 1 diabetes (T1D). To date, studies in animal models of T1D, as well as studies in human subjects, have linked several intestinal microbiota alterations with T1D pathogenesis. Features that are most often linked with T1D pathogenesis include decreased microbial diversity, the relative abundance of specific strains of individual microbes, and altered metabolite production. Alterations in these features as well as others have provided insight into T1D pathogenesis and shed light on the potential mechanism by which the microbiota plays a role in T1D pathogenesis, yet the underlying factors leading to these alterations remains unknown. One potential mechanism for alteration of the microbiota is through diet and nutrition. Previous studies have shown associations of diet with islet autoimmunity, but a direct contributing factor has yet to be identified. Diet, through introduction of antigens and alteration of the composition and function of the microbiota, may elicit the immune system to produce autoreactive responses that result in the destruction of the beta cells. Here, we review the evidence associating diet induced changes in the intestinal microbiota and their contribution to T1D pathogenesis. We further provide a roadmap for determining the effect of diet and other modifiable factors on the entire microbiota ecosystem, including its impact on both immune and beta cell function, as it relates to T1D. A greater understanding of the complex interactions between the intestinal microbiota and several interacting systems in the body (immune, intestinal integrity and function, metabolism, beta cell function, etc.) may provide scientifically rational approaches to prevent development of T1D and other childhood immune and allergic diseases and biomarkers to evaluate the efficacy of interventions.

scholarly journals OR31-6 Insulin Sensitivity and Pancreatic Beta-Cell Function in Patients with Primary Aldosteronism

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Shivraj Grewal ◽  
Andin Fosam ◽  
Liam Chalk ◽  
Arjun Deven ◽  
Mari Suzuki ◽  
...  
Keyword(s):  
Insulin Sensitivity ◽  
Beta Cell ◽  
Primary Aldosteronism ◽  
Beta Cell Function ◽  
Cell Function ◽  
Pancreatic Beta Cell ◽  
Pancreatic Beta Cell Function

Role of the Interaction Between Nck1 and PERK in Pancreatic Beta Cell Function and Survival

2021 ◽  
Vol 45 (7) ◽  
pp. S34
Author(s):  
Laure Monteillet ◽  
Émilie Courty ◽  
Nathalie Jouvet ◽  
Marco Gasparrini ◽  
Cindy Baldwin ◽  
...  
Keyword(s):  
Beta Cell ◽  
Beta Cell Function ◽  
Cell Function ◽  
Pancreatic Beta Cell ◽  
Pancreatic Beta Cell Function

Glycemic Efficacy of Canagliflozin (CANA) is Largely Independent of Baseline Beta-Cell Function or Insulin Sensitivity

2014 ◽  
Vol 38 (5) ◽  
pp. S54
Author(s):  
Bernard Zinman ◽  
David Matthews ◽  
Cindy Tong ◽  
Gary Meininger ◽  
David Polidori
Keyword(s):  
Insulin Sensitivity ◽  
Beta Cell ◽  
Beta Cell Function ◽  
Cell Function
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