Psoriasis comorbidity affects multiple sclerosis neurological progression: a retrospective case - control analysis

2017 ◽  
Vol 31 (12) ◽  
pp. 2055-2061 ◽  
Author(s):  
G. Miron ◽  
M. Gurevich ◽  
S. Baum ◽  
A. Achiron ◽  
A. Barzilai
2009 ◽  
Vol 2009 ◽  
pp. 1-5 ◽  
Author(s):  
Florence Trivin ◽  
Eveline Boucher ◽  
Elodie Vauléon ◽  
Isabelle Cumin ◽  
Elisabeth Le Prisé ◽  
...  

Objectives. Esophageal carcinoma and cirrhosis have the overlapping etiologic factors.Methods. In a retrospective analysis conducted in 2 Breton institutions we wanted to asses the frequency of this association and the outcome of these patients in a case-control study where each case (cirrhosis and esophageal cancer) was paired with two controls (esophageal cancer).Results. In a 10-year period, we have treated 958 esophageal cancer patients; 26 (2.7%) had a cirrhosis. The same treatments were proposed to the 2 groups; cases received nonsignificantly different radiation and chemotherapy dose than controls. Severe toxicities and deaths were more frequent among the cases. At the end of the treatment 58% of the cases and 67% of the controls were in complete remission; median and 2-year survival were not different between the 2 groups. All 4 Child-Pugh B class patients experienced severe side effects and 2 died during the treatment.Conclusions. This association is surprisingly infrequent in our population! Child-Pugh B patients had a dismal prognosis and a bad tolerance to radiochemotherapy; Child-Pugh A patients have the same tolerance and the same prognosis as controls and the evidence of a well-compensated cirrhosis has not modified our medical options.


Author(s):  
Dr. Laurel Henderson ◽  
Mrs. Amna Imran ◽  
Ms. Pardis Barati Mahvar ◽  
Mr. Andrew Sanapanya ◽  
Dr. Parish P. Sedghizadeh

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