Inhibition of LPS induced neurochemical imbalance and oxidative stress by pigmented and non-pigmented rice bran extracts

2018 ◽  
Vol 43 (3) ◽  
pp. e12735 ◽  
Author(s):  
Saroj Yadav ◽  
Jayadeep Padmanbhan Appukuttan
Keyword(s):  
Oxidative Stress ◽  
Rice Bran ◽  
Pigmented Rice ◽  
And Oxidative Stress

Atherosclerosis-related inflammation and oxidative stress are improved by rice bran enzymatic extract

2016 ◽  
Vol 26 ◽  
pp. 610-621 ◽  
Author(s):  
Cristina Perez-Ternero ◽  
Beatriz Bermudez Pulgarin ◽  
Maria Alvarez de Sotomayor ◽  
Maria Dolores Herrera
Keyword(s):  
Oxidative Stress ◽  
Rice Bran ◽  
Enzymatic Extract ◽  
And Oxidative Stress

scholarly journals Changes in Bone Metabolism and Antioxidant Defense Systems in Menopause-Induced Rats fed Bran Extract from Dark Purple Rice (Oryza sativa L. Cv. Superjami)

Nutrients ◽  
2021 ◽  
Vol 13 (9) ◽  
pp. 2926
Author(s):  
Soo Im Chung ◽  
Su Noh Ryu ◽  
Mi Young Kang
Keyword(s):  
Oxidative Stress ◽  
Lipid Peroxidation ◽  
Bone Loss ◽  
Bone Metabolism ◽  
Rice Bran ◽  
Antioxidant Defense ◽  
Control Group ◽  
Defense Systems ◽  
Antioxidant Defense Systems ◽  
And Oxidative Stress

Menopause is a matter of concern for women’s health due to a deficiency of female hormones; additionally, reactive oxygen species and aging can cause osteoporosis. Food becomes increasingly interesting as a menopausal woman’s alternative to hormone therapy. The effects of ethanol extracts from dark purple Superjami rice bran on bone metabolism and antioxidant defense systems in menopause-induced animal models were evaluated. Female rats underwent sham surgery or were ovariectomized to induce a menopause-like state. Rats were divided into a sham control group (SHAM), an ovariectomized control group (OVX), and an ovariectomized grou supplemented with Superjami rice bran extract group (OVX-S) and fed for 8 weeks. The OVX groups exhibited significantly more weight gain, amounts of bone turnover biochemical markers (alkaline phosphatase, osteocalcin, and C-terminal telopeptide), bone loss, lipid-peroxidation and oxidative stress than the SHAM group. However, Superjami bran extract added to the diet resulted in a significant reduction in body weight and lipid peroxidation, as well as enhanced bone metabolism and antioxidant enzyme activities, in ovariectomized rats. These results propound that extracts from Superjami rice bran have therapeutic potentiality against bone loss and oxidative stress in menopause-induced states and will be useful in preventing postmenopausal osteoporosis and oxidative damage.

scholarly journals Rice bran protein hydrolysates reduce arterial stiffening, vascular remodeling and oxidative stress in rats fed a high-carbohydrate and high-fat diet

2016 ◽  
Vol 57 (1) ◽  
pp. 219-230 ◽  
Author(s):  
Ketmanee Senaphan ◽  
Weerapon Sangartit ◽  
Poungrat Pakdeechote ◽  
Veerapol Kukongviriyapan ◽  
Patchareewan Pannangpetch ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Rice Bran ◽  
High Fat Diet ◽  
Vascular Remodeling ◽  
Protein Hydrolysates ◽  
High Fat ◽  
Arterial Stiffening ◽  
Rice Bran Protein ◽  
High Carbohydrate ◽  
And Oxidative Stress

scholarly journals Inhibition of Oxidative Stress through the Induction of Antioxidant Enzymes of Pigmented Rice Bran in HEK-293 Cells

2017 ◽  
Vol 12 (7) ◽  
pp. 1934578X1701200 ◽  
Author(s):  
Ruksinee Khammanit ◽  
Pattamapan Lomarat ◽  
Natthinee Anantachoke ◽  
Vilasinee H. Sato ◽  
Malyn Ungsurungsie ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Enzymes ◽  
Rice Bran ◽  
Antioxidant Property ◽  
Ros Generation ◽  
Hek 293 ◽  
Hek 293 Cells ◽  
Glutathione Peroxidase 1 ◽  
Pigmented Rice ◽  
293 Cells

The cellular antioxidant enzymes play an essential role on the protection of oxidative stress. Pigmented rice bran is the major sources of phytochemicals and elicits antioxidant property. However, the effects of pigmented rice bran on the upregulation of cellular antioxidant enzymes are incompletely understood. In this study, we demonstrated that treatment of HEK-293 cells with pigmented rice bran extracts (200 μg/mL) from Red Hawm, Red Rose, Black Sukhothai-II, and Kum Doisaket strains significantly inhibited H2O2-induced intracellular ROS production. These pigmented rice bran extracts induced mRNA expression of glutathione peroxidase-1 (GPx-1), glutathione reductase and catalase. Additionally, treatment with these rice bran extract also increased protein expression of GPx-1 and catalase. Thus, these pigmented rice bran extracts exert the cellular antioxidant effects by decreasing ROS generation as well as increasing the production of antioxidant enzymes.

scholarly journals Rice bran modulates renal disease risk factors in animals submitted to high sugar-fat diet

2021 ◽  
Author(s):  
Juliana Silva Siqueira ◽  
Fabiane Valentini Francisqueti-Ferron ◽  
Jéssica Leite Garcia ◽  
Carol Cristina Vágula de Almeida Silva ◽  
Mariane Róvero Costa ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Risk Factors ◽  
Renal Function ◽  
Renal Disease ◽  
Rice Bran ◽  
Disease Risk ◽  
Stress Protein ◽  
High Sugar ◽  
Male Wistar Rats ◽  
And Oxidative Stress

Abstract Introduction: Obesity, diabetes, and hypertension are common risk factors for chronic kidney disease (CKD). CKD arises due to many pathological insults, including inflammation and oxidative stress, which affect renal function and destroy nephrons. Rice bran (RB) is rich in vitamins and minerals, and contains significant amount of antioxidants. The aim of this study was to evaluate the preventive effect of RB on renal disease risk factors. Methods: Male Wistar rats (±325 g) were divided into two experimental groups to received a high sugar-fat diet (HSF, n = 8) or high sugar-fat diet with rice bran (HSF + RB, n = 8) for 20 weeks. At the end, renal function, body composition, metabolic parameters, renal inflammatory and oxidative stress markers were analyzed. Results: RB prevented obesity [AI (HSF= 9.92 ± 1.19 vs HSF + RB= 6.62 ± 0.78)ENT#093;, insulin resistance [HOMA (HSF= 83 ± 8 vs. HSF + RB= 42 ± 11)ENT#093;, dyslipidemia [TG (HSF= 167 ± 41 vs. HSF + RB=92 ± 40)ENT#093;, inflammation [TNF-α (HSF= 80 ± 12 vs. HSF + RB=57 ± 14), IL-6 (903 ± 274 vs. HSF + RB=535 ± 277)], oxidative stress [protein carbonylation (HSF= 3.38 ± 0.18 vs. HSF + RB=2.68 ± 0.29), RAGE (HSF=702 ± 36 vs. RSF + RB=570 ± 190)], and renal disease [protein/creatinine ratio (HSF=1.10 ± 0.38 vs. HSF + RB=0.49 ± 0.16)]. Conclusion: In conclusion, rice bran prevented renal disease by modulating risk factors.

Association between calcitriol and paricalcitol with oxidative stress in patients with hemodialysis

2020 ◽  
pp. 1-8
Author(s):  
Hasan Haci Yeter ◽  
Berfu Korucu ◽  
Elif Burcu Bali ◽  
Ulver Derici
Keyword(s):  
Oxidative Stress ◽  
Vitamin D ◽  
Antioxidant Status ◽  
Total Antioxidant Status ◽  
Stress Index ◽  
Total Oxidant Status ◽  
Vitamin D Analog ◽  
Total Antioxidant ◽  
Oxidant Status ◽  
And Oxidative Stress

Abstract. Background: The pathophysiological basis of chronic kidney disease and its complications, including cardiovascular disease, are associated with chronic inflammation and oxidative stress. We investigated the effects of active vitamin D (calcitriol) and synthetic vitamin D analog (paricalcitol) on oxidative stress in hemodialysis patients. Methods: This cross-sectional study was composed of 83 patients with a minimum hemodialysis vintage of one year. Patients with a history of any infection, malignancy, and chronic inflammatory disease were excluded. Oxidative markers (total oxidant and antioxidant status) and inflammation markers (C-reactive protein and interleukin-6) were analyzed. Results: A total of 47% (39/83) patients were using active or analog vitamin D. Total antioxidant status was significantly higher in patients with using active or analog vitamin D than those who did not use (p = 0.006). Whereas, total oxidant status and oxidative stress index were significantly higher in patients with not using vitamin D when compared with the patients who were using vitamin D preparation (p = 0.005 and p = 0.004, respectively). On the other hand, total antioxidant status, total oxidant status, and oxidative stress index were similar between patients who used active vitamin D or vitamin D analog (p = 0.6; p = 0.4 and p = 0.7, respectively). Conclusion: The use of active or selective vitamin D analog in these patients decreases total oxidant status and increases total antioxidant status. Also, paricalcitol is as effective as calcitriol in decreasing total oxidant status and increasing total antioxidant status in patients with chronic kidney disease.

Sign in / Sign up

Export Citation Format

Share Document