Multiobjective Optimization of Total Monomeric Anthocyanins and Total Flavonoids Contents in Ultrasound-Assisted Extraction from Purple Potato Tubers

2016 ◽  
Vol 40 (3) ◽  
pp. e12422 ◽  
Author(s):  
Alexandru Woinaroschy ◽  
Florentina Damşa
2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Ling-Li Zheng ◽  
Guan Wen ◽  
Min-Yong Yuan ◽  
Feng Gao

Object. Ultrasound-assisted extraction of total flavonoids from corn silk and their antioxidant activities were studied.Methods. Response surface methodology was adopted to optimize the extraction conditions and antioxidant activities of the extracted total flavonoids were detected through ferric reducing antioxidant power (FRAP) assay.Results. Through a three-level, three-variable Box-Behnken design of response surface methodology (RSM) adopting yield as response, the optimal conditions were determined as follows: ultrasonic power 500 W, extraction time 20 min, material solvent ratio 1 : 20, and ethanol concentration 30%. Under the optimum conditions, the extraction yield of total flavonoids was 1.13%. FRAP value of total flavonoids extracted from corn silk was 467.59 μmol/L.Conclusion. The total flavonoids of corn silk could be developed as food natural antioxidant reagents.


Molecules ◽  
2020 ◽  
Vol 25 (8) ◽  
pp. 1767 ◽  
Author(s):  
Sanhong Fan ◽  
Gege Yang ◽  
Jinhua Zhang ◽  
Jiani Li ◽  
Baoqing Bai

Ultrasound-assisted extraction (UAE) was applied to extract rutin (RU), nicotiflorin (NI), narcissoside (NA), kaempferol (KA), isorhamnetin (IS), quercetin (QU), and total flavonoids of Flos Sophorae Immaturus (TFFSI) from Flos Sophorae Immaturus (FSI). Through single factor test and response surface methodology (RSM), the optimal extraction conditions were concluded as follows: ethanol concentration 70%, time 30 min, temperature 61 °C, and liquid/solid ratio 15.30 mL/g, respectively. The actual extraction rates of RU, NI, NA, KA, IS, QU, and TFFSI were 14.6101%, 2.9310%, 7.1987%, 0.1041%, 0.4920%, 2.7998%, and 26.4260%, respectively. The experimental results demonstrated that the extraction method with accuracy and efficiency could be used for the comprehensive evaluation quality control of extracts from FSI. The antioxidant activities of hydroalcoholic extraction from FSI on 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS•+), superoxide anion (•O2−) free radicals, and ferric reducing/antioxidant power (FRAP) were assessed. The results showed that the antioxidation activities of extracts on DPPH, ABTS•+, and •O2− free radicals were reached 89.29%, 97.86%, and 56.61%, and 81.4% in FRAP at 1.0 mg/mL, respectively. The antioxidant capacity of FSI extract was positively correlated with the amount of total flavonoids.


2014 ◽  
Vol 900 ◽  
pp. 267-274 ◽  
Author(s):  
Jie Wei ◽  
Jia Shi ◽  
Jun Gao ◽  
Zhi Quan Zhou ◽  
Jun Gang Fan

Sorbus sibirica fruits, popularly consumed as tea, is believed to promote healthy, relieve a cough. The literature reporting pharmacological studies related to Sorbus sibirica is very limited. Thus, The antioxidant activities of extracts from Sorbus sibirica fruits were evaluated using various in vitro assays including total flavonoid contents, total antioxidant activity, reducing power, lipid peroxidation inhibitory activity, scavenging hydroxyl and superoxide anion free radicals activity, and protective effects against DNA and protein damages. We selected the process of ultrasound-assisted extraction for total flavonoids from Sorbus sibirica fruits according to the extraction rate of total flavonoids. Results showed that the content of total flavonoids was 0.82 g per 100 g dry fruits sample obtained with ultrasound-assisted extraction method. The extracts exhibited strong scavenging capability with respect to hydroxyl and superoxide anion free radicals, and effectively inhibited the lipid peroxidation of polyunsaturated fatty acids. They also had good reducing power and protection against DNA and protein damage. Therefore, they might offer an important source of effective natural antioxidants in the food and cosmetic industries.


2012 ◽  
Vol 8 (30) ◽  
pp. 166 ◽  
Author(s):  
Dan-Shen Zhang ◽  
Jin Wang ◽  
Chun-Yan Guo ◽  
Shao-Meng Zhang ◽  
Chun-Lei Liu ◽  
...  

2019 ◽  
Vol 2019 ◽  
pp. 1-10
Author(s):  
Lijie Zhong ◽  
Yi Liu ◽  
Bin Xiong ◽  
Lin Chen ◽  
Yaohua Zhang ◽  
...  

Dendranthema indicum var. aromaticum is a new species with strong fragrance and is used as a herbal medicine by Chinese folks. The abundant flavonoids play important roles in its pharmacological activities. In this study, an ultrasound-assisted method was used to extract total flavonoids (TF) from D. indicum var. aromaticum by response surface methodology. A quadratic model was developed to optimize the extraction conditions, whose accuracy was verified by statistic analysis. Ethanol and acetic acid at the volume ratio of 70% : 2% were selected as the extract solvent. The optimized extraction conditions were as follows: extraction time, 40 min; solid/liquid ratio, 1 : 23 g/mL; and temperature, 60°C. This is the first report of an efficient and easy-operating method for TF extraction from D. indicum var. aromaticum. Besides, this study provides reference for future pharmacological research on D. indicum var. aromaticum and extraction of bioactive components from other herbs.


2014 ◽  
Vol 10 (37) ◽  
pp. 141 ◽  
Author(s):  
Feng Gao ◽  
Ling-Li Zheng ◽  
Dan Wang ◽  
Yuan-Yuan Li ◽  
Hong-Yan Peng ◽  
...  

2014 ◽  
Vol 44 (2) ◽  
pp. 131-135
Author(s):  
Z. SHENG ◽  
Y. WANG ◽  
P. WAN ◽  
Y. LI

Leaves of Syringa Oblata Lindl. possess some important biological activities, such as antibacterial, antiviral, anti-inflammatory and antioxidant activities. These biological properties are mainly attributed to total flavonoids content. In this paper, ultrasound-assisted extraction of total flavonoids from leaves of Syringa Oblata Lindl. was studied. Effects of several experimental parameters, such as concentration of extracting solvent, ratio of liquid to material, extraction temperature, and time of sonication on extraction efficiencies of total flavonoids were evaluated. The best extraction conditions were: 1 g plant sample with 20 mL of 50% ethanol, at 60 °C for 50 min, obtaining a yield of total flavonoids of 92.00 ± 0.87 mg/g of plant. The results indicated that high amounts of total flavonoids can be extracted from leaves of Syringa Oblata Lindl. by ultrasound-assisted extraction technology.


Separations ◽  
2021 ◽  
Vol 8 (9) ◽  
pp. 155
Author(s):  
Anita Milić ◽  
Tatjana Daničić ◽  
Aleksandra Tepić Horecki ◽  
Zdravko Šumić ◽  
Danijela Bursać Kovačević ◽  
...  

Sour cherries were first dried by vacuum drying and then used as material for obtaining extracts rich in bioactive compounds by ultrasound-assisted extraction (UAE). The first step was to apply a factorial design for the preliminary experiments to determine the most influential UAE factors, and thus the three studied parameters were chosen as the most suitable for the design of the main experiment (temperature, liquid–solid ratio and ethanol concentration). In this part, the contents of total phenols and the total content of monomeric anthocyanins were taken for responses. For the further optimization of UAE, experimental design (face-centered) was applied, and the yield, total phenolics, flavonoid content and content of monomeric anthocyanins and antioxidant activity (DPPH, ABTS and FRAP assays) were analyzed. Temperature (40–80 °C), ethanol concentration (40–80%, w/w) and liquid–solid ratio (10–30 mL/g) were investigated as independent variables. The obtained experimental results were fitted to a second-order polynomial model and analysis of variance was used to determine the fit of the model and the optimal conditions for investigated responses. High quality extracts with high concentrations of polyphenols and anthocyanins were also obtained, which could be used as food additives.


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