C-reactive protein/albumin ratio is a poor prognostic factor of esophagogastric junction and upper gastric cancer

2018 ◽  
Vol 34 (2) ◽  
pp. 355-363 ◽  
Author(s):  
Kensuke Kudou ◽  
Hiroshi Saeki ◽  
Yuichiro Nakashima ◽  
Tomohiro Kamori ◽  
Tetsuro Kawazoe ◽  
...  
2019 ◽  
Vol 15 (19) ◽  
pp. 2277-2286 ◽  
Author(s):  
Qiuju Wang ◽  
Xiaoyu Song ◽  
Yanzhen Zhao ◽  
Qiao He ◽  
Min Shi ◽  
...  

2019 ◽  
Vol 37 (11) ◽  
pp. 812.e1-812.e8 ◽  
Author(s):  
Takuya Tsujino ◽  
Kazumasa Komura ◽  
Takeshi Hashimoto ◽  
Ryu Muraoka ◽  
Naoya Satake ◽  
...  

Medicine ◽  
2020 ◽  
Vol 99 (10) ◽  
pp. e19362
Author(s):  
Xuanxuan Yang ◽  
Xing Song ◽  
Luo Zhang ◽  
Changping Wu

2017 ◽  
Vol 225 (4) ◽  
pp. S187
Author(s):  
Yuji Toiyama ◽  
Yasuhiko Mohri ◽  
Tadanobu Shimura ◽  
Hiromi Yasuda ◽  
Hiroyuki Fujikawa ◽  
...  

2013 ◽  
Vol 31 (4_suppl) ◽  
pp. 110-110 ◽  
Author(s):  
Mika Kitagawa ◽  
Takaya Shimura ◽  
Tomonori Yamada ◽  
Keisuke Itoh ◽  
Chihiro Hasegawa ◽  
...  

110 Background: S-1 plus cisplatin has been recognized as the standard chemotherapy for metastatic gastric cancer (MGC). Inflammation is considered to be a critical component of tumor progression. C-reactive protein (CRP) has been associated with the development of many cancers, but the significance of CRP remains unclear for MGC. The present study assessed the relationship between serum levels CRP and antitumor effects in MGC. Methods: Among 109 MGC patients who received S-1 plus cisplatin as first-line chemotherapy from January 2006 to December 2011 in 3 Japanese institutions, we retrospectively identified 70 patients who fulfilled eligibility criteria of this study. Patients were categorized into 2 groups depending on serum CRP level before chemotherapy: 43 patients with CRP <1.0 mg/dl (CRP <1.0 group) and 27 patients with CRP ≥1.0 mg/dl (CRP ≥1.0 group). Results: Median overall survival was significantly shorter in the CRP ≥1.0 group than in the CRP <1.0 group [267 days (95% CI, 208 to 326) versus 416 days (95% CI, 325 to 507); p = 0.0007]. Moreover, progression-free survival (PFS) was significantly shorter in the CRP ≥1.0 group than in the CRP <1.0 group (median PFS 126 days [95% CI, 63 to 189) versus 188 days (95% CI, 159 to 217); p = 0.0050]. Meanwhile, response rate was determined in 58 patients with target lesions. No significant differences were noted between the CRP <1.0 group and the CRP ≥1.0 group (10/33, 30.3% versus 7/25, 28.0%; p = 0.663). In a multivariate analysis, serum CRP level before chemotherapy was an only independent prognostic factor for MGC (hazard ratio 3.09 (95% CI, 1.46 to 6.54); p = 0.003). Conclusions: Serum CRP level before chemotherapy might be an independent and potential prognostic factor for MGC. Stringent follow-up during chemotherapy is expected for patients with MGC and a high CRP level.


Author(s):  
Ozlem Zeliha Sert ◽  
Hilmi Bozkurt ◽  
Ibrahim Can Bulut ◽  
Orhan Uzun ◽  
Selcuk Gulmez ◽  
...  

2015 ◽  
Vol 8 (4) ◽  
pp. 339-345 ◽  
Author(s):  
Xuechao Liu ◽  
Xiaowei Sun ◽  
Jianjun Liu ◽  
Pengfei Kong ◽  
Shangxiang Chen ◽  
...  

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