Comparison of perinatal outcomes between long-term and short-term use of tocolytic agent: a historical cohort study in a single perinatal hospital

2016 ◽  
Vol 42 (12) ◽  
pp. 1680-1685 ◽  
Author(s):  
Masamitsu Nakamura ◽  
Junichi Hasegawa ◽  
Tatsuya Arakaki ◽  
Shoko Hamada ◽  
Hiroko Takita ◽  
...  
Author(s):  
Emanuele Durante-Mangoni ◽  
Giuseppe Giuffrè ◽  
Maria Paola Ursi ◽  
Domenico Iossa ◽  
Lorenzo Bertolino ◽  
...  

2019 ◽  
Vol 2019 ◽  
pp. 1-6 ◽  
Author(s):  
James M. Edwards ◽  
Nora Watson ◽  
Chris Focht ◽  
Clara Wynn ◽  
Christopher A. Todd ◽  
...  

Background. Maternal GBS colonization is associated with early-onset neonatal sepsis and extensive efforts are directed to preventing this complication. Less is known about maternal risks of GBS colonization. We seek to provide a modern estimate of the incidence and impact of maternal GBS colonization and invasive GBS disease. Methods. A single center historical cohort study of all births between 2003 and 2015 was performed. Data was collected via electronic health record abstraction using an institutional specific tool. Descriptive statistics were performed regarding GBS status. Inferential statistics were performed comparing risk of adverse pregnancy outcomes in cohorts with and without GBS colonization as well as cohorts with GBS colonization and invasive GBS disease. Results. A total of 60,029 deliveries were included for analysis. Overall, 21.6% of the population was GBS colonized and 0.1% had invasive GBS disease. GBS colonization was associated with younger maternal age, Black race, non-Hispanic ethnicity, chronic hypertension, preexisting diabetes, and tobacco use (p<0.01). In the adjusted analyses, there was an increased risk of gestational diabetes (aRR 1.21, 95% CI 1.11-1.32) in colonized pregnancies and a decreased incidence of short cervix (aRR 0.64, 95% CI 0.52-0.79), chorioamnionitis (aRR 0.76, 95% CI 0.66-0.87), wound infection (aRR 0.75, 95% CI 0.64-0.88), and operative delivery (aRR 0.85, 95% CI 0.83-0.88). Conclusions. This modern-day large cohort of all births over a 12-year period demonstrates a GBS colonization rate of 21.6%. This data reflects a need to assess maternal and perinatal outcomes in addition to neonatal GBS sepsis rates to inform decisions regarding the utility of maternal vaccination.


2016 ◽  
Vol 263 (6) ◽  
pp. 1120-1128 ◽  
Author(s):  
Nete Munk Nielsen ◽  
Lise Kay ◽  
Benedikte Wanscher ◽  
Rikke Ibsen ◽  
Jakob Kjellberg ◽  
...  

Author(s):  
Cécile Marie ◽  
Céline Sinoquet ◽  
Chloé Barasinski ◽  
Didier Lémery ◽  
Françoise Vendittelli

2019 ◽  
Vol 26 (12) ◽  
pp. 1479-1486 ◽  
Author(s):  
J. Gregson ◽  
N. Qizilbash ◽  
M. Iwagami ◽  
I. Douglas ◽  
M. Johnson ◽  
...  

PLoS ONE ◽  
2019 ◽  
Vol 14 (7) ◽  
pp. e0219294
Author(s):  
Liva Helleland ◽  
Lena Flekke Bergesen ◽  
Karen Jakobsen Rinnan ◽  
Ingeborg Bøe Engelsen ◽  
Knut Hordnes ◽  
...  

2021 ◽  
Author(s):  
Mehak Pahwa ◽  
Boney Joseph ◽  
Nicolas A. Nunez ◽  
Gregory D. Jenkins ◽  
Colin L. Colby ◽  
...  

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