Inflammatory and metabolic responses to an intramammary lipopolysaccharide challenge in early lactating cows supplemented with conjugated linoleic acid

2017 ◽  
Vol 102 (2) ◽  
pp. e838-e848 ◽  
Author(s):  
J. J. Gross ◽  
L. Grossen-Rösti ◽  
R. Héritier ◽  
A. Tröscher ◽  
R. M. Bruckmaier
Keyword(s):  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Metabolic Responses ◽  
Lactating Cows ◽  
Lipopolysaccharide Challenge

Lactation response of cows to different levels of ruminally inert conjugated linoleic acids under commercial conditions

2005 ◽  
Vol 85 (2) ◽  
pp. 231-242 ◽  
Author(s):  
Rachel Gervais ◽  
Richard Spratt ◽  
Martin Léonard ◽  
P. Yvan Chouinard
Keyword(s):  
Linoleic Acid ◽  
Dairy Cows ◽  
Conjugated Linoleic Acid ◽  
Milk Production ◽  
Milk Fat ◽  
Metabolic Profile ◽  
Milk Composition ◽  
Dietary Lipids ◽  
Calcium Salts ◽  
Lactating Cows

Dietary conjugated linoleic acid (CLA) supplements have been shown to reduce milk fat synthesis in dairy cows. A rumen-inert source of CLA is required for commercial feed applications. The conversion of dietary lipids to a calcium salt is considered as a method to counter the extensive hydrogenation of dietary lipids that occurs in the rumen. Our objective was to determine whether feeding calcium salts of CLA under commercial conditions would affect milk production, milk composition and blood metabolic profile. A total of 240 dairy cows from eight farms were blocked according to the calving date, and randomly assigned to four treatments providing CLA at 0, 8, 16 and 32 g d-1. Milk production was recorded and milk was sampled on day 0, 7, 14, 28 and 42 of the feeding period. Blood samples were taken on day 42 from early-lactating cows (< 157 d in milk) to determine the metabolic profile. Milk fat yield was decreased 11, 20 and 28%, and milk fat concentration was reduced 13, 22 and 28% (linear; P < 0.001) when cows received 8, 16 and 32 g d-1 of CLA, respectively. Milk yield, milk protein and blood metabolic parameters were not affected by experimental treatments. Calcium salts of CLA can be used as an effective tool to manage milk fat content on commercial dairy farms. Key words: Conjugated linoleic acid, milk fat, ruminally inert fat

scholarly journals Effect of Intake of Pasture on Concentrations of Conjugated Linoleic Acid in Milk of Lactating Cows

1998 ◽  
Vol 81 (6) ◽  
pp. 1630-1636 ◽  
Author(s):  
M.L. Kelly ◽  
E.S. Kolver ◽  
D.E. Bauman ◽  
M.E. Van Amburgh ◽  
L.D. Muller
Keyword(s):  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Lactating Cows

Influence of roughage/concentrate ratio and linseed oil on the concentration oftrans-fatty acids and conjugated linoleic acid in duodenal chyme and milk fat of late lactating cows

2006 ◽  
Vol 60 (6) ◽  
pp. 501-511 ◽  
Author(s):  
Gerhard Flachowsky ◽  
Kristin Erdmann ◽  
Liane Hüther ◽  
Gerhard Jahreis ◽  
Peter Möckel ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Milk Fat ◽  
Linseed Oil ◽  
Lactating Cows

Conjugated Linoleic Acid Causes a Marked Increase in Liver α-Tocopherol and Liver α-Tocopherol Transfer Protein in C57BL/6 J Mice

2010 ◽  
Vol 80 (1) ◽  
pp. 65-73 ◽  
Author(s):  
Pei-Min Chao ◽  
Wan-Hsuan Chen ◽  
Chun-Huei Liao ◽  
Huey-Mei Shaw
Keyword(s):  
Antioxidant Enzymes ◽  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Thiobarbituric Acid ◽  
Control Group ◽  
Thiobarbituric Acid Reactive Substances ◽  
Control Groups ◽  
Protein Levels ◽  
Transfer Protein ◽  
And Control

Conjugated linoleic acid (CLA) is a collective term for the positional and geometric isomers of a conjugated diene of linoleic acid (C18:2, n-6). The aims of the present study were to evaluate whether levels of hepatic α-tocopherol, α-tocopherol transfer protein (α-TTP), and antioxidant enzymes in mice were affected by a CLA-supplemented diet. C57BL/6 J mice were divided into the CLA and control groups, which were fed, respectively, a 5 % fat diet with or without 1 g/100 g of CLA (1:1 mixture of cis-9, trans-11 and trans-10, cis-12) for four weeks. α-Tocopherol levels in plasma and liver were significantly higher in the CLA group than in the control group. Liver α-TTP levels were also significantly increased in the CLA group, the α-TTP/β-actin ratio being 2.5-fold higher than that in control mice (p<0.01). Thiobarbituric acid-reactive substances were significantly decreased in the CLA group (p<0.01). There were no significant differences between the two groups in levels of three antioxidant enzymes (superoxide dismutase, glutathione peroxidase, and catalase). The accumulation of liver α-tocopherol seen with the CLA diet can be attributed to the antioxidant potential of CLA and the ability of α-TTP induction. The lack of changes in antioxidant enzyme protein levels and the reduced lipid peroxidation in the liver of CLA mice are due to α-tocopherol accumulation.

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