scholarly journals An in vitro biofilm model system to facilitate study of microbial communities of the human oral cavity

2021 ◽  
Author(s):  
Shi‐qi An ◽  
Robert Hull ◽  
Aline Metris ◽  
Paul Barrett ◽  
Jeremy Webb ◽  
...  
Keyword(s):  
Oral Cavity ◽  
Microbial Communities ◽  
Model System ◽  
Human Oral Cavity ◽  
Biofilm Model

In vitro cytotoxicity of a theaflavin mixture from black tea to malignant, immortalized, and normal cells from the human oral cavity

2006 ◽  
Vol 20 (5) ◽  
pp. 677-688 ◽  
Author(s):  
H. Babich ◽  
S.M. Pinsky ◽  
E.T. Muskin ◽  
H.L. Zuckerbraun
Keyword(s):  
Oral Cavity ◽  
Black Tea ◽  
In Vitro Cytotoxicity ◽  
Normal Cells ◽  
Human Oral Cavity

In Vitro Studies on the Responses of Healthy and Cancerous Cells Derived from Tissues of the Human Oral Cavity to Tea Theaflavins and Catechins

2013 ◽  
pp. 871-882
Author(s):  
Harvey Babich ◽  
Harriet L. Zuckerbraun ◽  
Alyssa G. Schuck ◽  
Jeffrey H. Weisburg
Keyword(s):  
Oral Cavity ◽  
In Vitro Studies ◽  
Human Oral Cavity ◽  
Cancerous Cells

scholarly journals In Vivo Drug Dissolution in Human Oral Cavity from Orally Disintegrating Tablet and Comparability with in Vitro Testing

2018 ◽  
Vol 66 (10) ◽  
pp. 999-1005 ◽  
Author(s):  
Tsuyoshi Katayama ◽  
Shinya Uchida ◽  
Chiaki Kamiya ◽  
Shimako Tanaka ◽  
Yasuharu Kashiwagura ◽  
...  
Keyword(s):  
Oral Cavity ◽  
Drug Dissolution ◽  
Orally Disintegrating Tablet ◽  
Human Oral Cavity

scholarly journals An in vitro biofilm model system maintaining a highly reproducible species and metabolic diversity approaching that of the human oral microbiome

Microbiome ◽  
2013 ◽  
Vol 1 (1) ◽  
pp. 25 ◽  
Author(s):  
Anna Edlund ◽  
Youngik Yang ◽  
Adam P Hall ◽  
Lihong Guo ◽  
Renate Lux ◽  
...  
Keyword(s):  
Model System ◽  
Oral Microbiome ◽  
Metabolic Diversity ◽  
Biofilm Model

In vitro labelling studies and the measurement of epithelial cell proliferative activity in the human oral cavity

2001 ◽  
Vol 46 (12) ◽  
pp. 1157-1164 ◽  
Author(s):  
P.J Thomson ◽  
C.S Potten ◽  
D.R Appleton
Keyword(s):  
Epithelial Cell ◽  
Oral Cavity ◽  
Proliferative Activity ◽  
Human Oral Cavity ◽  
Cell Proliferative Activity

Differential in vitro cytotoxicity of (−)-epicatechin gallate (ECG) to cancer and normal cells from the human oral cavity

2005 ◽  
Vol 19 (2) ◽  
pp. 231-242 ◽  
Author(s):  
H. Babich ◽  
M.E. Krupka ◽  
H.A. Nissim ◽  
H.L. Zuckerbraun
Keyword(s):  
Oral Cavity ◽  
In Vitro Cytotoxicity ◽  
Epicatechin Gallate ◽  
Normal Cells ◽  
Human Oral Cavity

scholarly journals Antimicrobial activity of Uncaria tomentosa against oral human pathogens

2007 ◽  
Vol 21 (1) ◽  
pp. 46-50 ◽  
Author(s):  
Renzo Alberto Ccahuana-Vasquez ◽  
Silvana Soléo Ferreira dos Santos ◽  
Cristiane Yumi Koga-Ito ◽  
Antonio Olavo Cardoso Jorge
Keyword(s):  
Antimicrobial Activity ◽  
Oral Cavity ◽  
Inhibitory Effect ◽  
Human Pathogens ◽  
Uncaria Tomentosa ◽  
Human Oral Cavity ◽  
Mueller Hinton Agar ◽  
Different Strains ◽  
Staphylococcus Spp

Uncaria tomentosa is considered a medicinal plant used over centuries by the peruvian population as an alternative treatment for several diseases. Many microorganisms usually inhabit the human oral cavity and under certain conditions can become etiologic agents of diseases. The aim of the present study was to evaluate the antimicrobial activity of different concentrations of Uncaria tomentosa on different strains of microorganisms isolated from the human oral cavity. Micropulverized Uncaria tomentosa was tested in vitro to determine the minimum inhibitory concentration (MIC) on selected microbial strains. The tested strains were oral clinical isolates of Streptococcus mutans, Staphylococcus spp., Candida albicans, Enterobacteriaceae and Pseudomonas aeruginosa. The tested concentrations of Uncaria tomentosa ranged from 0.25-5% in Müeller-Hinton agar. Three percent Uncaria tomentosa inhibited 8% of Enterobacteriaceae isolates, 52% of S. mutans and 96% of Staphylococcus spp. The tested concentrations did not present inhibitory effect on P. aeruginosa and C. albicans. It could be concluded that micropulverized Uncaria tomentosa presented antimicrobial activity on Enterobacteriaceae, S. mutans and Staphylococcus spp. isolates.

scholarly journals Microbial biogeography and ecology of the mouth and implications for periodontal diseases

2019 ◽  
Author(s):  
Diana M. Proctor ◽  
Katie M. Shelef ◽  
Antonio Gonzalez ◽  
Clara L. Davis Long ◽  
Les Dethlefsen ◽  
...  
Keyword(s):  
Oral Cavity ◽  
Microbial Communities ◽  
Community Composition ◽  
Periodontal Diseases ◽  
Microbial Community Composition ◽  
Oral Microbiota ◽  
Biogeographic Patterns ◽  
Microbial Biogeography ◽  
Human Oral Cavity

AbstractHuman-associated microbial communities differ in composition among body sites and between habitats within a site. Patterns of variation in the distribution of organisms across time and space is referred to as ‘biogeography’. The human oral cavity is a critical observatory for exploring microbial biogeography because it is spatially structured, easily accessible, and its microbiota has been linked to the promotion of both health and disease. The biogeographic features of microbial communities residing in spatially distinct but ecologically similar environments on the human body, including the subgingival crevice, have not yet been adequately explored. The purpose of this paper is twofold. First, we seek to provide the dental community with a primer on biogeographic theory, highlighting its relevance to the study of the human oral cavity. For this reason, we summarize what is known about the biogeographic variation of dental caries and periodontitis and postulate as to how this may be driven by spatial patterning in oral microbial community composition and structure. Second, we present a number of methods that investigators can use to test specific hypotheses using biogeographic theory.To anchor our discussion, we apply each method to a case study and examine the spatial variation of the human subgingival microbiota of 2 individuals. Our case study suggests that subgingival communities in the aggregate may conform to an anterior-to-posterior gradient in community composition. The gradient appears to be structured both by deterministic and non-deterministic processes, though additional work is needed to test and confirm specific hypotheses. A better understanding of biogeographic patterns and processes will advance our understanding of ways to optimize the efficacy of dental interventions targeting the oral microbiota.

scholarly journals In vitro Cytotoxicity of Epigallocatechin Gallate and Tea Extracts to Cancerous and Normal Cells from the Human Oral Cavity

2004 ◽  
Vol 95 (4) ◽  
pp. 191-200 ◽  
Author(s):  
Jeffrey H. Weisburg ◽  
Danielle B. Weissman ◽  
Tannaz Sedaghat ◽  
Harvey Babich
Keyword(s):  
Oral Cavity ◽  
Epigallocatechin Gallate ◽  
In Vitro Cytotoxicity ◽  
Normal Cells ◽  
Human Oral Cavity

1642 Effect of Enterococcus fecalis SROD5 supplementation on microbial communities and quantities of in vitro rumen fermentation

2016 ◽  
Vol 94 (suppl_5) ◽  
pp. 800-800
Author(s):  
L. L. Mamuad ◽  
S. S. Lee ◽  
A. A. Biswas ◽  
C. D. Jeong
Keyword(s):  
Microbial Communities ◽  
Rumen Fermentation ◽  
In Vitro Rumen Fermentation
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