Clinical features of spinal epidural abscess mimicking Guillain‐Barré syndrome

2020 ◽  
Vol 8 (2) ◽  
pp. 103-104
Author(s):  
Syuichi Tetsuka ◽  
Tomohiro Suzuki ◽  
Hiroyuki Kato
Keyword(s):  
Clinical Features ◽  
Epidural Abscess ◽  
Guillain Barre Syndrome ◽  
Spinal Epidural Abscess ◽  
Guillain Barré Syndrome ◽  
Guillain Barré ◽  
Spinal Epidural

scholarly journals Campylobacter coli infection causes spinal epidural abscess with Guillain–Barré syndrome: a case report

BMC Neurology ◽  
2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Masako Fujita ◽  
Tatsuya Ueno ◽  
Michiru Horiuchi ◽  
Tatsuro Mitsuhashi ◽  
Shouji Yamamoto ◽  
...  
Keyword(s):  
Epidural Abscess ◽  
Immunoglobulin Therapy ◽  
Lower Limbs ◽  
Guillain Barre Syndrome ◽  
Campylobacter Coli ◽  
Spinal Epidural Abscess ◽  
First Case ◽  
Guillain Barré Syndrome ◽  
Guillain Barré ◽  
Spinal Epidural

Abstract Background Guillain–Barré syndrome (GBS) and spinal epidural abscess (SEA) are known as mimics of each other because they present with flaccid paralysis following an infection; however, they differ in the main causative bacteria. Nevertheless, the two diseases can occur simultaneously if there is a preceding Campylobacter infection. Here, we report the first case of SEA with GBS following Campylobacter coli infection. Case presentation A 71-year-old Japanese man presented with progressive back pain and paralysis of the lower limbs following enteritis. Magnetic resonance imaging showed a lumbar epidural abscess that required surgical decompression; therefore, surgical drainage was performed. Blood cultures revealed the presence of C. coli. Despite surgery, the paralysis progressed to the extremities. Nerve conduction studies led to the diagnosis of GBS. Anti-ganglioside antibodies in the patient suggested that GBS was preceded by Campylobacter infection. Intravascular immunoglobulin therapy attenuated the progression of the paralysis. Conclusions We report a case of SEA and GBS following Campylobacter infection. A combination of the two diseases is rare; however, it could occur if the preceding infection is caused by Campylobacter spp. If a cause is known but the patient does not respond to the corresponding treatment, it is important to reconsider the diagnosis based on the medical history.

scholarly journals Froin's syndrome mimicking Guillain–Barre syndrome in a patient with spinal epidural abscess

2019 ◽  
Vol 14 (1) ◽  
pp. 338
Author(s):  
LuisRafael Moscote-Salazar ◽  
AndreiF Joaquim ◽  
Gabriel Alcala-Cerra ◽  
Amit Agrawal ◽  
WillemGuillermo Calderon-Miranda
Keyword(s):  
Epidural Abscess ◽  
Guillain Barre Syndrome ◽  
Spinal Epidural Abscess ◽  
Guillain Barré Syndrome ◽  
Guillain Barré ◽  
Spinal Epidural

scholarly journals Guillain-Barré syndrome triggered by surgery in a Chinese population: a multicenter retrospective study

BMC Neurology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Qiaoyu Gong ◽  
Shuping Liu ◽  
Yin Liu ◽  
Jiajia Yao ◽  
Xiujuan Fu ◽  
...  
Keyword(s):  
Clinical Features ◽  
Orthopedic Surgery ◽  
Southern China ◽  
Axonal Neuropathy ◽  
Trigger Factor ◽  
Guillain Barre Syndrome ◽  
Initial Symptoms ◽  
Guillain Barré Syndrome ◽  
Potential Trigger ◽  
Guillain Barré

Abstract Background Surgery is a potential trigger of Guillain-Barré syndrome (GBS), a disorder which leads to an autoimmune-mediated attack of peripheral nerves. The present study was designed to explore clinical features of post-surgical GBS compared with those of general GBS in order to provide better clinical advice to patients undergoing surgery. Methods The medical records of GBS patients who were seen at 31 tertiary hospitals in southern China between January 1, 2013 and September 30, 2016 were retrospectively analyzed. Post-surgical GBS was defined as symptoms of GBS within 6 weeks after surgery. Clinical features of post-surgical GBS are described and are compared with general GBS. Results Among the 1001 GBS patient cases examined in this study, 45 (4.5%) patient cases exhibited symptoms of GBS within 6 weeks of undergoing surgery. Within this group, 36 (80.0%) patients developed initial symptoms of limb weakness. The average interval between surgery and symptom onset was 13.31 days. The most common type of surgery which triggered GBS was orthopedic surgery, followed by neurological surgery. Compared to general GBS, post-surgical GBS was characterized by a higher proportion of severe patients (Hughes functional grading scale (HFGS) score ≥ 3) upon admission and at nadir, higher HFGS scores at discharge, and longer hospital stays. Post-surgical GBS patients also had a significantly higher frequency of the acute motor axonal neuropathy subtype (37.9 vs. 14.2, respectively; P = 0.001). Conclusion Surgery is probably a potential trigger factor for GBS, especially orthopedic surgery. Infections secondary to surgery may play a role. The possibility of preceding (post-operative) infections was not excluded in this study. Clinical presentation of post-surgical GBS is characterized by a more severe course and poorer prognosis, and should be closely monitored. Trial registration chicTR-RRc-17,014,152.

scholarly journals Clinical features and prognosis with Guillain-Barré syndrome

2011 ◽  
Vol 14 (2) ◽  
pp. 98 ◽  
Author(s):  
Sinan Akbayram ◽  
Cihangir Akgün ◽  
Refah Sayin ◽  
Mehmet-Selçuk Bektas ◽  
Murat Dogan ◽  
...  
Keyword(s):  
Clinical Features ◽  
Guillain Barre Syndrome ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

scholarly journals Guillain-Barre syndrome- Rationale for physiotherapy management of the acute severe patient

1996 ◽  
Vol 52 (4) ◽  
pp. 85-87 ◽  
Author(s):  
Lynn Fearnhead ◽  
Vivian U. Fritz
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Supportive Care ◽  
Clinical Features ◽  
Guillain Barre Syndrome ◽  
Critical Importance ◽  
Guillain Barré Syndrome ◽  
Guillain Barré ◽  
Severe Patient

The critical importance of supportive care including physiotherapy to the acute severe Guillain-Barre patient is emphasised in numerous reports in the literature. However, there are no systematic studies of physiotherapy in Guillain-Barre syndrome (GBS). This article examines the aetiology, pathology, clinical features, prognosis and treatment of GBS with reference to the physiotherapists’ management of the acute severe patient treated in an intensive care unit.

HyperCKemia in Guillain-Barré Syndrome

2020 ◽  
Vol 83 (4) ◽  
pp. 415-420
Author(s):  
Seok-Jin Choi ◽  
Yoon-Ho Hong ◽  
Jun-Soon Kim ◽  
Je-Young Shin ◽  
Jung-Joon Sung
Keyword(s):  
Creatine Kinase ◽  
South Korea ◽  
Clinical Features ◽  
Serum Creatine Kinase ◽  
Guillain Barre Syndrome ◽  
Teaching Hospitals ◽  
Fisher Syndrome ◽  
Guillain Barré Syndrome ◽  
Male Sex ◽  
Guillain Barré

The aim of the present study was to investigate the frequency and clinical features of Guillain-Barré syndrome (GBS) with hyperCKemia. We retrospectively identified 139 patients with GBS at 2 teaching hospitals in South Korea. We excluded patients with Miller-Fisher syndrome (n = 19), acute bulbar palsy (n = 3), and those whose serum creatine kinase (CK) levels were not measured (n = 45). Twelve of 72 patients (16.7%) had transient hyperCKemia, defined as serum CK ≥300 IU/L. The frequency of male sex and non-demyelinating electrodiagnostic features were higher in patients with hyperCKemia than those without. Transient hyperCKemia, occasionally seen in patients with GBS may be associated with the non-demyelinating subtype.

scholarly journals The clinical features and long-term prognosis of asymmetry childhood Guillain-Barré syndrome: a 5-year follow-up.

2020 ◽  
Author(s):  
Rui-Di Sun ◽  
jun Jiang
Keyword(s):  
Infectious Disease ◽  
Clinical Features ◽  
Guillain Barre Syndrome ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Guillain Barré Syndrome ◽  
Motor Nerves ◽  
Long Term Prognosis ◽  
Guillain Barré

Abstract Backgroud: The aim was to investigate clinical features and long-term prognosis of asymmetric childhood Guillain-Barré syndrome (GBS). Methods: In a retrospective cohort study, standardized data from all children with GBS seen at the Wuhan Children’s Hospital were collected regarding clinical presentation, auxiliary examinations and long-term outcome. We compared asymmetry GBS with symmetry GBS. Asymmetry GBS was defined by Medical Research Council (MRC) grade and motor nerves conduction in bilateral limbs. Recovery was defined as a return to normal life with a DSS of 0. Results: GBS was diagnosed in 72 children. 12（16.67%）were asymmetry GBS compared to 60 symmetry GBS . In asymmetry GBS, six children were transient asymmetry weakness and six children were persistent asymmetry weakness. Compared to symmetry weakness GBS, asymmetry weakness GBS had more preschool children (75% vs 25%, P=0.005), longer days on hospital(26.5(15-37) days vs 11(9-15) days, p =0.000), more mechanical ventilation(MV) (50% vs 8.33%, p=0.000), higher Disease severity score(DSS)at nadir of disease(4(3-5) vs 3(1-4), p=0.010), more axonal subtypes(50% vs 15%, p=0.013) and more complications(58.33% vs 8.33%, p=0.000). Eight children had sequelae and sixty-four children had recovery. Compared to recovery group, sequelae group had more axonal subtypes(62.5% vs 15.63%, p=0.002) and more persistent asymmetry weakness(62.5% vs 4.69%, p=0.000). In six persistent asymmetry GBS, 5(83.33%) had abnormal EEG (electroencephalogram) results, 3(50%) children had mild to marked pleocytosis in CSF and 5(83.33%) had sequelae. Conclusions: In conclusion, asymmetry GBS had two types, namely transient and persistent asymmetry weakness. Asymmetry GBS indicated a more complex condition during disease. Most of persistent asymmetry GBS had clinical or subclinical infectious disease and poor prognosis. Inflammatory in anterior horn cells or nerve root by infectious disease may be the possible function in persistent asymmetry GBS.

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