The Arabidopsis leucine‐rich repeat receptor‐like kinase MIK2 is a crucial component of early immune responses to a fungal‐derived elicitor

AbstractPlant genomes encode hundreds of receptor kinases and peptides, but the number of known plant receptor-ligand pairs is limited. We report that the Arabidopsis leucine-rich repeat receptor kinase LRR-RK MALE DISCOVERER 1-INTERACTING RECEPTOR LIKE KINASE 2 (MIK2) is the receptor for the SERINE RICH ENDOGENOUS PEPTIDE (SCOOP) phytocytokines. MIK2 is necessary and sufficient for immune responses triggered by multiple SCOOP peptides, suggesting that MIK2 is the receptor for this divergent family of peptides. Accordingly, the SCOOP12 peptide directly binds MIK2 and triggers complex formation between MIK2 and the BRASSINOSTEROID INSENSITIVE 1-ASSOCIATED KINASE 1 (BAK1) co-receptor. MIK2 is required for resistance to the important root pathogen Fusarium oxysporum. Notably, we reveal that Fusarium proteomes encode SCOOP-like sequences, and corresponding synthetic peptides induce MIK2-dependent immune responses. These results suggest that MIK2 may recognise Fusarium-derived SCOOP-like sequences to induce immunity against Fusarium. The definition of SCOOPs as MIK2 ligands will help to unravel the multiple roles played by MIK2 during plant growth, development and stress responses.

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BAK1 Is Not a Target of the Pseudomonas syringae Effector AvrPto

Molecular Plant-Microbe Interactions ◽

10.1094/mpmi-04-10-0096 ◽

2011 ◽

Vol 24 (1) ◽

pp. 100-107 ◽

Cited By ~ 49

Author(s):

Tingting Xiang ◽

Na Zong ◽

Jie Zhang ◽

Jinfeng Chen ◽

Mingsheng Chen ◽

...

Keyword(s):

Cell Surface ◽

Immune Responses ◽

Pseudomonas Syringae ◽

Plant Cell ◽

Crucial Role ◽

Pathogenic Bacteria ◽

Effector Proteins ◽

Receptor Like Kinase ◽

Receptor Kinases ◽

New Evidence

Plant cell surface-localized receptor kinases such as FLS2, EFR, and CERK1 play a crucial role in detecting invading pathogenic bacteria. Upon stimulation by bacterium-derived ligands, FLS2 and EFR interact with BAK1, a receptor-like kinase, to activate immune responses. A number of Pseudomonas syringae effector proteins are known to block immune responses mediated by these receptors. Previous reports suggested that both FLS2 and BAK1 could be targeted by the P. syringae effector AvrPto to inhibit plant defenses. Here, we provide new evidence further supporting that FLS2 but not BAK1 is targeted by AvrPto in plants. The AvrPto-FLS2 interaction prevented the phosphorylation of BIK1, a downstream component of the FLS2 pathway.

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Isolation of a novel leucine-rich repeat receptor-like kinase (OsLRR2) gene from rice and analysis of its relation to abiotic stress responses

Biotechnology & Biotechnological Equipment ◽

10.1080/13102818.2016.1242377 ◽

2016 ◽

Vol 31 (1) ◽

pp. 51-57 ◽

Cited By ~ 5

Author(s):

Yongrong Liao ◽

Changqiong Hu ◽

Xuewei Zhang ◽

Xufeng Cao ◽

Zhengjun Xu ◽

...

Keyword(s):

Abiotic Stress ◽

Stress Responses ◽

Leucine Rich Repeat ◽

Receptor Like Kinase

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A Novel Aminosaccharide Compound Blocks Immune Responses by Toll-like Receptors and Nucleotide-binding Domain, Leucine-rich Repeat Proteins

Journal of Biological Chemistry ◽

10.1074/jbc.m110.108001 ◽

2010 ◽

Vol 286 (7) ◽

pp. 5727-5735 ◽

Cited By ~ 8

Author(s):

Kyoung-Hee Lee ◽

Yuen-Joyce Liu ◽

Amlan Biswas ◽

Chikako Ogawa ◽

Koichi S. Kobayashi

Keyword(s):

Immune Responses ◽

Nucleotide Binding ◽

Binding Domain ◽

Leucine Rich Repeat ◽

Toll Like Receptors ◽

Nucleotide Binding Domain ◽

Repeat Proteins

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Overexpression of the peanut CLAVATA1-like leucine-rich repeat receptor-like kinase AhRLK1 confers increased resistance to bacterial wilt in tobacco

Journal of Experimental Botany ◽

10.1093/jxb/erz274 ◽

2019 ◽

Vol 70 (19) ◽

pp. 5407-5421

Author(s):

Chong Zhang ◽

Hua Chen ◽

Rui-Rong Zhuang ◽

Yu-Ting Chen ◽

Ye Deng ◽

...

Keyword(s):

Bacterial Wilt ◽

Ralstonia Solanacearum ◽

Defense Response ◽

R Gene ◽

Leucine Rich Repeat ◽

Receptor Like Kinase ◽

Defense Response Signaling ◽

Resistance To Ralstonia Solanacearum

Overexpression of a novel peanut CLAVATA1-like gene significantly enhanced the resistance to Ralstonia solanacearum in tobacco via defense response signaling associated with EDS1-mediated R-gene pathways.

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