scholarly journals Organoleptic assessment and median lethal dose determination of oral aldicarb in rats

2020 ◽  
Vol 1480 (1) ◽  
pp. 136-145
Author(s):  
Nathaniel C. Rice ◽  
Noah A. Rauscher ◽  
Mark C. Moffett ◽  
Todd M. Myers
Keyword(s):  
Lethal Dose ◽  
Median Lethal Dose ◽  
Dose Determination

Development of a hydrogen cyanide inhalation exposure system and determination of the inhaled median lethal dose in the swine model

2018 ◽  
Vol 30 (4-5) ◽  
pp. 195-202 ◽  
Author(s):  
Jillian M. Staugler ◽  
Michael C. Babin ◽  
M. Claire Matthews ◽  
Matthew K. Brittain ◽  
Mark R. Perry
Keyword(s):  
Hydrogen Cyanide ◽  
Lethal Dose ◽  
Inhalation Exposure ◽  
Swine Model ◽  
Exposure System ◽  
Median Lethal Dose

scholarly journals Determination of median lethal dose of combination of endosulfan and cypermethrin in wistar rat

2013 ◽  
Vol 20 (1) ◽  
pp. 1 ◽  
Author(s):  
Anupuma Raina ◽  
Mohineesh Chandra ◽  
TirathD Dogra ◽  
Jaya Raj ◽  
Monika Pahuja
Keyword(s):  
Lethal Dose ◽  
Wistar Rat ◽  
Median Lethal Dose

scholarly journals Calculation of the Median Lethal Dose and Low Lethal Dose Using the CombiStats Biometric Software

2021 ◽  
Vol 11 (2) ◽  
pp. 135-142
Author(s):  
P. V. Shadrin ◽  
T. A. Batuashvili ◽  
L. V. Simutenko ◽  
N. P. Neugodova
Keyword(s):  
Specific Activity ◽  
Maximum Dose ◽  
Lethal Dose ◽  
Probit Analysis ◽  
Median Lethal Dose ◽  
Dose Determination ◽  
Activity Assessment ◽  
Calculation Results ◽  
The Russian Federation ◽  
Step Algorithm

The median lethal dose (LD50) and low lethal dose (LD10) are calculated in acute toxicity studies, as well as during specific activity assessment of some medicines. The aim of the study was to develop a procedure for using CombiStats to calculate LD50 and LD10. The authors proposed a step-by-step algorithm for processing bioassay results using the CombiStats biometric software (median effective dose determination model, probit analysis) with conversion of doses to simple fractions (fractions of the maximum dose) to calculate LD50 and LD10. They compared LD50 and LD10 calculation results obtained using CombiStats with those obtained using electronic spreadsheets according to the Bliss–Miller–Tainter–Prozorovsky method described in the State Pharmacopoeia of the Russian Federation (General Monograph 1.1.0014.15). It has been demonstrated that the use of CombiStats sometimes has advantages over the use of the pharmacoepoeial method.

Determination of the Median Lethal Dose of Botulinum Serotype E in Channel Catfish Fingerlings

2012 ◽  
Vol 24 (2) ◽  
pp. 105-109 ◽  
Author(s):  
Kamalakar Chatla ◽  
Patricia S. Gaunt ◽  
Larry Hanson ◽  
Dana X. Gao ◽  
Robert Wills
Keyword(s):  
Channel Catfish ◽  
Lethal Dose ◽  
Median Lethal Dose
Sign in / Sign up

Export Citation Format

Share Document