On the Applicability of Camera Lens Protectors in Emergency Luminescence Dosimetry

In this work, the optically stimulated luminescence (OSL) properties of camera lens protectors and their potential use in emergency dosimetry were investigated. Camera lens protectors can be attached to mobile phones, which are commonly carried by individuals and may be useful in estimating an emergency dose. The presented results confirm the great potential of this type of glass material for dose determination. The glass protectors exhibit advantageous properties, such as linear dose dependence in the range of at least 0.6–10 Gy, minimum detectable dose at the level of tens of mGy, and good measurement repeatability for samples of the same type. Significant fading during the first day after exposure is an undesirable feature of tested glass. Nevertheless, the application of the correction for fading shows promising results in the dose recovery process.

Pharmacological Effects of Lycopene- A Review

Carotenoids are pigments that are lipophilic in nature. Lycopene is an important dietary carotenoid that has been seen to be effective in managing and treating various medical conditions. It has aliphatic properties. It can be isolated from watermelons, tomatoes, and papayas. All the studies were examined separately according to need, like, dose determination, comparison with other similar products, their concentration in body fluid and also their effectiveness at different sites and types of comorbidities. It can prevent inflammatory and oxidative properties. Lycopene has pharmacological effects in diseases related to the central nervous system like Epilepsy, Alzheimer’s disease, Parkinson’s disease along with this it also exhibits Cardioprotective and anti-microbial properties. It is also noteworthy to mention that antioxidants help in protecting and preventing the condition of atherosclerosis.

Development of Standard X-Ray Beams for Calibration of Radiobiology Cabinet and Conformal Irradiators

This work seeks to develop standard X-ray beams that are matched to radiobiology X-ray irradiators. The calibration of detectors used for dose determination of these irradiators is performed with a set of standard X rays that are more heavily filtered and/or lower energy, which leads to a higher uncertainty in the dose measurement. Models of the XRad320, SARRP, and the X-ray tube at the University of Wisconsin Medical Radiation Research Center (UWMRRC) were created using the BEAMnrc user code of the EGSnrc Monte Carlo code system. These models were validated against measurements, and the resultant modeled spectra were used to determine the amount of added filtration needed to match the X-ray beams at the UWMRRC to those of the XRad320 and SARRP. The depth profiles and half-value layer (HVL) simulations performed using BEAMnrc agreed to measurements within 3% and 3.6%, respectively. A primary measurement device, a free-air chamber, was developed to measure air kerma in the medium energy range of X rays. The resultant spectra of the matched beams had HVL's that matched the HVL's of the radiobiology irradiators well within the 3% criteria recommended by the International Atomic Energy Agency (IAEA) and the average energies agreed within 2.4%. In conclusion, three standard X-ray beams were developed at the UWMRRC with spectra that more closely match the spectra of the XRad320 and SARRP radiobiology irradiators, which will aid in a more accurate dose determination during calibration of these irradiators.

Dissolution behaviour and imageability of ternary borate glasses for use in geniculate artery embolization

Sixteen borate glass compositions comprising K2O and SrO were screened, using a design of mixtures approach, to model compositional effects on dissolution, CT imageability, and MRI relaxivity (R2). Based on the characteristics of each network, together with dose determination and toxicological risk, the composition identified as BKSA16 was selected as a preferred composition for pre-clinical evaluations related to geniculate artery embolization (GAE). Accordingly, BKSA16 particles were subjected to a flame spheroidization process and recharacterized, including the evaluation of residual mass at 72 h in physiologically representative media along with clinical determinations of suspension time (ease of use). For both the irregular particles and microspheres residual mass was present at 72 h in physiologically representative media. Additionally, both the microspheres and irregular particles achieved suspension times deemed to be acceptable for clinical use. The collective data confirms that BKSA16 microspheres have a range of beneficial features (specifically both degradable and imageable) suited to GAE.

Dose Calculation and Measurement from B¹⁰(n, α)Li⁷ Reaction Using Filtered Neutron Beam at Nuclear Research Institute

In this research, dose calculation and measurement from B10 (n, α) Li7 reaction usingfiltered neutron beam at the Nuclear Research Institute have been reported. Calculation was carried out by Monte Carlo method using MCNP5 code. Neutron activation technique using vanadium foil was employed to determine neutron flux at various positions in phantom from which neutron dose has been calculated using conversion factor. These calculations are basics for the dose determination research of the Boron Neutron Capture Therapy (BNCT) in Vietnam.

Calculation of the Median Lethal Dose and Low Lethal Dose Using the CombiStats Biometric Software

The median lethal dose (LD50) and low lethal dose (LD10) are calculated in acute toxicity studies, as well as during specific activity assessment of some medicines. The aim of the study was to develop a procedure for using CombiStats to calculate LD50 and LD10. The authors proposed a step-by-step algorithm for processing bioassay results using the CombiStats biometric software (median effective dose determination model, probit analysis) with conversion of doses to simple fractions (fractions of the maximum dose) to calculate LD50 and LD10. They compared LD50 and LD10 calculation results obtained using CombiStats with those obtained using electronic spreadsheets according to the Bliss–Miller–Tainter–Prozorovsky method described in the State Pharmacopoeia of the Russian Federation (General Monograph 1.1.0014.15). It has been demonstrated that the use of CombiStats sometimes has advantages over the use of the pharmacoepoeial method.

Results of a study of optimal dose determination in wheat

In radiobiology, biological effects appear when a biological organism absorbs radiation energy over a critical value. Therefore, the absorption dose, defined as the energy absorbed per unit mass, is the only major parameter that used for characterizing radiation effect. A typical dose-response curve is the survival rate experiences a progress of slowly dropping-slightly ascending- rapidly decreasing. This phenomenon of survival –dose response is universal in ion implantation of plants. The percentage of root and first leaf length and damage effect of ion beam increased in the highest doses. Darkhan-181 variety was more radio-sensitivity than Darkhan-144 variety. The indices of LD50 determined in Darkhan-144 variety 125Gy and in Darkhan-181 150Gy doses. Both two varieties similar result sown in RD50 indices sown in 125Gy (Darkhan-144 48.7%, Darkhan-181 49.1%) dose. We are determined 125-150Gy dose of ion beam radiation is an optimal dose for those varieties. Буудайн сортод ионы туяаны тохиромжтой тун тогтоох судалгааны дүн Монгол орны газар тариаланд буудайн үйлдвэрлэл 80 гаруй хувийг эзлэх бөгөөд уг таримлын гадаад орчны нөхцөлд тэсвэртэй арвин ургацтай сортуудын хэрэгцээ шаардлага нэмэгдсээр байна. Шинэ сорт бүтээх селекцийн ажилд цөмийн энергийг ашиглан мутаци хувьслаар тухайн сортын дутагдалтай талыг сайжруулах, урьд байгаагүй шинж чанар бий болгох судалгааны ажил хийгдсээр байна. Цөмийн аль ч энергийг селекцийн зорилгоор ашиглаж байгаа үед тохиромжтой тунг олж тогтоох нь хамгийн чухал байдаг. Хэт өндөр тунгийн үйлчилэл ургамлын амьдралтад сөрөгөөр нөлөөлдөг бол хэт бага тунгийн үйлчилэлд мутаци үүсэх магадлал буурдаг байна. Дархан-181, Дархан-144 сортуудын хуурай үрийг ионы цацрагийн 25Gy, 50Gy, 75Gy, 100Gy, 125Gy, 150Gy, 175Gy, 200Gy, 225Gy, 250Gy, 275Gy тунгуудаар үйлчилэн тохиромжтой тунг тогтоохыг оролдсон юм. Лабораторийн соёололт, анхны навч болон үндэсний уртыг хэмжиж, аль тунгийн үйлчлэлд хамгийн их ба бага бууралт үзүүлсэнийг тогтоох замаар радиацийн мэдрэмжийг тодорхойлсон юм. Судлагдсан бүх сортууд тун ихсэхэд соёололт, навчны болон үндэсний урт буурсан ба хамгийн өндөр буюу 275Gy тунгаар үйлчлэхэд соёололт 95-97 % -иар буурсан байна. Түлхүүр үг: мутаци, радиацийн мэдрэмж, үйлчилгээ, анхны навчны урт, үндэсний уртын бууралт