scholarly journals The African swine fever virus isolate Belgium 2018/1 shows high virulence in European wild boar

2020 ◽  
Vol 67 (4) ◽  
pp. 1654-1659 ◽  
Author(s):  
Jutta Pikalo ◽  
Marie‐Eve Schoder ◽  
Julia Sehl ◽  
Angele Breithaupt ◽  
Maryléne Tignon ◽  
...  
2015 ◽  
Vol 160 (7) ◽  
pp. 1657-1667 ◽  
Author(s):  
Jana Pietschmann ◽  
Claire Guinat ◽  
Martin Beer ◽  
Valery Pronin ◽  
Kerstin Tauscher ◽  
...  

Author(s):  
Reet Herm ◽  
Heli Kirik ◽  
Annika Vilem ◽  
Laura Zani ◽  
Jan Hendrik Forth ◽  
...  

Pathogens ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 757
Author(s):  
Sandra Barroso-Arévalo ◽  
Jose A. Barasona ◽  
Estefanía Cadenas-Fernández ◽  
José M. Sánchez-Vizcaíno

African swine fever virus (ASFv) is one of the most challenging pathogens to affect both domestic and wild pigs. The disease has now spread to Europe and Asia, causing great damage to the pig industry. Although no commercial vaccine with which to control the disease is, as yet, available, some potential vaccine candidates have shown good results in terms of protection. However, little is known about the host immune mechanisms underlying that protection, especially in wild boar, which is the main reservoir of the disease in Europe. Here, we study the role played by two cytokines (IL-10 and IFN-γ) in wild boar orally inoculated with the attenuated vaccine candidate Lv17/WB/Rie1 and challenged with a virulent ASFv genotype II isolate. A group of naïve wild boar challenged with the latter isolate was also established as a control group. Our results showed that both cytokines play a key role in protecting the host against the challenge virus. While high levels of IL-10 in serum may trigger an immune system malfunctioning in challenged animals, the provision of stable levels of this cytokine over time may help to control the disease. This, together with high and timely induction of IFN-γ by the vaccine candidate, could help protect animals from fatal outcomes. Further studies should be conducted in order to support these preliminary results and confirm the role of these two cytokines as potential markers of the evolution of ASFV infection.


2020 ◽  
Vol 9 (32) ◽  
Author(s):  
S. Ndlovu ◽  
A.-L. Williamson ◽  
L. Heath ◽  
O. Carulei

ABSTRACT We report here the genome sequences of three African swine fever virus isolates obtained from a domestic pig (Zaire [Zaire]), a warthog (RSA/W1/1999 [South Africa]), and a European wild boar (RSA/2/2004 [South Africa]) belonging to genotypes IV, XX, and XX, respectively. This report increases the number of genotype XX, wild boar, and warthog reference sequences available.


2020 ◽  
Vol 10 (6) ◽  
pp. 2846-2859 ◽  
Author(s):  
Kim M. Pepin ◽  
Andrew J. Golnar ◽  
Zaid Abdo ◽  
Tomasz Podgórski

2016 ◽  
Vol 62 (5) ◽  
pp. 386-391 ◽  
Author(s):  
M. Frączyk ◽  
G. Woźniakowski ◽  
A. Kowalczyk ◽  
K. Niemczuk ◽  
Z. Pejsak

Virology ◽  
2013 ◽  
Vol 443 (1) ◽  
pp. 99-105 ◽  
Author(s):  
Charles C. Abrams ◽  
Lynnette Goatley ◽  
Emma Fishbourne ◽  
David Chapman ◽  
Lyndsay Cooke ◽  
...  

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