Magnetic resonance imaging patterns of tumor regression in breast cancer patients after neo-adjuvant chemotherapy, and an analysis of the influencing factors

2017 ◽  
Vol 23 (6) ◽  
pp. 656-662 ◽  
Author(s):  
ManMan Li ◽  
Bin Xu ◽  
Yingbo Shao ◽  
Hui Liu ◽  
BingJie Du ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Magnetic Resonance Imaging ◽  
Adjuvant Chemotherapy ◽  
Magnetic Resonance ◽  
Cancer Patients ◽  
Influencing Factors ◽  
Tumor Regression ◽  
Breast Cancer Patients ◽  
Resonance Imaging ◽  
Neo Adjuvant Chemotherapy

Yield of Selective Magnetic Resonance Imaging in Preoperative Workup of Newly Diagnosed Breast Cancer Patients Planned for Breast Conserving Surgery

2012 ◽  
Vol 78 (4) ◽  
pp. 451-455
Author(s):  
Tehillah S. Menes ◽  
Sivan Zissman ◽  
Orit Golan ◽  
Fani Sperber ◽  
Joseph Klausner ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Cancer Patients ◽  
Medical Center ◽  
Breast Conserving Surgery ◽  
Newly Diagnosed ◽  
Breast Cancer Patients ◽  
Resonance Imaging ◽  
Tel Aviv

The role of routine preoperative magnetic resonance imaging (MRI) in newly diagnosed breast cancer patients planned for breast conserving surgery is presently being debated. In our medical center we practice selective use of preoperative MRI; we sought to examine the yield of MRI in this highly selected group of patients. A retrospective study of all newly diagnosed breast cancer patients presenting between January 2007 and July 2010 to the Tel Aviv Sourasky Medical Center (Tel Aviv, Israel) was completed. Patients planned for breast conserving surgery who underwent preoperative MRI were included in this study. Patients and tumor characteristics, indication for MRI, findings on MRI, consequent workup, and impact on surgical treatment were recorded. Association between preoperative characteristics and yield of MRI was examined. During the study period, 105 patients that were candidates for breast conserving surgery underwent pre-operative evaluation with MRI. Use of breast MRI increased over time. Rates of mastectomy were stable throughout the study years. Dense mammogram was the most frequent (51, 68%) indication for MRI. Additional suspicious findings were found in 41 (39%) patients, prompting further workup including 36 biopsies in 25 patients, of which 22 (61%) were with cancer. These additional findings prompted a change in the surgical plan in a third of the patients. In most patients (92; 88%) clear margins were achieved. Limiting the use of MRI in the preoperative workup of breast cancer patients to a selected group of patients can increase the yield of MRI.

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