scholarly journals Does ABO blood group influence antibody response to SARS‐CoV ‐2 vaccination?

Vox Sanguinis ◽  
2021 ◽  
Author(s):  
Costanza Vicentini ◽  
Valerio Bordino ◽  
Alessandro Roberto Cornio ◽  
Davide Meddis ◽  
Savina Ditommaso ◽  
...  
Keyword(s):  
Antibody Response ◽  
Blood Group ◽  
Abo Blood Group ◽  
Group Influence

scholarly journals Longitudinal SARS-CoV-2 Seroconversion Course and Antibody Levels by Blood Groups in Convalescent Plasma Donors in Turkey

2021 ◽  
Author(s):  
Aziz Karaca ◽  
Mustafa Nuri Günçıkan ◽  
Nazlı Nadire Sözmen ◽  
Gizem Gökçe Karadağ ◽  
Mustafa Yılmaz
Keyword(s):  
Antibody Response ◽  
Blood Group ◽  
Antibody Level ◽  
Time Course ◽  
Blood Groups ◽  
Group Method ◽  
Abo Blood Group ◽  
Abo Blood Groups ◽  
Igg Antibody ◽  
Rh Blood Group

Objective: The present study investigates the seroconversion time course of the IgG antibody against SARS-CoV-2 and ascertains whether its levels change according to the patient’s ABO blood group. Method: A total of 36,003-convalescent plasma (CP) donations of 12,315 Turkish Red Crescent CP donors were analyzed. The ABO blood group of the CP donors was determined by Gel Centrifugation; and IgG was measured using the Euroimmun anti-SARS-CoV-2 ELISA. The differences in the distributions of mean IgG ratios among the different ABO blood groups were analyzed with One-Way ANOVA and Independent Samples T-test. Results: Among the CP donors, 98.4% were male. An antibody response to SARS-CoV-2 was noted-although in a few CP donors- on the 244th day, and a significant association between the ABO blood groups and the mean IgG ratios was noted (p: 0.001). The highest (mean±SD) antibody level was observed in the AB blood group (39.5±15.7), followed by the B (37.9±11.5) and the A blood groups (36.6±10.7), while the lowest value was recorded in the O blood group (34.4±11.5). Significant differences between all paired groups were noted in pairwise comparisons. The Rh (-) blood group (37.4±13.6) had a significantly higher antibody level than the Rh (+) blood group (36.3±11.2) (p: 0.005). Conclusion: An antibody response to SARS-CoV-2 was noted in a CP donor on the 244th day. The average IgG ratios were higher in the CP donors with the AB blood group, but lower in the O blood group. These results may be considered a valuable indication of the effectiveness of CP therapy used for the treatment of COVID-19 patients with clinically relevant blood types.

scholarly journals ABO blood group and SARS‐CoV‐2 antibody response in a convalescent donor population

Vox Sanguinis ◽  
2021 ◽  
Author(s):  
Evan M. Bloch ◽  
Eshan U. Patel ◽  
Christi Marshall ◽  
Kirsten Littlefield ◽  
Ruchika Goel ◽  
...  
Keyword(s):  
Antibody Response ◽  
Blood Group ◽  
Abo Blood Group ◽  
Donor Population

scholarly journals ABO blood group type does not influence the level of SARS-CoV-2 antibody response in convalescent plasma donors

2021 ◽  
Author(s):  
Klemen Žiberna ◽  
Katerina Jazbec ◽  
Mojca Jež ◽  
Polonca Mali ◽  
Urška Rahne Potokar ◽  
...  
Keyword(s):  
Antibody Response ◽  
Blood Group ◽  
Neutralizing Antibody ◽  
Antibody Test ◽  
Abo Blood Group ◽  
Serological Tests ◽  
Course Of Disease ◽  
Group Type ◽  
Group A ◽  
Blood Group Type

The association of ABO blood group types with the COVID-19 disease has been confirmed by several studies, with the blood group A-type patients being more susceptible and prone to more severe clinical course of disease. Similarly, some authors explored the association of ABO-types and the levels of anti-SARS-CoV-2 antibodies in convalescents. The recent reports mostly support a theory that non-O blood group convalescents present with higher levels of anti-SARS-CoV-2 antibodies. Since these findings were based on small convalescent cohorts, we quantified the anti-SARS-CoV-2 antibodiy levels in four larger cohorts of total 3185 convalescent plasma donors with three commercial serological tests and one standard neutralizing antibody test. The majority of donors had undergone a mild form of disease and the median time of sampling was 66 days after the onset of COVID-19 symptoms. None of the antibody quantitation methods showed an association of the ABO blood group types with the level of anti-SARS-CoV-2 antibodies. The same result is evident in the group of vaccinated individuals (n=370) as well as in the groups stratified into three post-COVID-19 periods (0-60, 60-120, and 120-180 days). In conclusion we can state that the ABO blood group type does not influence the level of SARS-CoV-2 antibody response in COVID-19 convalescent plasma donors.

scholarly journals DOES ABO BLOOD GROUP INFLUENCE RISK OR SEVERITY OF COVID-19?

2021 ◽  
Vol 77 (18) ◽  
pp. 3086
Author(s):  
Jeffrey L. Anderson ◽  
Heidi May ◽  
Stacey Knight ◽  
Tami Bair ◽  
Viet Le ◽  
...  
Keyword(s):  
Blood Group ◽  
Abo Blood Group ◽  
Group Influence

The Correlation Between ABO Blood Group and Neonatal Disease Severity

PEDIATRICS ◽  
2016 ◽  
Vol 137 (Supplement 3) ◽  
pp. 461A-461A
Author(s):  
Kacie E. McMahon ◽  
Jonathan K. Muraskas
Keyword(s):  
Disease Severity ◽  
Blood Group ◽  
Abo Blood Group ◽  
Neonatal Disease

A Caution in Association of ABO Blood Group with COVID-19

2020 ◽  
Keyword(s):  
Gene Cluster ◽  
Clinical Outcomes ◽  
Blood Group ◽  
Association Analysis ◽  
Blood Type ◽  
Genome Wide Association ◽  
Chromosome 3 ◽  
Abo Blood Group ◽  
Genome Wide Association Analysis ◽  
Genome Wide

A comment on Zhao J, Yang Y, Huang H, Li D, Gu D, Lu X, et al. Association of ABO blood group and Covid19 susceptability. medRxiv [PREPRINT]. 2020; https://doi.org/10.1101/2020.03.11.20031096. Zeng X, Fan H, Lu D, Huang F, Meng X, Li Z, et al. Association between ABO blood group and clinical outcomes of Covid19. medRxiv[PREPRINT].2020; https://doi.org/10.1101/2020.04.15.20063107. Zietz M, Tatonetti N. Testing the association between blood type and COVID-19 infection, intubation, and death medRxiv [PREPRINT]. 2020; https://doi.org/10.1101/2020.04.08.20058073. Ellinghaus D, Degenhardt F, Bujanda L, al. e. The ABO blood group and a chromosome 3 gene cluster associate with SRAS-CoV2 respitarory failure in an Italy-Spain genome-wide association analysis. medRxiv. 2020; https://doi.org/10.1101/2020.05.31.20114991.

scholarly journals ABO blood group and COVID‐19: a review on behalf of the ISBT COVID‐19 working group

Vox Sanguinis ◽  
2021 ◽  
Author(s):  
Ruchika Goel ◽  
Evan M. Bloch ◽  
France Pirenne ◽  
Arwa Z. Al‐Riyami ◽  
Elizabeth Crowe ◽  
...  
Keyword(s):  
Blood Group ◽  
Working Group ◽  
Abo Blood Group
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