L‐DOPA and 5‐HTP modulation of air‐stepping in newborn rats

2021 ◽  
Vol 599 (19) ◽  
pp. 4455-4476
Author(s):  
Marie Boulain ◽  
Wei Yuan ◽  
Zied Oueghlani ◽  
Inès Khsime ◽  
Vianney Salvi ◽  
...  
Keyword(s):  
Newborn Rats

Application of stereological analysis of cell volume to isolated myocytes in culture with and without adrenergic innervation

1990 ◽  
Vol 48 (3) ◽  
pp. 416-417
Author(s):  
Jane K. Rosenthal ◽  
Dianne L. Atkins ◽  
William J. Marvin ◽  
Penny A. Krumm
Keyword(s):  
Cardiac Myocytes ◽  
Structural Changes ◽  
Three Dimensional ◽  
Adrenergic Innervation ◽  
Culture Cell ◽  
Serial Sections ◽  
Newborn Rats ◽  
Primary Culture Cell ◽  
Biological Studies ◽  
Cell Volumes

To comprehend structural changes in cardiac myocytes accompanying adrenergic innervation, it is essential that a three dimensional analysis be performed. To date, biological studies which utilize stereological methods have been limited to cells in tissue and in organs. Our laboratory has utilized current stereological techniques for measuring absolute volumes of individual myocytes in primary culture. Cell volumes are calculated for two distinct groups of cells at 96 hours in culture: isolated myocytes and myocytes innervated with adrenergic neurons (Figure 1).Cardiac myocytes are cultured from the ventricular apices of newborn rats. Cells are plated directly onto tissue culture dishes with or without preplated explants from the paravertebral thoracolumbar sympathetic chain. On day four cultures are photographed and marked for one-to-one cell location. Following conventional fixation and embeddment in eponate-12, the cells are relocated and mounted for microtomy. The cells are completely sectioned at 120nm in their parallel orientation to the surface of the dish (Figure 2). Serial sections are collected on formvar coated slotted grids and are recorded in sequence.

Effect of prenatal glucocorticoids and postnatal nitric oxide inhalation on survival of newborn rats with nitroten-induced congenital diaphragmatic hernia

2001 ◽  
Vol 120 (5) ◽  
pp. A210-A210
Author(s):  
O MANN ◽  
C HUPPERTZ ◽  
C BLOECHLE ◽  
J IZBICKI ◽  
W LAMBRECHT ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Congenital Diaphragmatic Hernia ◽  
Diaphragmatic Hernia ◽  
Newborn Rats ◽  
Nitric Oxide Inhalation

Neurodegeneration in newborn rats following general anesthesia

2006 ◽  
Vol 37 (06) ◽  
Author(s):  
P Bittigau ◽  
S Bercker ◽  
T Kerner ◽  
B Bert ◽  
H Fink ◽  
...  
Keyword(s):  
General Anesthesia ◽  
Newborn Rats

HEMMUNG VON TESTOSTERONABHÄNGIGEN DIFFERENZIERUNGSVORGÄNGEN DER MÄNNLICHEN RATTE NACH DER GEBURT

1967 ◽  
Vol 54 (2) ◽  
pp. 227-240 ◽  
Author(s):  
F. Neumann ◽  
J. D. Hahn ◽  
M. Kramer
Keyword(s):  
Sexual Behaviour ◽  
Cyproterone Acetate ◽  
Post Partum ◽  
Sexual Attitude ◽  
Normal Male ◽  
Corpora Lutea ◽  
List Type ◽  
Newborn Rats ◽  
Neonatal Treatment ◽  
Triangular Shape

ABSTRACT Male newborn rats were injected with 2 mg of an antiandrogen (1,2α-methylene-6-chloro-pregna-4,6-dien-17α-ol-3,20-dione-17α-acetate = cyproterone acetate) daily from their 1st to their 14th day of life. The following effects of this treatment were observed in these animals after onset of sexual maturity: 84% of the animals are unable to reproduce. Penis: the frenulum is broadened to a lamina of triangular shape, which almost completely prevents the preputium from being pushed back. These males show a rather insufficient male sexual behaviour towards females in oestrus. After castration and ovar implantation, some of the treated animals show true corpora lutea and at attempts of cohabitation partially female sexual behaviour towards normal male animals. From these results it can be concluded, that differentiation of the penis is not completed at the time of birth. The infertility of the animals may be caused by the penile changes (difficulties with intromission) as well as by the aimless sexual behaviour. This aimless sexual behaviour, the ability to produce true corpora lutea and finally their partially female sexual attitude under the influence of the hormones from the implanted ovaries led to the conclusion, that the above described neonatal treatment apparently inhibited testosterone-depending post partum developments of sexual differentiation in hypothalamic centers.

Effect of prenatal isoxsuprine on pulmonary oxygen toxicity in the newborn rat

1980 ◽  
Vol 48 (3) ◽  
pp. 505-510 ◽  
Author(s):  
L. Frank ◽  
J. Summerville ◽  
D. Massaro
Keyword(s):  
Enzyme Activities ◽  
Oxygen Toxicity ◽  
Fetal Lung ◽  
Antioxidant Enzyme Activities ◽  
Newborn Rats ◽  
Lung Maturation ◽  
Lung Weight ◽  
Pregnant Rats ◽  
Rat Pups ◽  
Hyperoxic Exposure

Isoxsuprine, a beta-sympathomimetic agent used clinically to delay premature parturition and to possibly accelerate fetal lung maturation, was administered to pregnant rats at 48 and 24 h prior to delivery. Newborn rats were placed in 96-98% O2 (or room air) to determine if the prenatal isoxsuprine treatment compromised their tolerance to prolonged hyperoxic exposure. (Exogenous catecholamines are known to exacerbate O2 toxicity in adult animals). Survival of the isoxsuprine-treated pups in O2 (52%) was no different than for control neonates exposed to hyperoxia for 7 days (57%) (P = 0.22). Body weight, lung weight, lung protein, and DNA content of the newborns were also not altered by the prenatal isoxsuprine treatment. Lung antioxidant enzyme activities for superoxide dismutase, catalase, and glutathione peroxidase were the same at birth in the isoxsuprine-treated and control rat pups, and the enzyme activities increased in response to hyperoxic exposure in each group to an equivalent degree. Thus, in utero treatment with isoxsuprine had no apparent adverse effect on newborn rats exposed to a prolonged O2 challenge.

Neuroprotective effect of astaxanthin on newborn rats exposed to prenatal maternal seizures

2019 ◽  
Vol 148 ◽  
pp. 63-69 ◽  
Author(s):  
Yan Lu ◽  
Xiuxia Wang ◽  
Jiaojiao Feng ◽  
Tao Xie ◽  
Peipei Si ◽  
...  
Keyword(s):  
Neuroprotective Effect ◽  
Newborn Rats

Cadmium exposure in newborn rats ovary induces developmental disorders of primordial follicles and the differential expression of SCF/c-kit gene

2017 ◽  
Vol 280 ◽  
pp. 20-28 ◽  
Author(s):  
Wenchang Zhang ◽  
Tingting Wu ◽  
Chenyun Zhang ◽  
Lingfeng Luo ◽  
Meimei Xie ◽  
...  
Keyword(s):  
Differential Expression ◽  
Developmental Disorders ◽  
Cadmium Exposure ◽  
Newborn Rats ◽  
Primordial Follicles ◽  
Kit Gene

scholarly journals Comparative catalytic properties of liver glycogen synthases from adult and newborn rats.

1980 ◽  
Vol 255 (4) ◽  
pp. 1351-1357
Author(s):  
D.M. Haverstick ◽  
A.H. Gold
Keyword(s):  
Catalytic Properties ◽  
Liver Glycogen ◽  
Newborn Rats
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