scholarly journals Identificación de cadáveres sometidos a altas temperaturas, a partir de las características macroscópicas de sus órganos dentales y la aplicabilidad de la genética forense / Identification of Bodies Exposed to High Temperatures Based on Macroscopic...

2016 ◽  
Vol 35 (74) ◽  
Author(s):  
María Del Socorro Barraza Salcedo ◽  
Martha Leonor Rebolledo Cobos
Keyword(s):  
High Temperatures ◽  
Dental Pulp ◽  
Literature Search ◽  
Forensic Genetics ◽  
Forensic Odontology ◽  
Genetic Identification ◽  
Dental Tissues ◽  
Relationship Of ◽  
The Relationship ◽  
Forensic Genetic

<p><strong>ABSTRACT. </strong><em><strong>Background:</strong></em> Forensic dentistry in cases of incineration provides scientific elements that allow the identification of bodies, by analyzing dental organs, through the isolation of DNA obtained from the pulp as an alternative to confirm the identity of the victim. When the degree of temperature is highly elevated, dental tissues are vulnerable and therefore the DNA pulp is not salvageable, wasting resources and time by lack of standards to identify macroscopic characteristics that indicate this situation reliably. <em><strong>Objective:</strong></em> To describe the main features of teeth subjected to high temperatures and the relationship of these to the viability of their DNA, as a contribution to forensic genetic identification. <em><strong>Methods:</strong></em> A literature search for three databases were used; Pubmed, EBSCO and Google academician, 50 articles were selected in several languages, which made regarding the descriptors "cremated teeth; violence; Forensic Odontology; ID; DNA samples; dental pulp". <em><strong>Results:</strong></em> Most authors reported the resistance of dental tissues when subjected to high temperatures and others showed the success of the identification through dental comparisons. <em><strong>Conclusions:</strong></em> A successful identification evidenced by DNA extracted from bone and dental remains. The literature reviewed suggests that up to certain temperatures, can be carried out identification by forensic genetics of cremated victims by DNA contained in dental pulp. Strict national referencing was observed in the physical characteristics or incinerated dental macroscopic bodies.</p>

scholarly journals Obesity = inflammation. Pathogenesis. How does this threaten men?

2020 ◽  
Vol 11 (4) ◽  
pp. 6-23
Author(s):  
Z. Sh. Pavlova ◽  
I. I. Golodnikov
Keyword(s):  
Adipose Tissue ◽  
Literature Search ◽  
Web Of Science ◽  
The Body ◽  
Energy Resources ◽  
Intrinsic Properties ◽  
Endocrine Organ ◽  
Relationship Of ◽  
The Relationship ◽  
Pro Inflammatory Cytokines

Today, adipose tissue has ceased to be perceived only as an energetic substance with its intrinsic properties in the form of thermoregulation and mechanical protection, known since the beginning of the twentieth century. Today, adipose tissue is a fullfledged endocrine organ that is distributed throughout the body — the usefulness of its work directly affects the energy balance, not only through involvement in the metabolism of carbohydrates and fats, but also by the production of many adipokines, a total of more than 600 known today. This review research the causal relationship of subclinical or systemic inflammation of adipose tissue with an excess of energy resources, insulin resistance, leptin, adiponectin, estrogen metabolites and one of the most pro-inflammatory cytokines - interleukin 6. Attention is also paid to the relationship between prostate cancer and obesity, as an ambiguous relationship due to the maximum paying attention to testosterone. Further study of adipose tissue will make it possible to establish specific pathophysiological mechanisms responsible for the development of not only disorders of carbohydrate metabolism, but also a number of other systems in view of the not fully understood systemic action of adipokines and associated inflammatory mediators in obese individuals. Systematic literature search was perform in the Medline, Scopus, Web of Science and elibrary databases.

scholarly journals GENETIC IDENTIFICATION AS THE CRITERION OF PRIMARY ERRORS BEHIND THE REGISTRATION OF CATTLE ON THE TERRITORY OF THE URALS FEDERAL DISTRICT

2020 ◽  
Author(s):  
Я.А. КАБИЦКАЯ ◽  
Л.А. КАЛАШНИКОВА ◽  
Е.Г. БОЙКО ◽  
А.Е. КАЛАШНИКОВ
Keyword(s):  
Nuclear Dna ◽  
Genetic Relationships ◽  
Molecular Genetic ◽  
Quality Standard ◽  
Mendelian Inheritance ◽  
Genetic Identification ◽  
Meat Production ◽  
Technical Data ◽  
Relationship Of ◽  
The Relationship

Для организации селекционно-племенной работы необходимо уточнение данных о родстве потомков крупного рогатого скота молочного и мясного направлений продуктивности при помощи молекулярно-генетических методов. Для осуществления этой задачи производилось сравнение данных первичного учета о родстве животных из информационно-аналитической системы (ИАС) СЕЛЭКС с менделевским наследованием генотипов от родителей потомкам, определенных при помощи ДНК тестирования. В качестве определения родства использовался простой и доступный метод анализа микросателлитных локусов ядерной ДНК. Для выполнения исследований создан и систематизирован банк образцов ДНК животных (крупный рогатый скот молочного и мясного направлений продуктивности) в количестве 4716 голов. Показана степень ошибочных записей в родословной потомков по данным первичного учета и результатов генотипирования на адаптированной панели 15 микросателлитных участков ядерного генома животных предприятий Тюменской и Курганской областей, а также ХМАО-Югра. Из 531 «троек» (мать-потомок-отец) животных молочного направления продуктивности выявлено не менее 88% совпадений по обоим родителям. По родителям для черно-пестрой породы выявлено до 3% ошибочных записей в родословной потомков, для голштинской – до 11%. Для мясных пород животных величина ошибок по генетической идентификации для абердин-ангус составила до 10% и герефорд – до 25%. Установлено, что микросателлиты являются инструментом для определения достоверности происхождения по международному стандарту и проверки данных первичной регистрации зоотехнических данных и генетической идентификации крупного рогатого скота молочного и мясного направлений продуктивности. It is necessary to clarify data on the relationship of cattle progeny in the directions of dairy and meat production by molecular genetic methods and organization of breeding work. To accomplish this task, a comparison of primary registration data on the relationship of animals from the information-analytical system (IAS) was carried out taking into computation the Mendelian inheritance of genotypes from parents to offspring identifi ed using DNA testing. A simple and affordable method for analyzing micro-satellite nuclear DNA loci was used as a defi nition of genetic relationships. A genetic bank of cattle samples was created and systematized for 4716 animals for research purposes. The extent of incorrect entries in the pedigree of descendants is given according to the primary counting data and the results of genotyping in the panel of 15 micro-satellite loci for animal enterprises of the Tyumen and Kurgan regions, as well as the Khanty-Mansi Autonomous Okrug-Yugra was observed. At least 88% of the matches were found for both parents of 531 “triples“ (mother-offspringfather) animals of the milk cattle. Up to 3% of incorrect entries in the pedigree of offspring for the black-motley breed and up to 11% for Holstein were identifi ed for their parents. The genetic identifi cation errors for meat breeds for Aberdeen Angus was achieved in 10% and Hereford to 25%. It is established that micro-satellites are a tool for determining the accuracy of origin, according to the worldwide quality standard. They are suitable for verifying primary zoo-technical data and genetic identifi cation of dairy and beef cattle.

Bioinformatics Study on Relationship of Inflammation and Phospholipids Based on Cytoscape Software

2013 ◽  
Vol 791-793 ◽  
pp. 1656-1659
Author(s):  
Zhong Feng Shi ◽  
Yi Fan Feng ◽  
Wen Rui ◽  
Yan Mei Zhong
Keyword(s):  
Literature Search ◽  
Bioinformatics Study ◽  
Relationship Of ◽  
The Relationship

Phospholipids are one of important factors in inflammation development. To discover relationship of inflammation and phospholipids, we carried out the bioinformatics study on relationship of inflammation and phospholipids by Cytoscape software with Agilent Literature Search and ClusterONE plugins loaded. We found 7 predominant network pathway which could explain the relationship of inflammation and phospholipids. The Cytoscape software with Agilent Literature Search and ClusterONE plugins is very powerful tool for discover potential pathways to explain Pathophysiology mechanism.

The relationship of the scleractinian corals to the rugose corals

Paleobiology ◽  
1980 ◽  
Vol 6 (02) ◽  
pp. 146-160 ◽  
Author(s):  
William A. Oliver
Keyword(s):  
Critical Points ◽  
Scleractinian Corals ◽  
Convincing Evidence ◽  
Early Triassic ◽  
Rugose Corals ◽  
History Of ◽  
The Subject ◽  
Relationship Of ◽  
The Relationship ◽  
Biologic Factors

The Mesozoic-Cenozoic coral Order Scleractinia has been suggested to have originated or evolved (1) by direct descent from the Paleozoic Order Rugosa or (2) by the development of a skeleton in members of one of the anemone groups that probably have existed throughout Phanerozoic time. In spite of much work on the subject, advocates of the direct descent hypothesis have failed to find convincing evidence of this relationship. Critical points are:(1) Rugosan septal insertion is serial; Scleractinian insertion is cyclic; no intermediate stages have been demonstrated. Apparent intermediates are Scleractinia having bilateral cyclic insertion or teratological Rugosa.(2) There is convincing evidence that the skeletons of many Rugosa were calcitic and none are known to be or to have been aragonitic. In contrast, the skeletons of all living Scleractinia are aragonitic and there is evidence that fossil Scleractinia were aragonitic also. The mineralogic difference is almost certainly due to intrinsic biologic factors.(3) No early Triassic corals of either group are known. This fact is not compelling (by itself) but is important in connection with points 1 and 2, because, given direct descent, both changes took place during this only stage in the history of the two groups in which there are no known corals.

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