scholarly journals Obesity = inflammation. Pathogenesis. How does this threaten men?

2020 ◽  
Vol 11 (4) ◽  
pp. 6-23
Author(s):  
Z. Sh. Pavlova ◽  
I. I. Golodnikov

Today, adipose tissue has ceased to be perceived only as an energetic substance with its intrinsic properties in the form of thermoregulation and mechanical protection, known since the beginning of the twentieth century. Today, adipose tissue is a fullfledged endocrine organ that is distributed throughout the body — the usefulness of its work directly affects the energy balance, not only through involvement in the metabolism of carbohydrates and fats, but also by the production of many adipokines, a total of more than 600 known today. This review research the causal relationship of subclinical or systemic inflammation of adipose tissue with an excess of energy resources, insulin resistance, leptin, adiponectin, estrogen metabolites and one of the most pro-inflammatory cytokines - interleukin 6. Attention is also paid to the relationship between prostate cancer and obesity, as an ambiguous relationship due to the maximum paying attention to testosterone. Further study of adipose tissue will make it possible to establish specific pathophysiological mechanisms responsible for the development of not only disorders of carbohydrate metabolism, but also a number of other systems in view of the not fully understood systemic action of adipokines and associated inflammatory mediators in obese individuals. Systematic literature search was perform in the Medline, Scopus, Web of Science and elibrary databases.

2021 ◽  
Vol 18 (3) ◽  
pp. 320-326
Author(s):  
V. A. Beloglazov ◽  
I. A. Yatskov ◽  
E. D. Kumelsky ◽  
V. V. Polovinkina

This review article presents data from the literature, which provide an idea of the relationship between metabolic disorders occurring against the background of obesity and endotoxinemia, as well as the effect of these conditions on the maintenance of low-grade inflammation in the body. A description of the hormonal and immune restructuring of white adipose tissue, the main routes of entry and metabolism of endotoxin is given. Particular attention is paid to the mechanisms of the mutual influence of obesity and endotoxinemia. Described by Yakovlev M.Yu. in 1988 «endotoxin aggression» and Cani P.D. et al. in 2007, «metabolic endotoxinemia», in our opinion, is one of the most important triggers for the development and progression of a whole spectrum of acute and chronic diseases. Based on the data of recent years, adipose tissue is an active endocrine organ capable of influencing both metabolic processes and the state of innate and acquired immune defense mechanisms. It has now been proven that high-calorie diets lead not only to an increase in overweight, but also to an increase in the level of endotoxin circulating in the blood. An in-depth study of the ability of obesity and endotoxinemia to potentiate the mutual pro-inflammatory effect can help both in understanding the pathogenesis of the main cardiovascular, autoimmune, allergic and infectious (including viral) diseases, and in the development of methods for non-pharmacological and drug correction of these conditions.


Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 1812-P
Author(s):  
MARIA D. HURTADO ◽  
J.D. ADAMS ◽  
MARCELLO C. LAURENTI ◽  
CHIARA DALLA MAN ◽  
CLAUDIO COBELLI ◽  
...  

2017 ◽  
Vol 59 (2) ◽  
pp. 014-021
Author(s):  
Saya K. Koyshibaeva ◽  
◽  
Shokhan A. Alpeyisov ◽  
Evgeniy V. Fedorov ◽  
Nina S. Badryzlova ◽  
...  

Author(s):  
Joshua S. Walden

The book’s epilogue explores the place of musical portraiture in the context of posthumous depictions of the deceased, and in relation to the so-called posthuman condition, which describes contemporary changes in the relationship of the individual with such aspects of life as technology and the body. It first examines Alfred Hitchcock’s Vertigo to view how Bernard Herrmann’s score relates to issues of portraiture and the depiction of the identity of the deceased. It then considers the work of cyborg composer-artist Neil Harbisson, who has aimed, through the use of new capabilities of hybridity between the body and technology, to convey something akin to visual likeness in his series of Sound Portraits. The epilogue shows how an examination of contemporary views of posthumous and posthuman identities helps to illuminate the ways music represents the self throughout the genre of musical portraiture.


PMLA ◽  
1932 ◽  
Vol 47 (1) ◽  
pp. 89-96
Author(s):  
Daniel C. Boughner

From Plato and Aristotle, Hippocrates and Galen, through the medieval commentators, the Elizabethans inherited a body of complex psychological principles. An examination of these principles and their bearing on The Faerie Queene has so far been only casual and incidental. Since in Book ii, Canto ix, the poet combines one of the most widely used of medieval motifs—the conception of the body as a world, city, or castle—with certain current doctrines of psychology, such an inquiry is especially apposite. Spenser's use of the abundant contemporaneous literature of psychology affords material for an extended treatment such as that which Miss Anderson has made of Shakespeare's plays. The present study purposes to set forth one aspect of his system of psychology—his psychology of memory in the allegory of the Castle of Alma, to make clear the relationship of his system to the current Elizabethan doctrines, and to establish the purpose of certain departures from those doctrines.


Author(s):  
Martin Eisner

This article investigates the significance of the manuscripts of Virgil and other classical poets that Dante might have read. Calling attention to the presence of musical notation (neumes) in copies that share the particular Virgilian readings Dante quotes, this essay explores the resonance of one of those passages (Aeneas’ dream of Hector) in Dante’s poem. It shows how Dante uses this Virgilian episode to craft his encounter with Manfred where he considers the relationship of body and soul that constitutes one of the major differences between classical and Christian thought, as Augustine frequently noted. Just as Christian anthropology maintains that the body constitutes an essential element of the human person, this essay argues that the materiality of the texts Dante read constitutes a crucial source for understanding how Dante interpreted these texts.


1964 ◽  
Vol 6 (2) ◽  
pp. 169-178 ◽  
Author(s):  
R. V. Large

1. Thirty Suffolk × Half bred lambs were slaughtered at the following ages: two twin lambs at birth and two singles and two twins at 1, 2, 3, 4, 6, 8 and 16 weeks of age.2. The following weights were recorded: live-weight immediately before slaughter; and carcass, head, skin, feet, alimentary tract, heart, liver, kidneys, lungs and trachea, and blood immediately afterwards.3. The alimentary tract was emptied and weighed in four separate parts; reticulo-rumen, omasum-abomasum, small intestine, large intestine.4. The volumes of the reticulo-rumen and the omasum-abomasum were measured by immersing in water and filling the organs with water to 2 cm. pressure.5. The in vitro digestive efficiency of rumen liquor from lambs of 1, 2, 3 and 4 weeks of age was assessed.6. Empty body weight was considered to be valuable in comparing animals of different ages or from different feeding regimes or at different times of the year because variations in gut ‘fill’ were eliminated.7. There were no differences between singles and twins in the relationship of the fresh weights of the parts of the body to empty body weight, except that development of the liver and the blood was rather slower for singles.8. Little evidence was found of a difference in rate of development of the alimentary tract between singles an d twins, although the log an d square root transformation suggested a possible difference in reticulo-rumen size in favour of twins, significant at the 5% level.


Author(s):  
Luis Raul Meza Mendoza ◽  
María Elena Moya Martinez ◽  
Angelica Maria Sabando Suarez

Since the beginning of humanity, an attempt has been made to explain the way in which man acquires knowledge, the way in which he assimilates, processes and executes it in order to develop the teaching-learning process that people need throughout of his life, which forces to change the learning schemes using new study methodologies, such as neuroscience, which is a discipline that studies the functioning of the brain, the relationship of neurons to the formation of synapses creating immediate responses which transmits to the body voluntarily and involuntarily, in addition to controlling the central and peripheral nervous system with their respective functions. It is necessary to change the traditional scheme and implement new strategies that allow the teacher to venture into neuroscience, in order to individually understand the different learning processes that students do. As some authors of neuroscience say, the brain performs processes of acquisition, storage and evocation of information, which form new knowledge schemes that generate changes in the attitude of the human being, for this reason teachers are responsible for taking advantage of what It is known about the multiple functions of the brain and be clear about the various ways of acquiring knowledge.


2020 ◽  
Vol 80 (316) ◽  
pp. 441
Author(s):  
Welder Lancieri Marchini ◽  
Renan Silva Carletti

O presente artigo discute a noçao de corpo a partir do filósofo contemporâneo Byung-Chul Han e como ela pode oferecer caminhos para pensar a constituição do sujeito na atualidade. Partiremos da exposição dos conceitos de positividade e negatividade descritos em A Sociedade do Cansaco e em outras obras do autor. Em seguida, abordaremos a relação do corpo com a liberdade e pornografia. Por último, mostraremos como a inserção e o reconhecimento do sujeito em suas relações sociais pode sugerir um caminho possível para ultrapassar o excesso de positividade característico de nossa época. Abstract: This article discusses the notion of body from the contemporary philosopher Byung-Chul Han and how it can offer ways to think about the subject’s constitution today. We will start from the exposition of the concepts of positivity and negativity described in The Burnout Socieity and other works by the author. Next, we will address the relationship of the body to freedom and pornography. Finally, we will show how the subject’s insertion and recognition in his social relations can suggest a possible way to overcome the excess of positivity characteristic of our time.Keywords: Freedom; Pornography; Subject; Transparency.


2019 ◽  
Vol 4 (2) ◽  
pp. 114-129
Author(s):  
Hamam Burhanuddin

The study in this paper are explain about the studies of medical (medicine) blood type have the same relationship to human character because the blood producing antibodies and antigens. It could determine a person helpless hold strong or weak body, has an allergy to something or not, in the blood also contains various nutrients (like protein) and also the oxygen being supplied to the brain and nerves and body affect performance someone will then be emanated from the attitude of the person and social interaction. As has been explained, but keep in mind, there is blood in the genes, the nature of which is carried in the body/genotif rightly so it is, but we can not ignore the fenotif/nature arising or visible, this trait appear due to interaction between genes and the environment, so even if the person is smart in the intelligentsia and emotional, but grew up in a bad environment is going to be a bad trait. The theory of personality based on blood type can be used as a reference in parenting children through an understanding of the fundamental principles of the application of personality accompanied by parenting. Furthermore, the taking of steps in the care tailored to the stage of development of the child, in the Qur'an explicitly did not mentioned paragraph that discusses about blood type, but in the Qur'an there are blood (ad-Dam), Islamic studies in the study of Children is seen as a mandate from God, forming 3-dimensional relationships, with parents as the central figure. First, her parents relationship with God that is backed by the presence of children. Second, the relationship of the child (which still need a lot of guidance) with God through his parents. Third, the relationship of the child with both parents under the tutelage and guidance of God.


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