Design and Particle Image Velocimetry Investigation of a Turbulent Mini-Jet Hemolysis Testing Apparatus

Author(s):  
Thomas W. R. Fountain ◽  
Steven W. Day

Hemolysis is the break up of red blood cells, and is a condition that is of concern during the design process of blood contacting prostheses. In turbulent flows, hemolysis has been most often correlated to Reynolds shear stress. Mini-scale turbulent jets have been used for hemolysis experiments because they allow for explicit control of shear. Quantitative predictions of hemolysis from shear stress are unreliable, with experimentally determined threshold Reynolds stresses for turbulent shear flow range from 400Pa to 5000Pa, with recent experiments at 800Pa. Reynolds stresses are a statistic of large scale turbulence, and act at spatial scales much larger than that of a red blood cell. It has been suggested in literature that hemolysis may be related to stresses induced by turbulent energy dissipation, which acts as a spatial scale closer to that of a red blood cell. The dissipation of turbulence kinetic energy occurs at the Kolmogorov scales, which is generally similar in scale to that of a red blood cell.

2021 ◽  
Vol 2099 (1) ◽  
pp. 012033
Author(s):  
G V Zasko ◽  
P A Perezhogin ◽  
A V Glazunov ◽  
E V Mortikov ◽  
Y M Nechepurenko

Abstract Large-scale inclined organized structures in stably stratified turbulent shear flows were revealed in the numerical simulation and indirectly confirmed by the field measurements in the stable atmospheric boundary layer. Spatial scales and forms of these structures coincide with those of the optimal disturbances of a simplified linear model. In this paper, we clarify the relation between the organized structures and the optimal disturbances, analyzing a time series of turbulent fields obtained by the RANS model with eddy viscosity/diffusivity and stochastic forcing generating the small-scale turbulence.


2007 ◽  
Vol 570 ◽  
pp. 307-346 ◽  
Author(s):  
P. J. A. PRIYADARSHANA ◽  
J. C. KLEWICKI ◽  
S. TREAT ◽  
J. F. FOSS

The mean wall-normal gradients of the Reynolds shear stress and the turbulent kinetic energy have direct connections to the transport mechanisms of turbulent-boundary-layer flow. According to the Stokes–Helmholtz decomposition, these gradients can be expressed in terms of velocity–vorticity products. Physical experiments were conducted to explore the statistical properties of some of the relevant velocity–vorticity products. The high-Reynolds-number data (Rθ≃O(106), where θ is the momentum thickness) were acquired in the near neutrally stable atmospheric-surface-layer flow over a salt playa under both smooth- and rough-wall conditions. The low-Rθdata were from a database acquired in a large-scale laboratory facility at 1000 >Rθ> 5000. Corresponding to a companion study of the Reynolds stresses (Priyadarshana & Klewicki,Phys. Fluids, vol. 16, 2004, p. 4586), comparisons of low- and high-Rθas well as smooth- and rough-wall boundary-layer results were made at the approximate wall-normal locationsyp/2 and 2yp, whereypis the wall-normal location of the peak of the Reynolds shear stress, at each Reynolds number. In this paper, the properties of thevωz,wωyanduωzproducts are analysed through their statistics and cospectra over a three-decade variation in Reynolds number. Hereu,vandware the fluctuating streamwise, wall-normal and spanwise velocity components and ωyand ωzare the fluctuating wall-normal and spanwise vorticity components. It is observed thatv–ωzstatistics and spectral behaviours exhibit considerable sensitivity to Reynolds number as well as to wall roughness. More broadly, the correlations between thevand ω fields are seen to arise from a ‘scale selection’ near the peak in the associated vorticity spectra and, in some cases, near the peak in the associated velocity spectra as well.


Author(s):  
Hinori Ito ◽  
Tatsuya Tsuneyoshi ◽  
Shan Feng ◽  
Takahiro Ito ◽  
Yoshiyuki Tsuji ◽  
...  

We simultaneously measured the flow field and wall shear stress in a straight pipe and behind an orifice by means of particle image velocimetry (PIV) and the limiting diffusion current technique (LDCT), respectively[1]. The spatio-temporal correlation coefficients of the local vertical velocity and the shear stress fluctuations are presented, and the canonical correlations between the proper orthogonal decomposition (POD) spatial eigenmodes in the recirculation region and the wall shear stress are also discussed[2]. A response time lag occurs between the wall shear stress and the velocity field. The large canonical correlation between the POD eigenmodes and wall shear stress suggests that large-scale flow structures are important for the shear stress fluctuation. These analyses are applied to the shear flow in channel and large scale motions are studied in relation with the shear stress fluctuations.


Soft Matter ◽  
2020 ◽  
Vol 16 (26) ◽  
pp. 6191-6205 ◽  
Author(s):  
Fabio Guglietta ◽  
Marek Behr ◽  
Luca Biferale ◽  
Giacomo Falcucci ◽  
Mauro Sbragaglia

Computational Fluid Dynamics is currently used to design and improve the hydraulic properties of biomedical devices, wherein the large scale blood circulation needs to be simulated by accounting for the mechanical response of RBCs at the mesoscale.


1996 ◽  
Vol 118 (4) ◽  
pp. 728-736 ◽  
Author(s):  
S. P. Mislevy ◽  
T. Wang

The effects of adverse pressure gradients on the thermal and momentum characteristics of a heated transitional boundary layer were investigated with free-stream turbulence ranging from 0.3 to 0.6 percent. Boundary layer measurements were conducted for two constant-K cases, K1 = −0.51 × 10−6 and K2 = −1.05 × 10−6. The fluctuation quantities, u′, ν′, t′, the Reynolds shear stress (uν), and the Reynolds heat fluxes (νt and ut) were measured. In general, u′/U∞, ν′/U∞, and νt have higher values across the boundary layer for the adverse pressure-gradient cases than they do for the baseline case (K = 0). The development of ν′ for the adverse pressure gradients was more actively involved than that of the baseline. In the early transition region, the Reynolds shear stress distribution for the K2 case showed a near-wall region of high-turbulent shear generated at Y+ = 7. At stations farther downstream, this near-wall shear reduced in magnitude, while a second region of high-turbulent shear developed at Y+ = 70. For the baseline case, however, the maximum turbulent shear in the transition region was generated at Y+ = 70, and no near-wall high-shear region was seen. Stronger adverse pressure gradients appear to produce more uniform and higher t′ in the near-wall region (Y+ < 20) in both transitional and turbulent boundary layers. The instantaneous velocity signals did not show any clear turbulent/nonturbulent demarcations in the transition region. Increasingly stronger adverse pressure gradients seemed to produce large non turbulent unsteadiness (or instability waves) at a similar magnitude as the turbulent fluctuations such that the production of turbulent spots was obscured. The turbulent spots could not be identified visually or through conventional conditional-sampling schemes. In addition, the streamwise evolution of eddy viscosity, turbulent thermal diffusivity, and Prt, are also presented.


2004 ◽  
Vol 126 (4) ◽  
pp. 613-619 ◽  
Author(s):  
David I. Graham

In this paper, an analytical solution is found for the Reynolds equations describing a simple turbulent shear flow carrying small, wake-less particles. An algebraic stress model is used as the basis of the model, the particles leading to source terms in the equations for the turbulent stresses in the flow. The sources are proportional to the mass loading of the particles and depend on the temporal correlations of the fluid velocities seen by particles, Rijτ. The resulting set of equations is a system of nonlinear algebraic equations for the Reynolds stresses and the dissipation. The system is solved exactly and the influence of the particles can be quantified. The predictions are compared with DNS results and are shown to predict trends quite well. Different scenarios are investigated, including the effects of isotropic, anisotropic and non-equilibrium time scales and negative loops in Rijτ. The general trend is to increase anisotropy and attenuate turbulence with higher mass loadings. The occurrence of turbulence enhancement is investigated and shown to be theoretically possible, but physically unlikely.


2001 ◽  
Vol 448 ◽  
pp. 53-80 ◽  
Author(s):  
Z. LIU ◽  
R. J. ADRIAN ◽  
T. J. HANRATTY

Turbulent flow in a rectangular channel is investigated to determine the scale and pattern of the eddies that contribute most to the total turbulent kinetic energy and the Reynolds shear stress. Instantaneous, two-dimensional particle image velocimeter measurements in the streamwise-wall-normal plane at Reynolds numbers Reh = 5378 and 29 935 are used to form two-point spatial correlation functions, from which the proper orthogonal modes are determined. Large-scale motions – having length scales of the order of the channel width and represented by a small set of low-order eigenmodes – contain a large fraction of the kinetic energy of the streamwise velocity component and a small fraction of the kinetic energy of the wall-normal velocities. Surprisingly, the set of large-scale modes that contains half of the total turbulent kinetic energy in the channel, also contains two-thirds to three-quarters of the total Reynolds shear stress in the outer region. Thus, it is the large-scale motions, rather than the main turbulent motions, that dominate turbulent transport in all parts of the channel except the buffer layer. Samples of the large-scale structures associated with the dominant eigenfunctions are found by projecting individual realizations onto the dominant modes. In the streamwise wall-normal plane their patterns often consist of an inclined region of second quadrant vectors separated from an upstream region of fourth quadrant vectors by a stagnation point/shear layer. The inclined Q4/shear layer/Q2 region of the largest motions extends beyond the centreline of the channel and lies under a region of fluid that rotates about the spanwise direction. This pattern is very similar to the signature of a hairpin vortex. Reynolds number similarity of the large structures is demonstrated, approximately, by comparing the two-dimensional correlation coefficients and the eigenvalues of the different modes at the two Reynolds numbers.


2016 ◽  
Vol 5 (2) ◽  
pp. 174-176 ◽  
Author(s):  
Delong Xie ◽  
Xiaolin Ren ◽  
Yuhui Xie ◽  
Xinya Zhang ◽  
Shijun Liao

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