Integrated Mixing/Reaction Micro Flow Cell for Chemical and Biochemical Applications

1999 ◽  
Author(s):  
Ryosuke Nakamura ◽  
Shuichi Shoji ◽  
Akira Yotsumoto

Abstract An integrated mixing/reaction micro flow cell which consists of a sample/reagent mixing channel, a visible port and a reaction chamber was designed, fabricated and tested. A micro cone hole array of macro porous Si was employed for reagent injection part. A visible light transparent PDMS slab was used as the visible port. A Ti-Pt thin film heater and a p-n junction diode temperature sensor were integrated on the reaction chamber to realize feedback temperature control. Uniform mixing and precise temperature control were realized by the fabricated micro flow cell. The striate and simple microchannel structure of the micro flow cell is suitable for multiplexed micro reactor for chemical and biochemical applications.

2017 ◽  
Vol 5 (1) ◽  
Author(s):  
Jun-gu Kang ◽  
Joon-Shik Park ◽  
Kwang-Bum Park ◽  
Junho Shin ◽  
Eung-An Lee ◽  
...  

2010 ◽  
Vol 93-94 ◽  
pp. 105-108 ◽  
Author(s):  
A. Lekwichai ◽  
S. Porntheeraphat ◽  
Win Bunjongpru ◽  
W. Sripumkhai ◽  
J. Supadech ◽  
...  

In this study, we demonstrate the disposable polydimethylsiloxane (PDMS) microchip provided for DNA amplification. The device consists of two main parts. The first part is PDMS/glass stationary chamber, the other part is a temperature-control microdevice on SiO2/Si substrate. This device consists of a thin film Pt-microheater and a Pt-temperature sensor, which were fabricated with CMOS compatible process. The performance of the device in the DNA amplification shows that, with 10 μl of PCR mixture volume, the approximately 700 bp DNA were successfully amplified within 50 minutes by 30 PCR cycles. The amplified products were comparable with those of a conventional method using electrophoresis. The PCR chip is also suitable for mass production.


2016 ◽  
Vol 23 (2) ◽  
pp. 455-463 ◽  
Author(s):  
Jan Kehres ◽  
Thomas Pedersen ◽  
Federico Masini ◽  
Jens Wenzel Andreasen ◽  
Martin Meedom Nielsen ◽  
...  

The design, fabrication and performance of a novel and highly sensitive micro-reactor device for performingin situgrazing-incidence X-ray scattering experiments of model catalyst systems is presented. The design of the reaction chamber, etched in silicon on insulator (SIO), permits grazing-incidence small-angle X-ray scattering (GISAXS) in transmission through 10 µm-thick entrance and exit windows by using micro-focused beams. An additional thinning of the Pyrex glass reactor lid allows simultaneous acquisition of the grazing-incidence wide-angle X-ray scattering (GIWAXS).In situexperiments at synchrotron facilities are performed utilizing the micro-reactor and a designed transportable gas feed and analysis system. The feasibility of simultaneousin situGISAXS/GIWAXS experiments in the novel micro-reactor flow cell was confirmed with CO oxidation over mass-selected Ru nanoparticles.


Author(s):  
L.N. Moskvin ◽  
О.V. Rodinkov ◽  
А.L. Moskvin ◽  
V. Spivakovskii ◽  
A.Y. Vlasov ◽  
...  

1994 ◽  
Author(s):  
Glenn Beheim ◽  
Jorge L. Sotomayor ◽  
Meg L. Tuma ◽  
Massood Tabib-Azar

2010 ◽  
Vol 29-32 ◽  
pp. 349-353
Author(s):  
Jing Tang ◽  
En Xing Zheng

The paper designs a temperature control system based on AT89C51 and DS18B20. The design uses the DS18B20 digital temperature sensor as the temperature acquisition unit and the AT89C51 microcontroller unit to control them, not only have the advantages that easy to control and with good flexibility, but also can greatly enhance the controlled temperature index.


2011 ◽  
Vol 80-81 ◽  
pp. 693-697
Author(s):  
Chang Hong Ji ◽  
Bin Zhen Zhang ◽  
Jian Zhang ◽  
Xiang Hong Li ◽  
Jian Lin Liu

In order to measure the pressure in the ultra-low temperature condition, the structure of ultra-low temperature piezoresistive pressure sensor is designed. Polysilicon nanometer thin film is used as a varistor according to its temperature and piezoresistive characteristics. The effect of the dimensions of silicon elastic membrane for the sensor sensitivity and the strain dimensions of the elastic membrane are analyzed, then layout position of resistances is arranged. The package structure of pressure sensor is designed. Meanwhile, a low-temperature sensor is designed to compensate the temperature influence to the pressure sensor.


2020 ◽  
Vol 10 (1) ◽  
pp. 31-37
Author(s):  
Mohammad Hasan Fuadi

Diesel engines is generally used for industrial and agricultural machines. Few people care about the engine temperature so it is forced to reach temperature of 100oC, which causes overheating of the diesel engine and has an impact on the performance itself. This also uses a hopper cooling system which is certainly not effective, because it's necessary to see that the water in the reservoir is still or not, also not equipped with an engine temperature display so it's difficult to ascertain the temperature inside. This study aims to monitor and control the temperature of cooling water. Operation of temperature control uses a telecontrol system that is connected to network (Internet of Things) so diesel temperature control can be done remotely. Monitoring of temperature and water level in the reserve tank using Web Mobile. In addition, there is a temperature sensor that is used to measure the temperature of the cooling water so that users can monitor the temperature of the diesel engine on Web Mobile. The test results obtained, the temperature sensor has an average temperature reading error of 0.031004%. Diesel engines with controlled solenoid valve cooling systems can produce ideal temperatures compared to when the solenoid valve is open (using the radiator continuously) or when the solenoid valve is Closed (without using a radiator). When the solenoid is controlled the engine temperature can be ideal because the solenoid valve opening and closing system has the lowest temperature of 56.34oC and the highest temperature of only 80.85oC.


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