Fluorescent proteins as singlet oxygen photosensitizers: mechanistic studies in photodynamic inactivation of bacteria

2013 ◽  
Author(s):  
Rubén Ruiz-González ◽  
John H. White ◽  
Aitziber L. Cortajarena ◽  
Montserrat Agut ◽  
Santi Nonell ◽  
...  
Keyword(s):  
Singlet Oxygen ◽  
Fluorescent Proteins ◽  
Photodynamic Inactivation ◽  
Mechanistic Studies ◽  
Inactivation Of Bacteria

scholarly journals The role of singlet oxygen and oxygen concentration in photodynamic inactivation of bacteria

2007 ◽  
Vol 104 (17) ◽  
pp. 7223-7228 ◽  
Author(s):  
T. Maisch ◽  
J. Baier ◽  
B. Franz ◽  
M. Maier ◽  
M. Landthaler ◽  
...  
Keyword(s):  
Singlet Oxygen ◽  
Oxygen Concentration ◽  
Photodynamic Inactivation ◽  
Inactivation Of Bacteria

A helpful technology - the luminescence detection of singlet oxygen to investigate photodynamic inactivation of bacteria (PDIB)

2010 ◽  
Vol 3 (5-6) ◽  
pp. 319-327 ◽  
Author(s):  
Johannes Regensburger ◽  
Tim Maisch ◽  
Ariane Felgenträger ◽  
Francesco Santarelli ◽  
Wolfgang Bäumler
Keyword(s):  
Singlet Oxygen ◽  
Photodynamic Inactivation ◽  
Luminescence Detection ◽  
Inactivation Of Bacteria

Surface plasmon-photosensitizer resonance coupling: an enhanced singlet oxygen production platform for broad-spectrum photodynamic inactivation of bacteria

2014 ◽  
Vol 2 (40) ◽  
pp. 7073-7081 ◽  
Author(s):  
Bo Hu ◽  
Xian Cao ◽  
Keaton Nahan ◽  
Joseph Caruso ◽  
Hong Tang ◽  
...  
Keyword(s):  
Singlet Oxygen ◽  
Surface Plasmon ◽  
Broad Spectrum ◽  
Photodynamic Inactivation ◽  
Oxygen Production ◽  
Production Platform ◽  
Resonance Coupling ◽  
Inactivation Of Bacteria

A general platform to improve singlet oxygen productionviaresonance coupling between surface plasmon and photosensitizers, and for broad-spectrum photodynamic inactivation of bacteria.

LED irradiation of halogen/nitrogen-doped polymeric graphene quantum dots triggers the photodynamic inactivation of bacteria in infected wounds

Carbon ◽  
2020 ◽  
Author(s):  
Hao-Hsin Huang ◽  
Anisha Anand ◽  
Chin-Jung Lin ◽  
Han-Jia Lin ◽  
Yang-Wei Lin ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Graphene Quantum Dots ◽  
Photodynamic Inactivation ◽  
Nitrogen Doped ◽  
Infected Wounds ◽  
Inactivation Of Bacteria ◽  
Led Irradiation

[18O]-Labeled Singlet Oxygen as a Tool for Mechanistic Studies of 8-Oxo-7,8-Dihydroguanine Oxidative Damage: Detection of Spiroiminodihydantoin, Imidazolone and Oxazolone Derivatives

2002 ◽  
Vol 383 (3-4) ◽  
Author(s):  
G.R. Martinez ◽  
M.H.G. Medeiros ◽  
J.-L. Ravanat ◽  
J. Cadet ◽  
P. Di Mascio
Keyword(s):  
Oxidative Damage ◽  
Damage Detection ◽  
Singlet Oxygen ◽  
Mechanistic Studies

Design of a Metallacycle‐Based Supramolecular Photosensitizer for In Vivo Image‐Guided Photodynamic Inactivation of Bacteria

2021 ◽  
Author(s):  
Yuling Xu ◽  
Wei Tuo ◽  
Liang Yang ◽  
Yan Sun ◽  
Chonglu Li ◽  
...  
Keyword(s):  
Photodynamic Inactivation ◽  
Image Guided ◽  
Inactivation Of Bacteria

On the Mechanism of the Acridine Orange Sensitized Photodynamic Inactivation of Lysozyme

1976 ◽  
Vol 31 (1-2) ◽  
pp. 29-39 ◽  
Author(s):  
Peter Rosenkranz ◽  
I. Basic Kinetics ◽  
Hartmut Schmidt
Keyword(s):  
Singlet Oxygen ◽  
Acridine Orange ◽  
Ph Value ◽  
Photodynamic Inactivation ◽  
Rate Process ◽  
First Order ◽  
Quenching Process ◽  
Pseudo First Order ◽  
Kinetics Of ◽  
Excited Oxygen

The kinetics of the photodynamic desactivation of lysozyme in presence of acridine orange as the sensitizer have been investigated in detail varying oxygen, protein, dye concentration, ionic strength and pH value. The kinetics can be approximately described as an over all pseudo-first- order rate process. Changing the solvent from water to D2O or by quenching experiments in pres­ence of azide ions it could be shown that the desactivation of lysozyme is caused exclusively by singlet oxygen. The excited oxygen occurs via the triplet state of the dye with a rate constant considerably lower than that to be expected for a diffusionally controlled reaction. Singlet oxygen reacts chemically (desactivation, k=2.9 × 107 ᴍ-1 sec-1) and physically (quenching process, k = 4.1 × 108 ᴍ-1sec-1) with the enzyme. The kinetical analysis shows that additional chemical reactions between singlet oxygen and lysozyme would have only little influence on the kinetics of the desactivation as long as their products would be enzymatically active and their kinetical constants would be less than about 1 × 108 ᴍ-1 sec-1.

Sign in / Sign up

Export Citation Format

Share Document