Can ImageNet feature maps be applied to small histopathological datasets for the classification of breast cancer metastatic tissue in whole slide images?

: Breast Cancer is a common dangerous disease for women. In the world, many women died due to Breast cancer. However, in the initial stage, the diagnosis of breast cancer can save women's life. To diagnose cancer in the breast tissues there are several techniques and methods. The image processing, machine learning and deep learning methods and techniques are presented in this paper to diagnose the breast cancer. This work will be helpful to adopt better choices and reliable methods to diagnose breast cancer in an initial stage to survive the women's life. To detect the breast masses, microcalcifications, malignant cells the different techniques are used in the Computer-Aided Diagnosis (CAD) systems phases like preprocessing, segmentation, feature extraction, and classification. We have been reported a detailed analysis of different techniques or methods with their usage and performance measurement. From the reported results, it is concluded that for the survival of women’s life it is essential to improve the methods or techniques to diagnose breast cancer at an initial stage by improving the results of the Computer-Aided Diagnosis systems. Furthermore, segmentation and classification phases are challenging for researchers for the diagnosis of breast cancer accurately. Therefore, more advanced tools and techniques are still essential for the accurate diagnosis and classification of breast cancer.

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A Study on Multi Class Classification from Breast Cancer Images using Ensemble Network and Transfer Learning

Recent Patents on Engineering ◽

10.2174/1872212114999201109205421 ◽

2020 ◽

Vol 14 ◽

Author(s):

Lahari Tipirneni ◽

Rizwan Patan

Keyword(s):

Breast Cancer ◽

Neural Network ◽

Convolutional Neural Network ◽

Binary Classification ◽

Disease Diagnosis ◽

Feature Descriptors ◽

Histopathological Images ◽

Viable Approach ◽

Multi Class Classification

Abstract:: Millions of deaths all over the world are caused by breast cancer every year. It has become the most common type of cancer in women. Early detection will help in better prognosis and increases the chance of survival. Automating the classification using Computer-Aided Diagnosis (CAD) systems can make the diagnosis less prone to errors. Multi class classification and Binary classification of breast cancer is a challenging problem. Convolutional neural network architectures extract specific feature descriptors from images, which cannot represent different types of breast cancer. This leads to false positives in classification, which is undesirable in disease diagnosis. The current paper presents an ensemble Convolutional neural network for multi class classification and Binary classification of breast cancer. The feature descriptors from each network are combined to produce the final classification. In this paper, histopathological images are taken from publicly available BreakHis dataset and classified between 8 classes. The proposed ensemble model can perform better when compared to the methods proposed in the literature. The results showed that the proposed model could be a viable approach for breast cancer classification.

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Hormonal characterization and classification of breast cyst fluid in gross cystic mastopathy

Endocrine Related Cancer ◽

10.1677/erc.0.0010049 ◽

1994 ◽

Vol 1 (2) ◽

pp. 49-55 ◽

Cited By ~ 2

Author(s):

I Számel ◽

B Budai ◽

K Daubner ◽

J Kralovánszky ◽

Sz Ottó ◽

...

Keyword(s):

Breast Cancer ◽

Sex Steroids ◽

Linear Regression Analysis ◽

Cyst Fluid ◽

Type I ◽

Breast Cyst Fluid ◽

Breast Cyst ◽

Apocrine Metaplasia ◽

Endocrine Parameters

ABSTRACT Gross cystic disease (GCD) of the breast may be associated with a higher risk for the development of breast cancer. High levels of sex steroids, steroid hormone precursors, prolactin and cations have been found in breast cyst fluid (BCF) by several investigators. Accordingly, endocrine parameters and the cationic composition of BCF may be considered as useful characteristics to follow patients bearing macrocysts. In this study we have investigated the concentrations of estradiol (E2), progesterone, testosterone, dehydroepiandrosterone (DHA) and DHA-3-sulfate (DHA-S), prolactin, potassium (K+) and sodium (Na+) in BCF aspirated from 99 women. The mean age of the patients was 49.8 years (range 32-58). The hormone levels were measured by RIA methods; K+ and Na+ were determined by flame photometry. Estradiol, progesterone, testosterone, DHA, DHA-S, prolactin and K+ showed significant accumulation in the BCF compared with their respective serum values. The K+/Na+ ratio proved to be useful in dividing cysts into type I (≥1), type II (<1 but ≥0.1) and type III (<0.1) subgroups. For type I BCF, higher DHA, DHA-S and prolactin concentrations were detected. Linear regression analysis established a highly significant (P<0.001) correlation between the concentrations of E2 and DHA-S (r=0.686), and also between testosterone and DHA-S (r=0.711). These findings indicate that type I BCF might be a marker for 'active' GCD of the breast, and suggest that it may be associated with an increased breast cancer risk, since this group of patients is supposed to have cysts with apocrine metaplasia. It is suggested therefore that when BCF is aspirated, sex steroids, steroid precursors and cations should be routinely measured, and women with type I cysts should be regularly examined.

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Differential Deep Convolutional Neural Network Model for Brain Tumor Classification

Brain Sciences ◽

10.3390/brainsci11030352 ◽

2021 ◽

Vol 11 (3) ◽

pp. 352

Author(s):

Isselmou Abd El Kader ◽

Guizhi Xu ◽

Zhang Shuai ◽

Sani Saminu ◽

Imran Javaid ◽

...

Keyword(s):

Neural Network ◽

Magnetic Resonance Imaging ◽

Brain Tumor ◽

Magnetic Resonance ◽

Brain Tumors ◽

Medical Image ◽

Resonance Imaging ◽

Feature Maps ◽

Deep Cnn

The classification of brain tumors is a difficult task in the field of medical image analysis. Improving algorithms and machine learning technology helps radiologists to easily diagnose the tumor without surgical intervention. In recent years, deep learning techniques have made excellent progress in the field of medical image processing and analysis. However, there are many difficulties in classifying brain tumors using magnetic resonance imaging; first, the difficulty of brain structure and the intertwining of tissues in it; and secondly, the difficulty of classifying brain tumors due to the high density nature of the brain. We propose a differential deep convolutional neural network model (differential deep-CNN) to classify different types of brain tumor, including abnormal and normal magnetic resonance (MR) images. Using differential operators in the differential deep-CNN architecture, we derived the additional differential feature maps in the original CNN feature maps. The derivation process led to an improvement in the performance of the proposed approach in accordance with the results of the evaluation parameters used. The advantage of the differential deep-CNN model is an analysis of a pixel directional pattern of images using contrast calculations and its high ability to classify a large database of images with high accuracy and without technical problems. Therefore, the proposed approach gives an excellent overall performance. To test and train the performance of this model, we used a dataset consisting of 25,000 brain magnetic resonance imaging (MRI) images, which includes abnormal and normal images. The experimental results showed that the proposed model achieved an accuracy of 99.25%. This study demonstrates that the proposed differential deep-CNN model can be used to facilitate the automatic classification of brain tumors.

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Classiﬁcation of Breast Cancer Histopathology Images by Cell-Centered Deep Learning Approach

2020 28th Signal Processing and Communications Applications Conference (SIU) ◽

10.1109/siu49456.2020.9302066 ◽

2020 ◽

Author(s):

Emre Egriboz ◽

Berkay Gokcen ◽

Gokhan Bilgin

Keyword(s):

Breast Cancer ◽

Deep Learning ◽

Learning Approach ◽

Histopathology Images

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