Classification of Breast Cancer Resistant Protein (BCRP) Inhibitors and Non-Inhibitors Using Machine Learning Approaches

2015 ◽  
Vol 18 (5) ◽  
pp. 476-485 ◽  
Author(s):  
Vilas Belekar ◽  
Karthik Lingineni ◽  
Prabha Garg
Keyword(s):  
Breast Cancer ◽  
Machine Learning ◽  
Learning Approaches ◽  
Breast Cancer Resistant Protein

Machine Learning-Aided Automatic Detection of Breast Cancer

2022 ◽  
pp. 274-290
Author(s):  
M. Abdul Jawad ◽  
Farida Khursheed
Keyword(s):  
Breast Cancer ◽  
Machine Learning ◽  
Computer Vision ◽  
Deep Learning ◽  
Early Stage ◽  
Survival Rates ◽  
Learning Approaches ◽  
Learning Techniques ◽  
Segmentation Image

The expeditious progress of machine learning, especially the deep learning techniques, keep propelling the medical imaging community's heed in applying these techniques in improving the accuracy of cancer screening. Among various types of cancers, breast cancer is the most detrimental disease affecting women today. The prognosis of such types of disease becomes a very challenging task for radiologists due the huge number of cases together with careful and thorough examination it demands. The constraints of present CAD open up a need for new and accurate detection procedures. Deep learning approaches have gained a tremendous recognition in the areas of object detection, segmentation, image recognition, and computer vision. Precise and premature detection and classification of lesions is very critical for increasing the survival rates of patients. Recent CNN models are designed to enhance radiologists' understandings to identify even the least possible lesions at the very early stage.

scholarly journals Classification of Oil Palm Female Inflorescences Anthesis Stages Using Machine Learning Approaches

2020 ◽  
Author(s):  
Mamehgol Yousefi ◽  
Azmin Shakrine ◽  
Samsuzana bt. Abd Aziz ◽  
Syaril Azrad ◽  
Mohamed Mazmira ◽  
...  
Keyword(s):  
Machine Learning ◽  
Oil Palm ◽  
Learning Approaches

scholarly journals A Review of Computer-Aided Expert Systems for Breast Cancer Diagnosis

Cancers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 2764
Author(s):  
Xin Yu Liew ◽  
Nazia Hameed ◽  
Jeremie Clos
Keyword(s):  
Breast Cancer ◽  
Machine Learning ◽  
Deep Learning ◽  
Main Process ◽  
Learning Approaches ◽  
Learning Methods ◽  
Advantages And Disadvantages ◽  
Computer Aided ◽  
Conventional Methods ◽  
The Impact

A computer-aided diagnosis (CAD) expert system is a powerful tool to efficiently assist a pathologist in achieving an early diagnosis of breast cancer. This process identifies the presence of cancer in breast tissue samples and the distinct type of cancer stages. In a standard CAD system, the main process involves image pre-processing, segmentation, feature extraction, feature selection, classification, and performance evaluation. In this review paper, we reviewed the existing state-of-the-art machine learning approaches applied at each stage involving conventional methods and deep learning methods, the comparisons within methods, and we provide technical details with advantages and disadvantages. The aims are to investigate the impact of CAD systems using histopathology images, investigate deep learning methods that outperform conventional methods, and provide a summary for future researchers to analyse and improve the existing techniques used. Lastly, we will discuss the research gaps of existing machine learning approaches for implementation and propose future direction guidelines for upcoming researchers.

scholarly journals Breast Cancer Type Classification Using Machine Learning

2021 ◽  
Vol 11 (2) ◽  
pp. 61
Author(s):  
Jiande Wu ◽  
Chindo Hicks
Keyword(s):  
Breast Cancer ◽  
Gene Expression ◽  
Machine Learning ◽  
Triple Negative Breast Cancer ◽  
Triple Negative ◽  
Genomic Research ◽  
Support Vector ◽  
Cancer Type ◽  
Classification Models

Background: Breast cancer is a heterogeneous disease defined by molecular types and subtypes. Advances in genomic research have enabled use of precision medicine in clinical management of breast cancer. A critical unmet medical need is distinguishing triple negative breast cancer, the most aggressive and lethal form of breast cancer, from non-triple negative breast cancer. Here we propose use of a machine learning (ML) approach for classification of triple negative breast cancer and non-triple negative breast cancer patients using gene expression data. Methods: We performed analysis of RNA-Sequence data from 110 triple negative and 992 non-triple negative breast cancer tumor samples from The Cancer Genome Atlas to select the features (genes) used in the development and validation of the classification models. We evaluated four different classification models including Support Vector Machines, K-nearest neighbor, Naïve Bayes and Decision tree using features selected at different threshold levels to train the models for classifying the two types of breast cancer. For performance evaluation and validation, the proposed methods were applied to independent gene expression datasets. Results: Among the four ML algorithms evaluated, the Support Vector Machine algorithm was able to classify breast cancer more accurately into triple negative and non-triple negative breast cancer and had less misclassification errors than the other three algorithms evaluated. Conclusions: The prediction results show that ML algorithms are efficient and can be used for classification of breast cancer into triple negative and non-triple negative breast cancer types.

scholarly journals Machine learning approaches to predict the Plant-associated phenotype of Xanthomonas strains

BMC Genomics ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Dennie te Molder ◽  
Wasin Poncheewin ◽  
Peter J. Schaap ◽  
Jasper J. Koehorst
Keyword(s):  
Machine Learning ◽  
Plant Pathogens ◽  
De Novo ◽  
Classification Algorithms ◽  
Learning Approaches ◽  
Enabling Factors ◽  
Essential Step ◽  
The World ◽  
Genome Content

Abstract Background The genus Xanthomonas has long been considered to consist predominantly of plant pathogens, but over the last decade there has been an increasing number of reports on non-pathogenic and endophytic members. As Xanthomonas species are prevalent pathogens on a wide variety of important crops around the world, there is a need to distinguish between these plant-associated phenotypes. To date a large number of Xanthomonas genomes have been sequenced, which enables the application of machine learning (ML) approaches on the genome content to predict this phenotype. Until now such approaches to the pathogenomics of Xanthomonas strains have been hampered by the fragmentation of information regarding pathogenicity of individual strains over many studies. Unification of this information into a single resource was therefore considered to be an essential step. Results Mining of 39 papers considering both plant-associated phenotypes, allowed for a phenotypic classification of 578 Xanthomonas strains. For 65 plant-pathogenic and 53 non-pathogenic strains the corresponding genomes were available and de novo annotated for the presence of Pfam protein domains used as features to train and compare three ML classification algorithms; CART, Lasso and Random Forest. Conclusion The literature resource in combination with recursive feature extraction used in the ML classification algorithms provided further insights into the virulence enabling factors, but also highlighted domains linked to traits not present in pathogenic strains.

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