Correlates and Determinants of Bone Mineral Density in Prepubertal Girls

2002 ◽  
Vol 14 (4) ◽  
pp. 345-357 ◽  
Author(s):  
Peter N. Wiebe ◽  
Cameron J.R. Blimkie ◽  
Nathalie Farpour-Lambert ◽  
Julie Briody ◽  
Helen Woodhead ◽  
...  

The correlates and determinants of total body (TB), femoral neck (FN), greater trochanter (GT) and leg areal bone mineral density (aBMD), and FN volumetric (vol) BMD were investigated in 42 healthy 6–10-year-old girls. Predictor variables included age, height, weight, lean tissue mass (LTM), fat mass, percent body fat, physical activity level, calcium intake, isokinetic knee flexion and extension strength and endocrine (E2) status. Bone density and body composition were determined by dual energy-x-ray absorptiometry (DEXA), and pubertal status was self-determined. LTM, weight, age, knee extensor strength and fat mass were significantly correlated (Pearson correlation coefficients; 0.36 £ r ‡ 0.62) with TBaBMD. These same variables with the addition of height and knee flexor strength were significantly correlated (0.33 £ r ‡ 0.77) with leg aBMD. Only LTM correlated significantly with FNaBMD and none of the independent variables correlated with FNvolBMD or GTaBMD. Only LTM entered as a significant predictor in multiple linear regression analysis (R2 = 46.7%) for TBaBMD. In conclusion, estradiol status, dietary calcium intake and physical activity level appeared not to be important predictors of BMD in this population, whereas LTM was consistently correlated with most BMD measures and was the single significant determinant of TBaBMD in this study.

Author(s):  
Glauber Dallanezi ◽  
Beatriz Freire ◽  
Eliana Nahás ◽  
Jorge Nahás-Neto ◽  
José Corrente ◽  
...  

2015 ◽  
Vol 3 (2) ◽  
pp. 23-32 ◽  
Author(s):  
Ali Monemi Amiri ◽  
Seyed Reza Hosseini ◽  
Farhad Rahmaninia ◽  
Hajighorban Nooreddini ◽  
Ali Bijani ◽  
...  

2017 ◽  
Vol 31 (4) ◽  
pp. 787-796
Author(s):  
Najoua Adriana Salomão ◽  
Amandio Aristides Rihan Geraldes ◽  
Adriano Eduardo Lima-Silva

The aim of this study was to verify the effect of physical activity level on bone mineral density (BMD) in pre-menopausal women with lactose intolerance. Sixty women was engaged in this study (age: 31.9±6.9 years) and were initially separated into two groups: 30 women with lactose intolerance (LI) and 30 controls (C). The groups were further subdivided into less and more active using the median of weekly total energy expenditure, estimated by the International Physical Activity Questionnaire (IPAQ-long version). The LI diagnosis was confirmed by lactose intolerance test (oral lactose overload with monitoring of blood glucose and associated clinical manifestations). BMD was assessed by dual energy X-ray absorptiometry (DXA). As expected, physical activity score was higher in both groups for women classified as more active (p>0.05). The BMD at hip and pelvis was lower in LI than in C group (p<0.05). In addition, there was a tendency for a lower BMD in L2, L4, femoral neck and total hip for LI compared to C group (p<0.10). However, there was no main effect of physical activity level or interaction for the BMD at any other bone sites (p<0.10). The LI group had lower (p<0.05) absolute free-fat mass, independently of physical activity level. Therefore, the results of the present study suggest that LI reduces BMD in pre-menopausal women and this reduction is independent of physical activity level.


2021 ◽  
Author(s):  
Anna Kopiczko ◽  
Joanna Cieplińska

Abstract Background In this cross-sectional study we aimed to investigate the association of physical activity level, muscle strength, body composition and smoking status with bone mineral density in adults men after spinal cord injuries. Methods The study covered 50 men after spinal cord injuries aged 35.6 ± 4.9 years (25 wheelchair rugby players and 25 without sports training). Bone mineral density was measured by densitometry. Body Mass Index and body fat percentage was calculated. Fat mass and fat-free mass were estimated from somatic. An interview method using the Global Adult Tobacco Survey. Muscle strength- maximal hand grip strength was measured using a Jamar dynamometer. Results The active men after SCI were significantly higher bone parameters BMD prox, BMC dis and prox, and T-score prox (large effect). Of all the variables analysed, the strongest relationships with bone parameters were consistently found for PA, FM, and age. The strength of bone status relationships with PA is mostly higher than that of the relationships with FM except BMD dis (F = 4.4 v. 12.4). The BMC parameter proved to be the most reliable (for both dis and prox) and the highest values of R^2 corr were found, ranging at 7–8% of the analysed set of traits exhausting the variance of this parameter. HGS and AS in years proved to be relevant only for BMD dis. Age when injury occurred (years) proved to be relevant only for T-score prox. Nonsmoking activity men after SCI had the most advantageous values of means BMD in forearm. Conclusion Despite its high injury rates, rugby can be considered a sport that has a beneficial effect on BMD. Physical activity level in the form of 5 and more years wheelchair rugby training has been shown to be the strongest factor affecting bone health. Active smoking especially in rugby players influenced lower averaged BMD values.


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