scholarly journals Leaf-inspired homeostatic cellulose biosensors

2021 ◽  
Vol 7 (16) ◽  
pp. eabe7432
Author(s):  
Ji-Yong Kim ◽  
Yong Ju Yun ◽  
Joshua Jeong ◽  
C.-Yoon Kim ◽  
Klaus-Robert Müller ◽  
...  

An incompatibility between skin homeostasis and existing biosensor interfaces inhibits long-term electrophysiological signal measurement. Inspired by the leaf homeostasis system, we developed the first homeostatic cellulose biosensor with functions of protection, sensation, self-regulation, and biosafety. Moreover, we find that a mesoporous cellulose membrane transforms into homeostatic material with properties that include high ion conductivity, excellent flexibility and stability, appropriate adhesion force, and self-healing effects when swollen in a saline solution. The proposed biosensor is found to maintain a stable skin-sensor interface through homeostasis even when challenged by various stresses, such as a dynamic environment, severe detachment, dense hair, sweat, and long-term measurement. Last, we demonstrate the high usability of our homeostatic biosensor for continuous and stable measurement of electrophysiological signals and give a showcase application in the field of brain-computer interfacing where the biosensors and machine learning together help to control real-time applications beyond the laboratory at unprecedented versatility.

Obesity Facts ◽  
2021 ◽  
pp. 1-14
Author(s):  
R. James Stubbs ◽  
Cristiana Duarte ◽  
António L. Palmeira ◽  
Falko F. Sniehotta ◽  
Graham Horgan ◽  
...  

<b><i>Background:</i></b> Effective interventions and commercial programmes for weight loss (WL) are widely available, but most people regain weight. Few effective WL maintenance (WLM) solutions exist. The most promising evidence-based behaviour change techniques for WLM are self-monitoring, goal setting, action planning and control, building self-efficacy, and techniques that promote autonomous motivation (e.g., provide choice). Stress management and emotion regulation techniques show potential for prevention of relapse and weight regain. Digital technologies (including networked-wireless tracking technologies, online tools and smartphone apps, multimedia resources, and internet-based support) offer attractive tools for teaching and supporting long-term behaviour change techniques. However, many digital offerings for weight management tend not to include evidence-based content and the evidence base is still limited. <b><i>The Project:</i></b> First, the project examined why, when, and how many European citizens make WL and WLM attempts and how successful they are. Second, the project employed the most up-to-date behavioural science research to develop a digital toolkit for WLM based on 2 key conditions, i.e., self-management (self-regulation and motivation) of behaviour and self-management of emotional responses for WLM. Then, the NoHoW trial tested the efficacy of this digital toolkit in adults who achieved clinically significant (≥5%) WL in the previous 12 months (initial BMI ≥25). The primary outcome was change in weight (kg) at 12 months from baseline. Secondary outcomes included biological, psychological, and behavioural moderators and mediators of long-term energy balance (EB) behaviours, and user experience, acceptability, and cost-effectiveness. <b><i>Impact:</i></b> The project will directly feed results from studies on European consumer behaviour, design and evaluation of digital toolkits self-management of EB behaviours into development of new products and services for WLM and digital health. The project has developed a framework and digital architecture for interventions in the context of EB tracking and will generate results that will help inform the next generation of personalised interventions for effective self-management of weight and health.


2016 ◽  
Vol 121 (12) ◽  
pp. 8523-8547 ◽  
Author(s):  
J. Weiss ◽  
V. Pellissier ◽  
D. Marsan ◽  
L. Arnaud ◽  
F. Renard
Keyword(s):  

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Benjamin P. Dean

PurposeThis inquiry aims to determine the features and mechanisms that specially enable a multiteam system (MTS) to develop ambidexterity that can deal effectively with rapid changes in dynamic environments. The MTS is an emerging organizational unit comprised of tightly integrated networks of teams that may originate from one or more firms. The inquiry also considered how an MTS can engage those features and mechanisms to maximize ambidexterity as dynamic capabilities for increased innovation and long-term adaptation under complex, volatile conditions.Design/methodology/approachThis conceptual inquiry integrates the emerging research on MTSs with theory and studies relating to ambidexterity and dynamic capabilities. This inquiry focuses on the attributes and linkages that specially characterize an MTS. It analyzes these to determine the key mechanisms and interactions enabling and engaging ambidexterity at MTS unit level.FindingsMTSs can engage powerful mechanisms for ambidexterity functioning as dynamic capabilities at meso-organizational level. The attributes and linkages that distinguish an MTS from other units enable it to deal effectively and efficiently with near-term task demands by simultaneously balancing the essential tasks of exploration and exploitation, and by being able to rapidly adapt by reconfiguring taskwork and reallocating resources as required for sustainable innovation and long-term success within a dynamic environment.Practical implicationsThis inquiry provides valuable insights for designing MTSs that are equipped with selected teams, flexible memberships, specialized skills and permeable interfaces. Autonomy for an MTS allows the unit to span internal and external organizational boundaries to gain access to new discoveries and to exchange information and material resources for increased innovation. Ambidexterity as dynamic capabilities facilitates exploitation of current resources by efficiently reconfiguring taskwork and reallocating materials for adaptation and competitive advantage.Originality/valueThis inquiry appears to represent the most integrative effort to examine the underexplored potential of MTSs for developing and engaging ambidexterity functioning as dynamic capabilities. The inquiry appears to be a first effort at articulating a concept of MTS ambidexterity distinct from organizational ambidexterity. The analysis synthesizes a systems model that guides organizational leaders and opens new opportunities for future research.


2018 ◽  
Vol 32 (4) ◽  
pp. 719-731
Author(s):  
M. Valle Santos ◽  
Rosa M. Mayoral

PurposeThe purpose of this paper is to explore self-regulated learning among university students, the role played by motivation and its impact on academic performance. This paper presents a teaching strategy aimed at self-regulation which draws on the educational value provided by the evaluation system.Design/methodology/approachThis research includes a quantitative analysis to examine the dependency relation between self-regulation, motivational orientation and academic performance. The impact of the teaching strategy on the relation between self-regulation and academic performance is also explored.FindingsThe findings indicate that self-regulation is closely linked to motivational orientation and is a determining factor in academic performance. In addition, implementing a teaching strategy focussing on self-regulation alters said relation.Practical implicationsThis research reflects the value of fostering the level of student self-regulation with a view to enhancing not only their current learning, but also the self-directed learning that will ensure professional success. The research also evidences the potential of the evaluation system for encouraging the development of self-regulation.Originality/valueThe conclusions to emerge from this research will help educators gain an awareness of the usefulness of strengthening student self-regulation and the potential offered by the evaluation system as a teaching resource. This research also merges extremely interesting elements – student self-regulation and the evaluation system – which to date have not been explored jointly.


Langmuir ◽  
2017 ◽  
Vol 33 (38) ◽  
pp. 9972-9978 ◽  
Author(s):  
Liming Wang ◽  
Chihiro Urata ◽  
Tomoya Sato ◽  
Matt W. England ◽  
Atsushi Hozumi
Keyword(s):  

2019 ◽  
Author(s):  
Emily Lasko ◽  
David Skylan Chester ◽  
Alexandra Martelli ◽  
Samuel James West ◽  
C. Nathan DeWall

Psychopathic traits predispose individuals toward antisocial behavior. Such antagonistic acts often result in 'unsuccessful’ outcomes such as incarceration. What mechanisms allow some people with relatively high levels of psychopathic traits to live ‘successful’, un-incarcerated lives, in spite of their antisocial tendencies? Using neuroimaging, we investigated the possibility that ‘successful’ psychopathic individuals exhibited greater development of neural structures that promote ‘successful’ self-regulation, focusing on the ventrolateral prefrontal cortex (VLPFC). Across two structural MRI studies of ‘successful’ participants (Study 1: N = 80 individuals in long-term romantic relationships; Study 2: N = 64 undergraduates), we observed that gray matter density in the left and right VLPFC was positively associated with psychopathic traits. These preliminary results support a compensatory model of psychopathy, in which ‘successful’ psychopathic individuals develop inhibitory mechanisms to compensate for their antisocial tendencies. Traditional models of psychopathy that emphasize deficits may be aided by such compensatory models that identify surfeits in neural and psychological processes.


Geofluids ◽  
2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Tao Qiu ◽  
Yonggang Zhang

Mud cakes are very likely to occur at the shield cutter when the shield machine passes through a clay stratum, which adhere to the cutter and reduce the excavation efficiency. Due to the thrust of the cutter, the mud cakes are compacted and cause friction at the soil-structure interface, which results in high temperature and aggravates the adhesion, and the effect tends to become stronger as the heating process lasts. In this paper, the effects of the interface temperature and the contacting time between the soil and the hot surface on the adhesion properties of the soil were studied by a self-made adhesion test device. According to the findings, at low interfacial temperature (≤40°C), both the adhesion force and the amount of adhered soil were insignificant in a short term, and the effects were found to be strengthened as the contacting time went on; at the high interfacial temperature (≥50°C), very significant soil adhesion occurred at the structure surface within a short time, and as the contacting time increased, the amount of the adhered soil decreased rapidly while the adhesion force kept increasing, and both tended to remain a constant and become independent with the temperature after a long-term contact. This study is of guiding significance for understanding the formation and development of the shield mud cakes during shield construction.


2021 ◽  
Author(s):  
Bipin Jain ◽  
Abhijeet Tambe ◽  
Dylan Waugh ◽  
Moises MunozRivera ◽  
Rianne Campbell

Abstract Several injection wells in Prudhoe Bay, Alaska exhibit sustained casing pressure (SCP) between the production tubing and the inner casing. The diagnostics on these wells have shown communication due to issues with casing leaks. Conventional cement systems have historically been used in coiled-tubing-delivered squeeze jobs to repair the leaks. However, even when these squeeze jobs are executed successfully, there is no guarantee in the short or long term that the annular communication is repaired. Many of these injector wells develop SCP in the range of 300-400 psi post-repair. It has been observed that the SCP development can reoccur immediately after annulus communication repair, or months to years after an injector well is put back on injection. Once SCP is developed the well cannot be operated further. A new generation of cement system was used to overcome the remedial challenge presented in these injector wells. This document provides the successful application of a specialized adaptive cement system conveyed to the problematic zone with the advantage of using coiled tubing equipment for optimum delivery of the remedial treatment.


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