Effect of vanadate on elevated blood glucose and depressed cardiac performance of diabetic rats

Science ◽  
1985 ◽  
Vol 227 (4693) ◽  
pp. 1474-1477 ◽  
Author(s):  
C. Heyliger ◽  
A. Tahiliani ◽  
J. McNeill
Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 1439-P
Author(s):  
IDA WIUM-ANDERSEN ◽  
RUNGBY JØRGEN ◽  
MARTIN BALSLEV ◽  
JØ RGENSEN ◽  
MERETE OSLER ◽  
...  

2018 ◽  
Vol 18 (2) ◽  
pp. 171-175
Author(s):  
Ashraf A. ◽  
Hassan F. ◽  
Batool S. ◽  
Nadeem M. ◽  
Irshad M. ◽  
...  

The objective of present study was to analyze and compare the nephroprotective effects of petroleum ether extracts of seeds of Nigella sativa and Silybum marianum in Swiss albino mice. Petroleum ether extracts of seeds of Nigella sativa and Silybum marianum were administered (200 mg kg–1) orally for 14 days following one dose of cisplatin injection (16 mg kg–1 i.p.) on 4th day. Cisplatin toxicity was identified in mice by loss of body weight, reduced triglycerides levels, elevated blood glucose, blood urea nitrogen and creatinine levels (P < 0.05). Silybum marianum and Nigella sativa significantly enhanced the body weight (9%) of diabetic rats. Silybum marianum had significantly reduced the elevated blood glucose (–106%), and BUN levels (–9%) as compared to the Nigella sativa administration. Silybum marianum extract also significantly elevated the levels of triglycerides (257%) which were much reduced after the cisplatin injection. Histological study showed that the cisplatin treated group demonstrated the necrosis signs in the glomerulus of Bowman’s capsule, hyalinization and severe cellular damage. The animals administered with extracts showed nearly normal kidney architecture, however, the kidney tissues of Silybum marianum-treated animals showed some improvement with slight signs of cellular damages.


2017 ◽  
Vol 31 (1) ◽  
pp. 101-107 ◽  
Author(s):  
Aimin Yang ◽  
Simin Liu ◽  
Ning Cheng ◽  
Hongquan Pu ◽  
Min Dai ◽  
...  

2008 ◽  
Vol 5 (2) ◽  
pp. 123-134 ◽  
Author(s):  
Hirotaka HAYASHI ◽  
Satoshi OHNO ◽  
Takanari ARAI ◽  
Masuo NAKAI ◽  
Yoshio KATO ◽  
...  

Author(s):  
Anita Nyaboke Ongosi ◽  
Calistus Wilunda ◽  
Patou Masika Musumari ◽  
Teeranee Techasrivichien ◽  
Chia-Wen Wang ◽  
...  

Kenya is experiencing a rising burden of non-communicable diseases (NCDs), yet data to inform effective interventions are limited. We investigated the prevalence of elevated blood pressure, elevated blood glucose and their determinants in a rapidly urbanizing area in Kenya. Data on socio-demographics, dietary and behavioural risk factors, anthropometric measurements, blood pressure, blood glucose, plasma lipids and urinary biomarkers were collected from 221 men and 372 women (25–64 years). Multivariable logistic regression models assessed correlates of elevated blood pressure (EBP) and elevated blood glucose (EBG). Participants’ mean age was 38.0. ± 11.1 years. The prevalence rates of pre-hypertension and hypertension were 49.0% and 31.6% in men and 43.7% and 20.1% in women, respectively, while those of pre-diabetes and diabetes were 8.4% and 8.0% in men and 11.6% and 7.4% in women, respectively. The prevalence of Body Mass Index (BMI) ≥ 25 kg/m2 was higher in women (60.2%) than in men (39.7%). However, both the risk of EBP and EBG were stronger among men than among women. The high prevalence rates of EBP, EBG and overweight/obesity coupled with low physical activity and low fruit and vegetable intake predispose this population to a higher NCD risk. Interventions to mitigate this risk considering the sex differences are urgently required.


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