Rapid Emergence of Echinocandin Resistance in Candida glabrata Resulting in Clinical and Microbiologic Failure
2013 ◽
Vol 57
(9)
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pp. 4559-4561
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Keyword(s):
ABSTRACTWe report a case ofCandida glabratacandidemia that developed resistance to micafungin within 8 days of initiation of therapy in a patient without previous echinocandin exposure or other known risk factors for clinical or microbiological failure. Pre- and postresistant isolates were confirmed to be isogenic, and sequencing of hot spots known to confer echinocandin resistance revealed a phenylalanine deletion at codon 659 withinFKS2.
2008 ◽
Vol 52
(10)
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pp. 3783-3785
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Keyword(s):
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2012 ◽
Vol 56
(12)
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pp. 6304-6309
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2013 ◽
Vol 57
(12)
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pp. 6361-6365
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Keyword(s):
2013 ◽
Vol 58
(1)
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pp. 577-580
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Keyword(s):
2013 ◽
Vol 57
(5)
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pp. 2380-2382
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Keyword(s):