Anidulafungin and Micafungin MIC Breakpoints Are Superior to That of Caspofungin for IdentifyingFKSMutant Candida glabrata Strains and Echinocandin Resistance
2013 ◽
Vol 57
(12)
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pp. 6361-6365
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Keyword(s):
ABSTRACTBy CLSI interpretive criteria, anidulafungin and micafungin MICs determined by various methods were sensitive (60 to 70%) and highly specific (94 to 100%) for identifyingFKSmutations among 120Candida glabrataisolates. Anidulafungin and micafungin breakpoints were more specific than CLSI's caspofungin breakpoint in identifyingFKSmutant strains and patients with invasive candidiasis who were likely to fail echinocandin treatment (P≤ 0.0001 for both). Echinocandin MICs were most useful clinically when interpreted in the context of prior echinocandin exposure.
2008 ◽
Vol 52
(10)
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pp. 3783-3785
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Keyword(s):
Keyword(s):
2012 ◽
Vol 56
(12)
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pp. 6304-6309
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2013 ◽
Vol 57
(9)
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pp. 4559-4561
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Keyword(s):
2013 ◽
Vol 57
(8)
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pp. 3528-3535
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2014 ◽
Vol 58
(12)
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pp. 7601-7605
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