Sterol and Fatty Acid Composition of Candida lusitaniae Clinical Isolates
2002 ◽
Vol 46
(2)
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pp. 531-533
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Keyword(s):
ABSTRACT The sterol and fatty acid compositions of four amphotericin B-resistant and of two amphotericin B-susceptible Candida lusitaniae clinical isolates were determined. A flow cytofluorometric susceptibility test (FCST) with a membrane potential-sensitive cationic dye was used as a complement to the conventional method for selecting the isolates. Compared to susceptible isolates, resistant ones showed a greatly reduced ergosterol content and changes in sterol composition, consistent with a defect in Δ8→7 isomerase. Within each group, no correlation between the sterol or fatty acid pattern or composition and both the degree of in vitro susceptibility and FCST MIC was found.
2001 ◽
Vol 48
(6)
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pp. 919-921
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1996 ◽
Vol 42
(9)
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pp. 960-964
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2001 ◽
Vol 43
(5)
◽
pp. 267-270
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1997 ◽
Vol 41
(2)
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pp. 233-235
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2002 ◽
Vol 46
(4)
◽
pp. 1032-1037
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2002 ◽
Vol 6
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pp. S45-S46
Keyword(s):