The yjeQ Gene Is Required for Virulence of Staphylococcus aureus
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ABSTRACT Gene products required for in vivo growth and survival of Staphylococcus aureus and other pathogens represent new targets for antimicrobial chemotherapy. In this study we created a Staphylococcus aureus yjeQ deletion strain and tested its virulence using a mouse kidney abscess infection model. The yjeQ deletion strain was compromised for growth in vitro and severely attenuated for virulence. We concluded that yjeQ is an attractive and novel new drug target.
2001 ◽
Vol 69
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pp. 159-169
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2010 ◽
Vol 54
(12)
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pp. 5115-5119
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2009 ◽
Vol 53
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pp. 1463-1467
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2021 ◽
Vol 31
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1993 ◽
Vol 61
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pp. 1853-1858
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