Frequency of vacA Genotypes and Cytotoxin Activity in Helicobacter pylori Associated with Low-Grade Gastric  Mucosa-Associated Lymphoid Tissue Lymphoma

The vacA genotypes s1,m1 and s1,m2 were detected in 44 and 30% of Helicobacter pylori isolates, respectively, from patients with gastric mucosa-associated lymphoid tissue lymphoma, compared to 26 and 56% of isolates, respectively, from individuals with gastritis. The vacA s1 genotype was significantly associated with, but not predictive of, the presence of vacuolating cytotoxin activity.

Download Full-text

Nuclear expression of BCL10 or nuclear factor kappa B helps predict Helicobacter pylori-independent status of low-grade gastric mucosa-associated lymphoid tissue lymphomas with or without t(11;18)(q21;q21)

Blood ◽

10.1182/blood-2005-01-0004 ◽

2005 ◽

Vol 106 (3) ◽

pp. 1037-1041 ◽

Cited By ~ 47

Author(s):

K.-H. Yeh

Keyword(s):

Helicobacter Pylori ◽

Gastric Mucosa ◽

Lymphoid Tissue ◽

Nuclear Factor Kappa B ◽

Low Grade ◽

Nuclear Factor ◽

Nuclear Expression ◽

Nuclear Factor Kappa

Download Full-text

Immune response in Helicobacter pylori-induced low-grade gastric-mucosa-associated lymphoid tissue (MALT) lymphoma

Journal of Medical Microbiology ◽

10.1099/jmm.0.05348-0 ◽

2004 ◽

Vol 53 (1) ◽

pp. 21-29 ◽

Cited By ~ 13

Author(s):

Rie Yamasaki ◽

Kenji Yokota ◽

Hiroyuki Okada ◽

Shyunji Hayashi ◽

Motowo Mizuno ◽

...

Keyword(s):

Immune Response ◽

Helicobacter Pylori ◽

Gastric Mucosa ◽

Malt Lymphoma ◽

Lymphoid Tissue ◽

Low Grade

Download Full-text

Endoscopic characteristics of low-grade gastric mucosa-associated lymphoid tissue lymphoma after eradication of Helicobacter pylori

Journal of Gastroenterology and Hepatology ◽

10.1046/j.1440-1746.2000.02317.x ◽

2000 ◽

Vol 15 (10) ◽

pp. 1113-1119 ◽

Cited By ~ 13

Author(s):

Yoshihito Urakami ◽

Toshiaki Sano ◽

Shahnaz Begum ◽

Hideko Endo ◽

Hitoshi Kawamata ◽

...

Keyword(s):

Helicobacter Pylori ◽

Gastric Mucosa ◽

Lymphoid Tissue ◽

Low Grade ◽

Endoscopic Characteristics

Download Full-text

First-line antibiotic therapy in Helicobacter pylori-negative low-grade gastric mucosa-associated lymphoid tissue lymphoma

Scientific Reports ◽

10.1038/s41598-017-14102-8 ◽

2017 ◽

Vol 7 (1) ◽

Cited By ~ 5

Author(s):

Sung-Hsin Kuo ◽

Kun-Huei Yeh ◽

Ming-Shiang Wu ◽

Chung-Wu Lin ◽

Ming-Feng Wei ◽

...

Keyword(s):

Helicobacter Pylori ◽

Gastric Mucosa ◽

Antibiotic Therapy ◽

Lymphoid Tissue ◽

Low Grade ◽

First Line

Download Full-text

Low-grade gastric mucosa-associated lymphoid tissue lymphoma: Clinicopathological factors associated with Helicobacter pylori eradication and tumor regression.

Journal of Clinical Oncology ◽

10.1200/jco.2020.38.4_suppl.353 ◽

2020 ◽

Vol 38 (4_suppl) ◽

pp. 353-353

Author(s):

Hyun Ik Shim ◽

Dong Ho Lee ◽

Jae Ho Cho ◽

Cheol Min Shin ◽

Hyuk Yoon ◽

...

Keyword(s):

Helicobacter Pylori ◽

Gastric Mucosa ◽

Malt Lymphoma ◽

Lymphoid Tissue ◽

Tumor Regression ◽

Neutrophil Infiltration ◽

Tumor Location ◽

Gastric Malt Lymphoma ◽

Low Grade ◽

H Pylori

353 Background: Eradication of Helicobacter pylori is widely accepted as the initial therapy for low-grade gastric mucosa-associated lymphoid tissue (MALT) lymphoma. The aim of this study was to assess the remission and relapse rates of low-grade gastric MALT lymphoma after H. pylori eradication and to identify the clinical factors affecting remission. Methods: We retrospectively analyzed 151 patients diagnosed with gastric MALT lymphoma from May 2003 to December 2018. Results: Of the 151 patients, 112 (74.2%) had an H. pylori infection. Total regression rates with eradication was 90.2% (101/112) in H. pylori-positive patients and 55% (11/20) in H. pylori-negative patients. Age, sex, tumor location, endoscopic findings, and the severity of mononuclear lymphocytes were not related to achieving successful initial H. pylori eradication and remission. However, patients with a smaller H. pylori burden ( p=0.030) and less neutrophil infiltration ( p=0.003) were more likely to achieve a successful initial H. pylori eradication. H. pylori ( p<0.001) and the burden ( p=0.020) were significantly related to remission of MALT lymphoma. Conclusions: The results show that H. pylori burden and neutrophil infiltration were inversely related to the success of the initial H. pylori eradication procedure and that the H. pylori burden was inversely related to the remission of MALT lymphoma.

Download Full-text