The human transforming growth factor alpha promoter directs transcription initiation from a single site in the absence of a TATA sequence
1988 ◽
Vol 8
(12)
◽
pp. 5549-5554
Keyword(s):
Transforming growth factor alpha (TGF-alpha) is a transformation-responsive mitogenic polypeptide that is expressed in the brain, epithelial cells, and activated macrophages. We isolated and characterized the TGF-alpha promoter and localized the 5' end of the TGF-alpha transcript to a unique position. Surprisingly, no apparent TATA box was present in the promoter sequence, suggesting that transcription from mammalian genes can initiate at unique and specific positions from promoters lacking this sequence motif.
1988 ◽
Vol 8
(12)
◽
pp. 5549-5554
◽
1994 ◽
Vol 269
(40)
◽
pp. 25057-25061
◽
1990 ◽
Vol 265
(8)
◽
pp. 4578-4582
◽
Activation of cytosolic phospholipase A2 by transforming growth factor-alpha in HEL-30 keratinocytes
1993 ◽
Vol 268
(22)
◽
pp. 16795-16802
1990 ◽
Vol 265
(2)
◽
pp. 1016-1020
1993 ◽
Vol 268
(25)
◽
pp. 19143-19151
2012 ◽
Vol 29
(6)
◽
pp. 539-548
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Keyword(s):
1988 ◽
Vol 8
(3)
◽
pp. 1247-1252
◽