scholarly journals Reducing the Periplasmic Glutathione Content Makes Escherichia coli Resistant to Trimethoprim and Other Antimicrobial Drugs

Author(s):  
Yajing Song ◽  
Zhen Zhou ◽  
Jing Gu ◽  
Junmei Yang ◽  
Jiaoyu Deng

After being used extensively for decades, trimethoprim still remains one of the key accessible antimicrobials recommended by the World Health Organization. A better understanding of the mechanisms of resistance would be beneficial for the future utilization of this drug.

2005 ◽  
Vol 20 (6) ◽  
pp. 382-384 ◽  
Author(s):  
Poonam Khetrapal Singh ◽  
Roderico Ofrin ◽  
P. Ravindran ◽  
Idrus Paturussi ◽  
Ibrahim Yasir ◽  
...  

AbstractThis is a summary of the presentations and discussion of Session 1.2 of the Conference, Health Aspects of the Tsunami Disaster in Asia, convened by the World Health Organization (WHO) in Phuket, Thailand, 04–06 May 2005. The topics discussed included issues related national health perspectives as pertaining to the responses to the damage created by the Tsunami. It is presented in the following major sections: (1) key questions; (2) discussion; (3) what was done well?; (4) what could have been done better?; and (5) what can be done to prepare for the future?.


2020 ◽  
Vol 15 (4) ◽  
pp. 520-529
Author(s):  
Donald Lien ◽  
Joseph Kortsch

Summary The purpose of this essay is to discuss the ramifications of the 2020 COVID-19 pandemic on the future of the World Health Organization (WHO). In particular, the WHO has come under fire for its initial response and reporting of the pandemic, its acceptance of Chinese self-reporting and management of the crisis and dubious claims that it failed to acknowledge and respond to data from Taiwan that indicated human–to-human transmission was occurring. These alleged missteps have brought unwanted and intense international scrutiny on the organisation and have, perhaps, left its future uncertain. This essay examines the history and mandate of the WHO, its vulnerability to national and regional political movements and some likely outcomes for the near- and long-term future. Additionally, it briefly addresses how the WHO is used as a diplomatic surrogate for the UN, especially in matters relating to Taiwan.


Author(s):  
Robert Paarlberg

In the future, will obesity continue to replace hunger as the world’s most serious food problem? In terms of the numbers affected, yes. In 2008, according to the World Health Organization, 500 million adults globally over the age of 20 were technically obese. If we...


Author(s):  
Prateek Pandey ◽  
Ratnesh Litoriya

ABSTRACT As per the World Health Organization (WHO)[1], COVID-19 cases continue to surge, and the world must learn from this disaster. Most of the world economies are shattered due to this pandemic. The development of infrastructure to counter such deadly viral attacks in the future is the wisest investment that can be made. Another report from WHO [2] says that the elderly population is the most vulnerable section affected by the pandemic, and the threat to their life becomes manifold if they are living alone. Thus a well-formed elderly support framework is required to safeguard the vulnerable from COVID like disasters in the future. We report here on the research findings we conducted by laying out a mitigation system for elderly wellbeing during disastrous times. The proposed system demands a sound collaboration between software, hardware devices, the state, and social agencies.


2020 ◽  
Vol 7 (3) ◽  
pp. 203
Author(s):  
Yamin Yaddi ◽  
Safika Safika ◽  
Fachriyan Hasmi Pasaribu

ABSTRAKPermasalahan resistensi Antibiotika pada hewan kesayangan menjadi kendala kesehatan hewan di seluruh dunia. World Health Organisation (WHO) menyebutkan bahwa pada masa mendatang resistensi antibiotika akan menjadi tantangan yang terbesar dalam dunia kesehatan. Penelitian ini bertujuan untuk mengukur tingkat resistensi antibiotika terhadap Escherichia coli yang diisolasi dari kucing pada klinik hewan di Kota Bogor. Hasil penelitian menunjukan bahwa resistensi Escherichia coli tertinggi terjadi pada golongan β-laktam (ampisilin 66% dan amoksisilin 60%) yang diikuti oleh golongan tetrasiklin (oksitetrasiklin 54% dan dosisiklin 24%), serta golongan kuinolon (enrofloksasin 38% dan ciprofloksasin 28%). Hasil dari penelitian ini diharapkan dapat menjadi pertimbangan medis bagi praktisi hewan kesayangan dalam penggunaan antibiotika.Kata Kunci: Escherichia coli, klinik hewan, kucing, resistensi antibiotikaABSTRACTThe problem of antibiotic resistance in pets is obstacles to animal health throughout the world. World Health Organization (WHO) states that in the future, antibiotic resistance will become the biggest challenge in the health concern. This study aims to measure the level of Escherichia coli resistance to antibiotics which is isolated from cats on veterinary clinics in Bogor City. The results showed that the highest resistance of Escherichia coli occurred in the β-lactam group (ampicillin 66% and amoxicillin 60%) followed by tetracycline (oxytetracycline 54% and doxycycline 24%), and quinolone group (enrofloxacin 38% and ciprofloxacin 28%). This study is expected to become medical considerations for pet practitioners in the use of antibiotics.Keywords: animal clinic, antibiotic resistance, cats, Escherichia coli


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