2-Isothiocyanatobenzylpyridinium bromide - An intermediate for the synthesis of 2-arylamino-4H-benzo[d][1,3]thiazines
1986 ◽
Vol 51
(12)
◽
pp. 2810-2816
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2-Bromomethylphenyl isothiocyanate reacts with pyridine to yield 2-isothiocyanatobenzylpyridinium bromide, which afforded N-aryl-N'-(2-benzylpyridinium)thiourea bromides. Deprotonization of the latter with aqueous NaOH gave N-aryl-N'-(2-benzylpyridinium) thioureates; these freed pyridine upon heating to give 2-arylamino-4H-benzo[d][1,3]thiazines. Structure of these compounds was evidenced by IR, 1H, 13C NMR and mass spectral data and backed by elemental analysis.
2015 ◽
Vol 49
◽
pp. 99-103
2015 ◽
Vol 50
◽
pp. 35-42
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