Overview of the Relevant Literature on the Possible Role of Acupuncture in Treating Male Sexual Dysfunction

2014 ◽  
Vol 32 (5) ◽  
pp. 406-410 ◽  
Author(s):  
Ming-Yen Tsai ◽  
Chun-Ting Liu ◽  
Cheng-Chieh Chang ◽  
Shih-Yu Chen ◽  
Sheng-Teng Huang
Keyword(s):  
Sexual Dysfunction ◽  
Premature Ejaculation ◽  
Relevant Literature ◽  
Case Series ◽  
Sham Acupuncture ◽  
Risk Of Bias ◽  
Inclusion Criteria ◽  
Male Sexual Dysfunction ◽  
Randomised Controlled

Objective To systematically review scientific reports on the effectiveness of acupuncture to treat male sexual dysfunction. Methods The Medline database was searched for published clinical trials of acupuncture for erectile dysfunction (ED) and premature ejaculation (PE) with English abstracts. Risk of bias was assessed for randomised controlled trials (RCTs). Results Seven studies on two conditions of male sexual dysfunction met the inclusion criteria. Three out of four RCTs were patient-blinded, but all had a high risk of bias. Three suggested that acupuncture has a therapeutic effect as compared with sham acupuncture. Comparisons with paroxetine were inconsistent. Other uncontrolled studies and case series suggested satisfactory improvements of ED and PE after acupuncture. Conclusions Acupuncture appears to have promise for treating male sexual dysfunction, but in view of the small number of studies and their variable quality, doubts remain about its effectiveness. Further studies are justified.

scholarly journals A Late COVID-19 Complication: Male Sexual Dysfunction

2020 ◽  
Vol 35 (6) ◽  
pp. 688-689
Author(s):  
Saeed Shoar ◽  
Siamak Khavandi ◽  
Elsa Tabibzadeh ◽  
Aydin Vaez ◽  
Ali Khabbazi Oskouei ◽  
...  
Keyword(s):  
Infectious Disease ◽  
Sexual Dysfunction ◽  
Clinical Course ◽  
Urogenital System ◽  
Multiple Organs ◽  
Clinical Presentations ◽  
Male Sexual Dysfunction ◽  
Male Patients ◽  
Novel Coronavirus

AbstractSince the beginning of the coronavirus infectious disease 2019 (COVID-19) pandemic, an exponentially large amount of data has been published to describe the pathology, clinical presentations, and outcomes in patients infected with the severe acute respiratory syndrome novel coronavirus 2 (SARS-CoV-2). Although COVID-19 has been shown to cause a systemic inflammation predisposing the involvement of multiple organs, its mechanism affecting the urogenital system has not been well-documented. This case report presents the clinical course of two male patients with COVID-19 who developed sexual dysfunction, as anorgasmia, following recovery from the infection. Although no evidence of viral replication or inflammatory involvement could be identified in these cases’ urogenital organs, a lack of other known risk factors for anorgasmia points to the role of COVID-19 as the contributing factor.

scholarly journals P416 Results of the first paediatric randomised controlled trial of faecal microbiota transplant for ulcerative colitis

2020 ◽  
Vol 14 (Supplement_1) ◽  
pp. S379-S380
Author(s):  
N Pai ◽  
J Popov ◽  
L Hill ◽  
E Hartung ◽  
K Grzywacz ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Clinical Response ◽  
Healthy Donor ◽  
Activity Index ◽  
Case Reports ◽  
Case Series ◽  
Faecal Microbiota ◽  
Open Label ◽  
Randomised Controlled

Abstract Background The role of faecal microbiota transplant (FMT) for the treatment of ulcerative colitis (UC) has been reported across 4 randomised-controlled trials (RCT) in adults. Promising data have emerged from small, open-label paediatric case series and case reports but a proper blinded, placebo-controlled RCT has not been described in children. We report results from the first multicentre RCT of FMT in paediatric UC patients, conducted over 36 months in Ontario and Quebec, Canada. Methods We enrolled 25 children, ages 4–17 years old with active UC across two tertiary IBD clinics. Patients had active inflammation and remained on stable doses of medication at entry. Blinded participants received enemas containing healthy donor stool (active) or normal saline (placebo), 2×/week for 6 weeks. Faecal calprotectin (fCal), C-reactive protein (CRP), and paediatric ulcerative colitis activity index (PUCAI) scores were compared between groups during intervention, and at four follow-up time points over 30 weeks. Donor and recipient stools were measured for 16s rRNA and metagenomics analyses. Results In intention-to-treat (ITT) analysis, FMT (n = 13) at 6 weeks was more likely to improve clinical response (OR 9.3, 95% CI [0.7, 122.6]), CRP (OR 4.7, 95% CI [0.8, 28.4]), and fCal (OR 13.3, 95% CI [1.1, 166.4]) from baseline compared with placebo (n = 12). FMT at 30 weeks was also more likely than placebo to improve clinical response, CRP, and fCal (Table 1). In ITT analysis of the open-label arm (n = 7), FMT at 6 weeks and 30 weeks decreased CRP (−42.9%, −28.6%), fCal (−28.6%, −42.9%), and PUCAI score (−14.3%, −42.9%) from baseline. Conclusion Serial FMT enemas containing healthy donor microbiota led to greater improvements in serum and stool inflammatory markers, and rates of clinical response, in paediatric patients with active UC compared with placebo. These improvements largely persisted beyond 6 months after final FMT treatment. This study offers the strongest preliminary evidence, from a blinded, placebo-controlled multicentre RCT for the role of FMT in the management of paediatric UC.

Should the duration of head bandaging be reduced after pinnaplasty? A systematic review

2014 ◽  
Vol 128 (11) ◽  
pp. 948-951 ◽  
Author(s):  
A E L McMurran ◽  
I Khan ◽  
S Mohamad ◽  
M Shakeel ◽  
H Kubba
Keyword(s):  
Systematic Review ◽  
Randomised Controlled Trials ◽  
Case Series ◽  
Cochrane Library ◽  
Controlled Trials ◽  
Inclusion Criteria ◽  
National Library ◽  
Significant Difference ◽  
Randomised Controlled ◽  
The Cochrane Library

AbstractBackground:It is common practice to use head bandages for 7–10 days following pinnaplasty. However, head bandages are often troublesome for patients and can lead to serious complications.Method:A systematic review was performed to evaluate the use of head bandages after pinnaplasty. A search of Medline, Embase (Ovid) and CINAHL (EBSCO collections), the Cochrane Library, Pubmed (US National Library of Medicine) and Google Scholar identified 34 related articles. Of these, 14 were deemed relevant and 2 randomised controlled trials, 1 cohort study, 3 case series and 1 literature review met the inclusion criteria.Results:The two randomised controlled trials show no statistically significant difference in complications when a head bandage was used for the standard 7–10 days, for 24 hours or not at all. The three case series show that using a head bandage for 24 hours or not at all are safe alternatives. The review article recommended that when head bandages are applied after pinnaplasty it should be for the shortest duration possible.Conclusion:Based on the available evidence, not using a head bandage at all or using one for a maximum of 24 hours following pinnaplasty is recommended.

Verum versus Sham Manual Acupuncture for Migraine: A Systematic Review of Randomised Controlled Trials

2016 ◽  
Vol 34 (2) ◽  
pp. 76-83 ◽  
Author(s):  
Yan Yang ◽  
Qinghui Que ◽  
Xiaode Ye ◽  
Guo hua Zheng
Keyword(s):  
Systematic Review ◽  
Recurrence Rate ◽  
Randomised Controlled Trials ◽  
Total Effective Rate ◽  
Effective Rate ◽  
Sham Acupuncture ◽  
Risk Of Bias ◽  
Controlled Trials ◽  
Manual Acupuncture ◽  
Randomised Controlled

Background Manual acupuncture (MA) is commonly used as a treatment for migraine in China. However, its specific clinical effects have been challenged on the basis that some of its effects may relate to psychological or ‘placebo’ mechanisms. Objective To identify the effectiveness of verum MA compared with sham acupuncture for the treatment of migraine. Methods Eight electronic databases were searched for randomised controlled trials (RCTs) evaluating the effect of verum versus sham MA on migraine. The quality of included trials was assessed using the ‘risk of bias’ tool provided by the Cochrane Handbook for Systematic Review of Intervention. RevMan 5.2 software was used for data analysis. Results Ten trials with 997 participants were included. Most trials had high methodological quality and were at low risk of bias. Meta-analysis showed superior effects of verum MA over sham acupuncture on the total effective rate, reflected by a reduction in the ‘not effective’ rate (relative risk (RR) 0.24, 95% CI 0.15 to 0.38; p<0.0001, four trials) and a reduced recurrence rate (RR 0.47, 95% CI 0.28 to 0.81; p=0.006, two trials), but no significant differences in headache intensity, frequency or duration, accompanying symptoms and use of medication. No severe adverse events related to acupuncture occurred during treatment with either verum or sham MA. Conclusions Current clinical evidence suggests that verum acupuncture is superior to sham acupuncture in migraine, reflected by a higher total effective rate and decreased recurrence rate. Nevertheless, further large-scale RCTs with a rigorous design are required to confirm these findings in view of the relative paucity of eligible RCTs and small sample sizes of those included.

scholarly journals A protocol for rapid evidence synthesis into soil loosening as an intervention to ameliorate compaction caused by dairy farming and the impacts of this for productivity and sustainability

2018 ◽  
Author(s):  
Helen Kendall ◽  
Amy Taylor ◽  
Mark Reed ◽  
Gavin Stewart
Keyword(s):  
Search Strategy ◽  
Data Extraction ◽  
Evidence Synthesis ◽  
Meta Analysis ◽  
Relevant Literature ◽  
Risk Of Bias ◽  
Rapid Review ◽  
Dairy Production ◽  
Inclusion Criteria ◽  
Data Synthesis

This is a protocol for a rapid review of the effectiveness of soil loosening to ameliorate compaction caused by cattle treading from dairy production on UK dairy farms. The review will synthesise relevant literature that explores the impacts that can be derived from mechanical soil loosening for improved soil quality, productivity (i.e. yield) and the environment. The protocol outlines the rationale, objectives, inclusion criteria, search strategy and screening processes for the meta-analysis, and the plans for data extraction, risk of bias and data synthesis approaches.

Integrative Treatment of Male Sexual Dysfunction (DRAFT)

2018 ◽  
Author(s):  
Jeffrey A. Albaugh
Keyword(s):  
Erectile Dysfunction ◽  
Patient Education ◽  
Sexual Dysfunction ◽  
Premature Ejaculation ◽  
Treatment Options ◽  
Medical Treatments ◽  
Health Goals ◽  
Medicinal Treatment ◽  
Male Sexual Dysfunction ◽  
Pros And Cons

Male sexual dysfunction is common and may include hypoactive sexual desire disorders/lack of libido, premature ejaculation, decreased ability to climax or orgasm, erectile dysfunction, and/or Peyronie’s disease. There are a myriad of cognitive behavioral, integrative, and traditional medicinal treatment options available. Each treatment has pros and cons. Patient education prior to deciding on a treatment is key. Individual patients need to understand the good and bad of each treatment to make an informed decision about how they want to meet their sexual health goals. Traditional medical treatments were discussed in Chapter 4. The aim of this chapter is to describe other nonmedicinal, nonsurgical treatment options for male sexual dysfunction.

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