scholarly journals Evaluation of the genetic overlap between osteoarthritis with body mass index and height using genome-wide association scan data

2012 ◽  
Vol 72 (6) ◽  
pp. 935-941 ◽  
Author(s):  
Katherine S Elliott ◽  
Kay Chapman ◽  
Aaron Day-Williams ◽  
Kalliope Panoutsopoulou ◽  
Lorraine Southam ◽  
...  
2018 ◽  
Vol 1 (1) ◽  
Author(s):  
Emma A. D. Clifton ◽  
John R. B. Perry ◽  
Fumiaki Imamura ◽  
Luca A. Lotta ◽  
Soren Brage ◽  
...  

2015 ◽  
Vol 22 (2) ◽  
pp. 535-549 ◽  
Author(s):  
Renato Polimanti ◽  
Huiping Zhang ◽  
Andrew H. Smith ◽  
Hongyu Zhao ◽  
Lindsay A. Farrer ◽  
...  

2015 ◽  
Vol 44 (2) ◽  
pp. 700-712 ◽  
Author(s):  
N. M. Warrington ◽  
L. D. Howe ◽  
L. Paternoster ◽  
M. Kaakinen ◽  
S. Herrala ◽  
...  

2018 ◽  
Vol 27 (20) ◽  
pp. 3641-3649 ◽  
Author(s):  
Loic Yengo ◽  
Julia Sidorenko ◽  
Kathryn E Kemper ◽  
Zhili Zheng ◽  
Andrew R Wood ◽  
...  

2017 ◽  
Vol 49 (10) ◽  
pp. 1458-1467 ◽  
Author(s):  
Masato Akiyama ◽  
Yukinori Okada ◽  
Masahiro Kanai ◽  
Atsushi Takahashi ◽  
Yukihide Momozawa ◽  
...  

2007 ◽  
Vol 8 (Suppl 1) ◽  
pp. S18 ◽  
Author(s):  
Caroline S Fox ◽  
Nancy Heard-Costa ◽  
L Adrienne Cupples ◽  
Josée Dupuis ◽  
Ramachandran S Vasan ◽  
...  

2011 ◽  
Vol 9 (2) ◽  
pp. 59-63
Author(s):  
Hae-In Lee ◽  
Jae-Jung Kim ◽  
Tae-Sung Park ◽  
Kyung-A Kim ◽  
Jong-Eun Lee ◽  
...  

2010 ◽  
Vol 13 (2) ◽  
pp. 179-193 ◽  
Author(s):  
Jimmy Z. Liu ◽  
Sarah E. Medland ◽  
Margaret J. Wright ◽  
Anjali K. Henders ◽  
Andrew C. Heath ◽  
...  

AbstractHuman height and body mass index are influenced by a large number of genes, each with small effects, along with environment. To identify common genetic variants associated with these traits, we performed genome-wide association studies in 11,536 individuals composed of Australian twins, family members, and unrelated individuals at ∼550,000 genotyped SNPs. We identified a single genome-wide significant variant for height (Pvalue = 1.06 × 10–9) located inHHIP, a well-replicated height-associated gene. Suggestive levels of association were found for other known genes associated with height (Pvalues < 1 × 10–6):ADAMTSL3,EFEMP1,GPR126, andHMGA2; and BMI (Pvalues < 1 × 10–4):FTOandMC4R. Together, these variants explain less than 2% of total phenotypic variation for height and 0.5% for BMI.


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