The influence of discrepant imaging judgements on the classification of axial spondyloarthritis is limited: a replication in the SpondyloArthritis Caught Early (SPACE) cohort

2017 ◽  
Vol 77 (1) ◽  
pp. e1-e1 ◽  
Author(s):  
Zineb Ez-Zaitouni ◽  
Miranda van Lunteren ◽  
Pauline A C Bakker ◽  
Rosaline van den Berg ◽  
Monique Reijnierse ◽  
...  
Keyword(s):  
Axial Spondyloarthritis

Can we use structural lesions seen on MRI of the sacroiliac joints reliably for the classification of patients according to the ASAS axial spondyloarthritis criteria? Data from the DESIR cohort

2016 ◽  
Vol 76 (2) ◽  
pp. 392-398 ◽  
Author(s):  
Pauline A C Bakker ◽  
Rosaline van den Berg ◽  
Gregory Lenczner ◽  
Fabrice Thévenin ◽  
Monique Reijnierse ◽  
...  
Keyword(s):  
New York ◽  
Back Pain ◽  
Axial Spondyloarthritis ◽  
The Other ◽  
Inflammatory Back Pain ◽  
Symptom Duration ◽  
Sacroiliac Joints

ObjectivesInvestigating the utility of adding structural lesions seen on MRI of the sacroiliac joints to the imaging criterion of the Assessment of SpondyloArthritis (ASAS) axial SpondyloArthritis (axSpA) criteria and the utility of replacement of radiographic sacroiliitis by structural lesions on MRI.MethodsTwo well-calibrated readers scored MRI STIR (inflammation, MRI-SI), MRI T1-w images (structural lesions, MRI-SI-s) and radiographs of the sacroiliac joints (X-SI) of patients in the DEvenir des Spondyloarthrites Indifférenciées Récentes cohort (inflammatory back pain: ≥3 months, <3 years, age <50). A third reader adjudicated MRI-SI and X-SI discrepancies. Previously proposed cut-offs for a positive MRI-SI-s were used (based on <5% prevalence among no-SpA patients): erosions (E) ≥3, fatty lesions (FL) ≥3, E/FL ≥5. Patients were classified according to the ASAS axSpA criteria using the various definitions of MRI-SI-s.ResultsOf the 582 patients included in this analysis, 418 fulfilled the ASAS axSpA criteria, of which 127 patients were modified New York (mNY) positive and 134 and 75 were MRI-SI-s positive (E/FL≥5) for readers 1 and 2, respectively. Agreement between mNY and MRI-SI-s (E/FL≥5) was moderate (reader 1: κ: 0.39; reader 2: κ: 0.44). Using the E/FL≥5 cut-off instead of mNY classification did not change in 478 (82.1%) and 469 (80.6%) patients for readers 1 and 2, respectively. Twelve (reader 1) or ten (reader 2) patients would not be classified as axSpA if only MRI-SI-s was performed (in the scenario of replacement of mNY), while three (reader 1) or six (reader 2) patients would be additionally classified as axSpA in both scenarios (replacement of mNY and addition of MRI-SI-s). Similar results were seen for the other cut-offs (E≥3, FL≥3).ConclusionsStructural lesions on MRI can be used reliably either as an addition to or as a substitute for radiographs in the ASAS axSpA classification of patients in our cohort of patients with short symptom duration.

Value of high-sensitivity C-reactive protein for classification of early axial spondyloarthritis: results from the DESIR cohort

2013 ◽  
Vol 72 (5) ◽  
pp. 785-786 ◽  
Author(s):  
Victoria Navarro-Compán ◽  
Désirée van der Heijde ◽  
Bernard Combe ◽  
Claudine Cosson ◽  
Floris A van Gaalen
Keyword(s):  
Axial Spondyloarthritis ◽  
High Sensitivity ◽  
C Reactive Protein ◽  
Reactive Protein

scholarly journals Axial spondyloarthritis: a current look at the concept and evolution of the disease

2019 ◽  
Vol 13 (4) ◽  
pp. 4-10 ◽  
Author(s):  
D. G. Rumyantseva ◽  
Sh. F. Erdes
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Axial Spondyloarthritis ◽  
Current Concept ◽  
Resonance Imaging ◽  
A Current

The article provides data on the terminology and classification of spondyloarthritis (SpA) and highlights the current concept of axial SpA (axSpA). It gives the comparative characteristics of international cohorts of patients with axSpA. The review describes the role of magnetic resonance imaging and radiography in the diagnosis and study of the evolution of axSpA.

Diagnosis and classification of axial spondyloarthritis

2016 ◽  
Author(s):  
Floris van Gaalen ◽  
Désirée van der Heijde ◽  
Maxime Dougados
Keyword(s):  
Chronic Back Pain ◽  
Axial Spondyloarthritis ◽  
Chronic Inflammatory Disease ◽  
Disease Classification ◽  
Laboratory Features ◽  
Bone Changes ◽  
Diagnosis And Classification ◽  
The Difference ◽  
Magnetic Resonance Imaging Mri

Axial spondyloarthritis (axSpA) is a potentially disabling chronic inflammatory disease affecting the spine and sacroiliac (SI) joints. Lead symptoms are chronic back pain and stiffness. The disease is called radiographic axSpA or ankylosing spondylitis (AS) when, on plain radiographs, bone changes consistent with sacroiliitis are present. When no evidence of sacroiliitis is seen on radiographs, it is called non-radiographic axSpA. In such cases, diagnosis is made based on evidence of active inflammation of SI joints on magnetic resonance imaging (MRI) and clinical and laboratory features, or a combination of clinical and laboratory features only. Apart from affecting the spine and SI joints, axSpA may involve peripheral joints (e.g. knee, ankle) and manifest in extra-articular manifestations, for example uveitis, psoriasis, and inflammatory bowel disease. In this chapter, diagnosis and classification of axSpA is discussed, including use of MRI in detecting sacroiliitis and the difference between clinical diagnosis and disease classification.

scholarly journals Gender Differences in Disease Activity and Impact in Axial Spondyloarthritis

2021 ◽  
pp. jrheum.210564
Author(s):  
Ying-Ying Leung
Keyword(s):  
Gender Differences ◽  
Back Pain ◽  
Ankylosing Spondylitis ◽  
Disease Activity ◽  
International Society ◽  
Axial Spondyloarthritis ◽  
Classification Criteria ◽  
Inflammatory Back Pain

Ankylosing spondylitis (AS), characterized by inflammatory back pain and sacroiliitis on radiography, was traditionally considered a condition predominant in men. Since the introduction of the 2009 Assessment in Spondyloarthritis international Society classification criteria1 aiming to facilitate earlier classification of cases without radiographic sacroiliitis, more women have been classified as having axial spondyloarthritis (axSpA).

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