scholarly journals AB0869-HPR HOW TO IMPROVE THE QUALITY-OF-LIFE IN PATIENTS WITH OSTEOPOROSIS?

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1458.2-1458
Author(s):  
A. Lammert ◽  
S. Lezhenina ◽  
N. Shuvalova ◽  
N. Andreeva ◽  
E. Guryanova

Background:This paper is an assessment of quality-of-life for patients living with osteoporosis. It employs special questionnaires and scales to allow for more detailed observation of the patient both during initial treatment and in dynamics. This allows us to establish the effectiveness of the therapy, to assess the need to correct the treatment and rehabilitation program, and to compare the effectiveness of various treatment methods and determine disease prognosis.Objectives:to assess quality-of-life in patients with osteoporosis for further development of treatment and rehabilitation programs.Methods:To assess the quality-of-life in patients with osteoporosis, HRQOL and SF-36 scale were used. The study was conducted from January to December 2019, at the Republican Clinical Hospital of the Chuvash Republic. The study involved 70 patients (n = 70) with a diagnosis of osteoporosis with a pathological fracture. Of the 70 patients included in the study, 35 women aged 67 ± 1.2 years and 35 men aged 60 ± 1.2 years. The results were statistically processed using MS Office Excel programs.Results:According to the analysis carried out by the HRQOL method, more than half of the patients (52.13%) experienced daily back pain, which worsens their mood and well-being. When assessing the degree of pain, almost half of the patients (48.73%) rated their pain by VAS as moderate. Moreover, most of the respondents experienced a “significant” (46.51%) or “moderate” (34.29%) decrease in social activity due to pain syndrome associated with osteoporosis. In connection with this, 44.51% rated their satisfaction with their lives as “average degree of satisfaction”.When analyzing the quality-of-life indicators according to the SF-36 scales, we determined that the mental component of health predominates for women (The Short Form-36: MH=68,6±3,45 (Men: MH=48,5±2,85)). In men, high quantitative values of the scales “physical” and “role physical functioning” (The Short Form-36: PF=62,5±3,33; RP=58,4±3,81) indicate a more pronounced nature of changes in somatic status, which has a significant impact on the quality-of-life. The intensity of pain was perceived to be higher by men (The Short Form-36: BP=75,6±4,06) than by women (The Short Form-36: BP=35,7±1,86). This confirms that osteoporosis and its complications negatively affect the human psyche and can significantly worsen the quality-of-life.Conclusion:Analysis of quality-of-life indicators using the SF-36, HRQOL method contributes to a more correct choice of effective strategy for specialized medical care and rehabilitation for patients with osteoporosis. This choice should be developed individually, taking into account the age, gender characteristics, the severity of structural and functional disorders and the psychological state of the patient. It must also take into account the presence and severity of concomitant diseases, which will require additional research and discussion at different levels of the organization of medical care.Disclosure of Interests:None declared

2020 ◽  
pp. 33-38
Author(s):  
E. Yu. Gan ◽  
L. P. Evstigneeva

Purpose of the study. Assessing the association between the life quality of patients with Sjogren’s Disease and ongoing therapy with various disease-modifying antirheumatic drugs.Material and methods. The study was conducted on the basis of the regional rheumatology center of the consultative diagnostic clinic of the Sverdlovsk Regional Clinical Hospital No. 1. This work is based on the results of a simultaneous study of 74 patients with primary Sjogren’s Disease (SD), distributed in three comparison groups receiving various disease-modifying antirheumatic drugs chlorambucil, methotrexate and hydroxychloroquine. The diagnosis of SD was carried out according to European-American criteria AECGC (2002) [18]. In order to analyze the quality of life of patients with SD, the 36-Item Short Form Health Survey (SF‑36) was used. Statistical data processing was carried out using Statistica 7.0 program.Results. Assessment of the quality of life of patients with SD, which is an integrative criterion of human health and well-being, revealed the absence of statistically significant differences (p > 0.05) on eight scales and two health components of the SF‑36 questionnaire in the analyzed groups that differ in the treatment of disease-modifying antirheumatic drugs chlorambucil, methotrexate and hydroxychloroquine.Conclusions. The obtained data indicate an equivalent quality of life in SD patients treated with different disease-modifying antirheumatic drugs methotrexate, chlorambucil and hydroxychloroquine, and therefore hydroxychloroquine can be considered as an alternative basic therapy in patients with SD with certain limitations and contraindications methotrexate and chlorambucil.


2011 ◽  
Vol 18 (2) ◽  
pp. 145-150 ◽  
Author(s):  
Maíra de Menezes Franco ◽  
Flaviane de Oliveira Souza ◽  
Elaine Cristine Lemes Mateus de Vasconcelos ◽  
Maurício Mesquita Sabino de Freitas ◽  
Cristine Homsi Jorge Ferreira

Trata-se de um ensaio clínico prospectivo comparativo que objetivou comparar os efeitos do tratamento com eletroestimulação transvaginal (ET) e do nervo tibial (ENT) sobre a qualidade de vida (QV) e queixas de perda urinária em mulheres com bexiga hiperativa. Participaram 42 pacientes com bexiga hiperativa ou incontinência urinária (IU) mista e foram divididas para tratamento com ET ou ENT. A QV foi avaliada pelo questionário de QV genérico, o Medical Outcomes Study Short Form 36 (SF-36) e um questionário específico para IU, o Incontinence Quality of Life Instrument (I-QOL). Os relatos de perdas urinárias e incômodos ocasionados foram avaliados, respectivamente, por meio do diário miccional de 24 horas e Escala Visual Analógica (EVA). O tratamento foi realizado uma vez por semana, totalizando doze semanas. O grupo da ENT teve melhora significativa em três domínios do I-QOL, na EVA, que avaliou o grau de incômodo causado pela IU e em quatro aspectos do diário miccional. No grupo de ET houve melhora significativa de dois domínios do SF-36, três domínios do I-QOL, na EVA e em quatro aspectos do diário. Houve melhora da QV em ambos os grupos, assim como uma diminuição das queixas de perda urinária, entretanto, o grupo que recebeu ET obteve melhora nos escores em dois domínios do questionário de QV genérico após o tratamento, que teve limitação por aspectos físicos e limitação por aspectos emocionais. O que não ocorreu com o grupo de ENT.


2020 ◽  
Vol 8 (2) ◽  
Author(s):  
Prachita P. Walankar ◽  
Vrushali P. Panhale ◽  
Manali M. Patil

Chronic shoulder pain is a complex and multidimensional phenomenon with multiple causative factors involved in its perpetuation. Alteration of central nervous system processing along with the central sensitization is a predominant feature in chronic pain. Reduction in physical function has an impact on the psychological well-being of an individual. The aim of the study was to compare pain, kinesiophobia, catastrophizing, disability and quality of life in chronic shoulder pain patients with and without central sensitization. Eighty chronic unilateral shoulder pain patients in the age group of 40 to 60 years were recruited. Of them, 38 were chronic shoulder pain with central sensitization and 42 without central sensitization, classified on the basis of central sensitization inventory. Pain catastrophizing was measured using the pain catastrophizing scale, kinesiophobia using Tampa scale of kinesiophobia, disability using Shoulder pain and disability index and quality of life using 36-Item Short Form Health Survey questionnaire was evaluated in both the groups. Increased pain catastrophizing (p=0.000), kinesiophobia (p=0.000) and disability (p=0.000) was observed in centrally sensitized chronic shoulder pain patients. Also, physical component summary (p=0.000) and mental component summary (p=0.000) of SF-36 quality of life were reduced in chronic shoulder pain with central sensitization as compared to without central sensitization. Hence, these components should be included during assessment which will provide a holistic and multimodal approach towards the understanding, planning and management of chronic shoulder pain patients.


2000 ◽  
Vol 80 (10) ◽  
pp. 986-995 ◽  
Author(s):  
Pat G Camp ◽  
Jessica Appleton ◽  
W Darlene Reid

Abstract Background and Purpose. The purpose of this study was to use quantitative and qualitative research methods to evaluate quality-of-life (QOL) changes in patients with chronic obstructive pulmonary disease (COPD) after pulmonary rehabilitation. Subjects. Twenty-nine individuals with COPD (18 women and 11 men), with a mean age of 69 years (SD=8.6, range=53–92), participated. Methods. Subjects were assessed before and after a 5-week control phase and after a 5-week rehabilitation phase using the Chronic Respiratory Questionnaire (CRQ), the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36), and spirometry. Our qualitative research was based on a subsample of 7 subjects who were interviewed after pulmonary rehabilitation. Results. Pulmonary rehabilitation improved QOL, as demonstrated by increases of 22% and 14% in the physical function categories of the CRQ and the SF-36, respectively, and by an increase of 10% in the CRQ's emotional function category. The qualitative data indicated how pulmonary rehabilitation influenced QOL. Conclusion and Discussion. The use of both quantitative and qualitative methods illustrated the nature of improvement in QOL after pulmonary rehabilitation. Improved physical function, less dyspnea, and a heightened sense of control over the subjects' COPD resulted in increased confidence and improved emotional well-being.


Blood ◽  
2002 ◽  
Vol 99 (6) ◽  
pp. 1995-2001 ◽  
Author(s):  
Mina Nishimori ◽  
Yoshitsugu Yamada ◽  
Keiko Hoshi ◽  
Yuichi Akiyama ◽  
Yasutaka Hoshi ◽  
...  

Abstract To promote bone marrow donation, both the safety and well-being of healthy unrelated volunteer donors must be protected. This prospective cohort study evaluated donors' health-related quality of life (HRQOL) and identified factors associated with it. Using the Medical Outcomes Study Short Form 36 Health Survey (SF-36) before bone marrow harvesting (BMH), and again 1 week and 3 months after the donors' discharge, we evaluated HRQOL of 565 donors (329 men, 236 women) registered with the Japan Marrow Donor Program (JMDP). We also examined the data routinely collected by the JMDP, such as BMH-related problems and other demographic and medical variables, to determine whether such data could be used to predict donors' HRQOL after discharge. Mean scores of all pre-BMH SF-36 subscales showed better functioning than the national norm. One week after discharge, mean scores on physical functioning (PF) and role-physical (RP) subscales, indicative of physical states, and bodily pain (BP) were approximately 1 SD lower than the national norm; however, mental health (MH) and general health perception (GH) remained above normal; the most frequent BMH-related problems were pain at the donation site and lower back pain, which were associated with lower PF, RP, and BP scores. Female gender and duration of procedure predicted lower PF, RP, and BP. Three months after discharge, mean scores of all SF-36 subscales had returned to baseline levels. These data show that the adverse effects of BMH on donors' HRQOL are transient and can be minimized by better management of pain.


2018 ◽  
Vol 1 (3) ◽  
pp. 177-181
Author(s):  
Agus Triyono ◽  
Widhi Astana ◽  
Fajar Novianto

Diabetes mellitus (DM) merupakan penyakit degenerative dengan murbiditas dan mortalitas yang terus meningkat. Herbal medicine telah banyak digunakan untuk mengontrol kadar glukosa darah (KGD) pasien DM. Penelitian ini bertujuan untuk menganalisis efek penggunaan ramuan jamu hiperglikemia terhadap kualitas hidup atau quality of life (QoL) pasien DM. Penelitian ini merupakan studi kohort dengan menggunakan kuesioner Short Form-36 (SF-36) sebagai alat pengukuran kualitas hidup 40 subjek penelitian dengan KGD sewaktu 200 – 300 mg/dl. Pasien diberi ramuan jamu temulawak ,kunyit, dan meniran tiga kali sehari selama 56 hari. Kualitas hidup subjek diukur pada hari ke 0, 28, dan 56. Pengaruh penggunaan jamu terhadap QoL dianalisis menggunakan uji t berpasangan.Sebanyak 58% dari subjek penelitian adalah perempuan. Hasil penelitian membuktikan terdapat perbedaan yang signifikan antara QoL sebelum dan setelah pemberian jamu selama 56 hari, (p=<0,05). Ramuan jamu batang brotowali, herba sambiloto, rimpang temulawak, rimpang kunyit, dan herba meniran dapat meningkatkan QoL pasien DM.   Diabetes mellitus (DM) is a degenerative disease with increased morbidity and mortality. Herbal medicine has been widely used to control blood glucose levels in DM patients. This study aimed to analyze the effect of consumehyperglycemic jamu formula on quality of life (QoL) in DM patients. This study was a cohort study using a Short Form-36 (SF-36) questionnaire as a quality of life measurement tool of 40 subjects with blood gluces levels at 200 - 300 mg / dl. The patient received a jamu fomula of ginger, turmeric, and meniran three times a day for 56 days. The quality of life of the subjects was measured on days 0, 28 and 56. The effect of the admintration of jamu on QoL was analyzed using paired t test. A total of 58% of the research subjects were women.  The results showed that there were significant differences of QoL before and after administration of jamu for 56 days (p = <0.05). Jamu formlua of brotowali stems, bitter herbs, curcuma rhizomes, turmeric rhizomes, and meniran herbs can increase the QoL of DM patients


2013 ◽  
Author(s):  
Αθανασία Παπαθανασίου

Σκοπός της έρευναςΗ εκτίμηση της ποιότητας ζωής των ασθενών με ΣΔ στην ΠρωτοβάθμιαΦροντίδα Υγείας στην Ελλάδα και η συγκριτική της μελέτη με την ποιότητα ζωήςτων ασθενών ενός εξειδικευμένου διαβητολογικού κέντρου.Πληθυσμός μελέτηςΗ μελέτη εφαρμόσθηκε στους ασθενείς του Κέντρο Υγείας Στυλίδας στονομό Φθιώτιδας και στους ασθενείς του διαβητολογικού κέντρου στο ΤζάνειοΝοσοκομείο του Πειραιά.Στη μελέτη περιλαμβάνονται ασθενείς με σακχαρώδη διαβήτη τύπου 2που παρακολοθούνται τακτικά στα παραπάνω κέντρα. Οι 818 πρώτοι ασθενείςπου πληρούσαν τα παραπάνω κριτήρια και προσήλθαν στα παραπάνω κέντρα από τον Δεκέμβριο του 2006 αποτελούν τον πληθυσμό της μελέτης.ΜέθοδοιΜετά από μία συστηματική αναζήτηση στη διεθνή και ελληνικήβιβλιογραφία για τον εντοπισμό εργαλείων που εκτιμούν τη σχετιζόμενη με τοσακχαρώδη διαβήτη ποιότητα ζωής στην Ελλάδα και τη διαπίστωση της έλλειψηςμιας ειδικής κλίμακας στη χώρα μας, η κλίμακα PAID μεταφράστηκε καισταθμίστηκε σύμφωνα με τις αρχές του Medical Outcomes Trust Bulletin 1997.Στη μελέτη χρησιμοποιήθηκαν οι εξής κλίμακες: Short Form- 36 version 2(SF-36 v2), Problem Areas In Diabetes (PAID) Scale και Diabetes TreatmentSatisfaction Questionnaire status version(DTSQ-s).Για την καταχώρηση και ανάλυση των δεδομένων δημιουργήθηκε έναηλεκτρονικό σύστημα καταχώρησης ασθενών χρησιμοποιώντας FileMaker Pro από τον Δεκέμβριο του 2006 αποτελούν τον πληθυσμό της μελέτης.ΜέθοδοιΜετά από μία συστηματική αναζήτηση στη διεθνή και ελληνικήβιβλιογραφία για τον εντοπισμό εργαλείων που εκτιμούν τη σχετιζόμενη με τοσακχαρώδη διαβήτη ποιότητα ζωής στην Ελλάδα και τη διαπίστωση της έλλειψηςμιας ειδικής κλίμακας στη χώρα μας, η κλίμακα PAID μεταφράστηκε καισταθμίστηκε σύμφωνα με τις αρχές του Medical Outcomes Trust Bulletin 1997.Στη μελέτη χρησιμοποιήθηκαν οι εξής κλίμακες: Short Form- 36 version 2(SF-36 v2), Problem Areas In Diabetes (PAID) Scale και Diabetes TreatmentSatisfaction Questionnaire status version(DTSQ-s).Για την καταχώρηση και ανάλυση των δεδομένων δημιουργήθηκε έναηλεκτρονικό σύστημα καταχώρησης ασθενών χρησιμοποιώντας FileMaker Pro κέντρου υγείας Στυλίδας και 39.67 (±16.29) για τους ασθενείς του ΤζάνειουΝοσοκομείου του Πειραιά. Σχετικά με τα αποτελέσματα της κλίμακας DTSQ-s, τοτελικό αποτέλεσμα ήταν 26.81 (±8.2) για τους ασθενείς του κέντρου υγείαςΣτυλίδας και 22.13 (±8.9) για τους ασθενείς του Τζάνειου Νοσοκομείου τουΠειραιά (p< 0.0001).ΣυμπεράσματαΈνα σημαντικό αποτέλεσμα της μελέτης είναι η μετάφραση και στάθμιση στηνελληνική γλώσσα της κλίμακας Problem Areas In Diabetes (PAID) Scale, ενόςσημαντικού και πολυχρησιμοποιημένου στις διεθνείς μελέτες εργαλείου, πουαξιολογεί τις συναισθηματικές και διαπροσωπικές δυσκολίες των ασθενών μεΣΔ, που σχετίζονται με τη δίαιτα ή τη σχέση του με το γιατρό. Από τον πληθυσμό της μελέτης προέκυψε ότι οι ασθενείς πουπαρακολουθούνται στο διαβητολογικό τακτικό ιατρείο του Τζάνειου ΝοσοκομείουΠειραιά (αστικός πληθυσμός) είχαν συστηματικά χαμηλότερα αποτελέσματα σε όλες τις υποκατηγορίες της κλίμακας Short Form-36 version 2 (MCS και PCSscores) καθώς και στις κλίμακες PAID και DTSQ σε σχέση με τον πληθυσμό τουΚέντρου Υγείας Στυλίδας (αγροτικός πληθυσμός).Τα ευρήματα αυτής της μελέτης θα μπορούσαν να αξιοποιηθούν στηνπρακτική διαχείριση των ασθενών με σακχαρώδη διαβήτη, αλλά και στοναποτελεσματικό σχεδιασμό των προσφερόμενων υπηρεσιών υγείας.


2020 ◽  
Vol 34 ◽  
pp. 205873842093462
Author(s):  
Angela Rizzi ◽  
Alessia Di Rienzo ◽  
Alessandro Buonomo ◽  
Arianna Aruanno ◽  
Valentina Carusi ◽  
...  

Nickel (Ni) oral hyposensitization treatment (NiOHT) is an effective management approach for Ni allergy. No health-related quality of life (HRQoL) data exist for the pre- and post-treatment with NiOHT in systemic nickel allergy syndrome (SNAS). The aims of this study were (a) to explore HRQoL in SNAS patients, (b) to assess changes of HRQoL after 1 year of NiOHT; (c) to evaluate psychological status of patients. SNAS patients completed the Short-Form 36-Item Health Survey and Psychological General Well-Being Index before and 1 week after the end of NiOHT. Moreover, psychological state was assessed with the Minnesota Multiphasic Personality Inventory (MMPI-2). A total of 52 patients self-reported pre- and post-treatment questionnaires. HRQoL was poor at baseline. After 1 year of NiOHT, all outcome measure scores improved by about 20% with respect to baseline data ( P < 0.01 for all indices, except depressed mood). Finally, 33 patients performed the MMPI-2. High rates for hypochondriasis and depression were noted. Furthermore, most of the patients had high scores for anxiety, depression, and health concerns. This is the first study showing that NiOHT improves HRQoL of SNAS patients, which can be considered a “personalized medicine” approach.


2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 19657-19657
Author(s):  
E. L. Morgenfeld ◽  
B. Rolnik ◽  
L. Cassab ◽  
D. Gercovich ◽  
F. Negro ◽  
...  

19657 Background: Hormonotherapy (H) is the most widely used treatment against breast cancer (BC). The aim of this study is a prospective evaluation with an enriched the SF-36 questionnaire, of the QOL of BC patients (pt) treated with H at the IOHM. Specific questions regarding menopausal symptoms and body weight were added. Methods: Between Aug 2005 and Nov 2006, all pt that were undergoing H, were requested to fill out a SF-36 self-evaluation form. The SF-36 is a multi-purpose, short-form health survey, with 36 questions about functional health and well-being. The answers were tabulated. The pre-treatment and post-treatment body weight of each pt was registered. Results: Three Hundred and Twenty-six pt were invited to participate, and all of them accepted, and signed a consent form. Characteristics of the population: Diagnosis: DCIS: 36 pt; LCIS: 5 pt; IDC 250 pt; ILC: 35 pt. All cases expressed hormonal receptors. The H was adjuvant in 254 pt (78%) mostly treated with T and palliative in 72 pt (22%) mostly treated with AI. Median age was 62 years, however 63 pt (19%) were pre-menopausal. The median time under treatment was 33 months (range 1–71 m). The pt reported: General evaluation of Quality of life: Very good or excellent: 154 pt (47%) , Good: 134 pt (41%), Poor: 34 pt (11%). Severe limitations for demanding physical activities: 43 pt (13 %). A reduction of time spent on the job: 66 pt (22%). Severe pain during the last four weeks prior to answering the questionnaire: 24 pt (8 %). Weight increase perception: 153 pt (47%). Actual increase of weight: 192 pt (60%) (Median: 4 kg). Menopausal symptoms: Daily Hot Flushes: 132 pt (40%). Vaginal discharge 110 pt (33%) Decrease of libido: 98 pt (30%), Vaginal dryness 76 pt (23%), Nightly sweats: 40 pt (12%). Sixty pt (18%) suffered from and received treatment for menopausal symptoms. Conclusions: 1) The SF-36 is a useful tool to measure the BC patients’ quality of life 2) Although in our cohort most of the patients (88,3%) rated their general QOL as “good to very good”, a third of the pt presented severe menopausal symptoms, and 18% received non hormonal medication for symptoms relief 3) Sixty percent of the pt had a median body weight gain of 4 Kg. No significant financial relationships to disclose.


2016 ◽  
Vol 15 (4) ◽  
Author(s):  
Jeanette Janaina Jaber Lucato

Introdução: As disfunções causadas pela sepse são responsáveis pela alta mortalidade e por longos períodos de hospitalização. A análise da qualidade de vida vem sendo usada como medida relevante em pacientes sobreviventes à sepse, sepse grave e choque séptico. Objetivo: Verificar se existe na literatura um perfil ou padrão na Qualidade de Vida (QV) de pacientes sobreviventes a essa condição, delineado pela aplicação das escalas Short Form-36 (SF-36) e European Quality of Life-5 Dimensions (EQ-5D). Método: Revisão integrativa da literatura para avaliar a QV de pacientes sobreviventes a essa condição, do período 2003 até 2013. Resultados: A maioria dos estudos encontrou diminuição nas pontuações ou surgimentos de maiores problemas após a alta hospitalar, comparados com os pacientes que não desenvolveram sepse ou com a população em geral, e aumento da mortalidade ao longo do tempo. Conclusão: Não há um consenso entre as escalas aplicadas. Mais estudos que apliquem algum tipo de escala e/ou questionário de mensuração nesses pacientes são necessários.Palavras-chave: qualidade de vida, sepse, escala de avaliação.


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