scholarly journals 987 Emipediology and Morbidity of Late Preterm Neonates in Correlation with Maternal Risk Factors in Hessen, Germany

2012 ◽  
Vol 97 (Suppl 2) ◽  
pp. A282-A282
Author(s):  
D. Faas ◽  
M. Vajz ◽  
U. Hennewig ◽  
B. Misselwitz ◽  
F. Oehmke ◽  
...  
Keyword(s):  
Risk Factors ◽  
Late Preterm ◽  
Preterm Neonates ◽  
Maternal Risk Factors ◽  
Maternal Risk

scholarly journals Maternal risk factors and early neonatal outcome among late preterm and term neonates in a neonatal intensive care unit in Punjab, India

2018 ◽  
Vol 5 (2) ◽  
pp. 612
Author(s):  
Kambiakdik T. ◽  
Anish D. Leelalanslat ◽  
Inderpreet Sohi ◽  
Varughese P. Varkey
Keyword(s):  
Risk Factors ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Late Preterm ◽  
Preterm Neonates ◽  
Maternal Risk Factors ◽  
Term Neonates ◽  
Maternal Risk

Background: Late preterm neonates (34 to 36 weeks 6/7 days) were considered as ‘near term’ as they appeared apparently mature and comparable to term neonates. Many studies have now reported significantly higher rates of morbidity and mortality among this group of neonates. This study aims to evaluate the maternal risk factors associated with and short-term outcome of late preterm neonates compared to term neonates.Methods: A Retrospective cohort study was conducted in the Neonatal Intensive Care Unit of a tertiary care teaching hospital. All intramural late preterm neonates with gestational age of 34-36 weeks born during the study period were enrolled. The control group included term neonates (37-42 weeks) born during the study period. Data regarding the maternal risk factors and neonatal outcomes for both the late preterm and term neonates were collected from records maintained in the NICU. Results: There were 3275 deliveries during the study period, of which 2447 (74.8%) were term. Among the 828 preterm neonates, 500 (60.4%) were late preterms. The maternal risk factors significantly associated with late preterm neonates were PIH, eclampsia, APH, multiple gestation, PROM, oligohydramnios and abnormal dopplers. Incidence of Respiratory distress syndrome (RDS), sepsis and hypoglycemia were higher among the late preterm group with an odd’s ratio of 56.01, 9.9 and 7.8 respectively. Incidence of hypocalcemia, seizures and Persistent Pulmonary Hypertension (PPHN) were also higher among this group. There was no statistically significant difference in mortality among the two groups.Conclusions: Late preterm neonates have a significantly higher neonatal morbidity compared to term neonates.

scholarly journals Maternal risk factors and immediate outcome of late preterms

2019 ◽  
Vol 6 (5) ◽  
pp. 1845
Author(s):  
Sahana Giliyaru ◽  
Sahaya Nirmala S. ◽  
Adarsh E.
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Gestational Age ◽  
Mode Of Delivery ◽  
Late Preterm ◽  
Close Monitoring ◽  
Maternal Risk Factors ◽  
Maternal Risk ◽  
Preterm Babies ◽  
Nicu Admission

Background: This study was conducted to analyse the immediate outcome of late preterm babies and also to evaluate the various maternal risk factors in these babies so that close monitoring of these babies for the complications is done and immediate problems can be addressed.Methods: Prospective observational study done in level 3 NICU setting for 6 months. All babies born between 34-36/7 weeks are included in the study and they constitute the cases. Term (above 36 weeks 6 days gestation) newborns babies born during the study period are controls. Maternal history is taken in detail. Risk factors during pregnancy including maternal age, gravida, mode of delivery, medical conditions and birth details. Baby details like gestational age, sex, birth weight, and neonatal morbidities are recorded. The babies are either shifted to NICU or to mother’s side based depending on the baby’s condition. All of them are followed up till discharge.Results: 89 late preterm babies born in the hospital during the study period are included in the study. Out of 89 babies 45are females constituting 50.6% and 44are male babies constituting 49.4%. 20 (22.5%) babies had gestational age between 34-35 weeks.29 babies (32.5 %) had gestational age between 35-36 weeks and 40 babies (45%) are between 36-37 weeks of gestation. 47 babies (52.9%) have birth weight between 1.5-2.49 kg.42 babies (47.1%) have birth weight between 2.5-3.5 kg. The number of babies born by LSCS were 48 (54%) and 41 babies 46% are born through vaginal route.42 babies constituting 48.3% are appropriate for gestational age and 43 babies (49.4%) are small for gestationalage.34 (39.1%) babies required NICU admission and 55 (60.9%) babies did not require NICU admission. Among the maternal risk factors PIH was the commonest risk factor in 22babies (24.7 %), followed by PROM13 (14.6 %), oligohydramnios 6 (6.7 %) ,twin gestation 6 (6.7 %), MSAF 3 (3.4%), IDM 3 (3.4%), Antepartum hemorrhage 3 (3.4%), eclampsia 1 (1.1%) and maternal cardiac disease 1.1%. Neonatal morbidities are 25 late preterm babies had jaundice (28.7%) followed by RDS in 15 (17.2%), sepsis in 9 (10.3%), NEC 2 (2.3%), Hypoglycemia 5 (5.6%) late preterm babies required ventilation/ CPAP constituting 5.7%. Surfactant was used in 2 late preterm babies 2.3%. 87 babies (97.8%) got discharged and mortality is 2.2%.Conclusions: Late prematurity is associated with significant neonatal morbidity.

scholarly journals Morbidity and mortality profile of preterm neonates admitted in neonatal intensive care unit of a tertiary care centre in Western Uttar Pradesh, India

2019 ◽  
Vol 6 (5) ◽  
pp. 1859
Author(s):  
Najia Hassan ◽  
Sujaya Mukhopadhyay ◽  
Sneha Mohan
Keyword(s):  
Risk Factors ◽  
Neonatal Intensive Care ◽  
Tertiary Care ◽  
Preterm Neonates ◽  
Pregnancy Induced Hypertension ◽  
Care Centre ◽  
Maternal Risk Factors ◽  
Tertiary Care Centre ◽  
Maternal Risk ◽  
Induced Hypertension

Background: Preterm birth is a major cause of mortality and morbidity for newborns. Complications of prematurity are becoming more common as more survivors are spending time in Neonatal intensive care unit.Methods: A retrospective hospital based clinical observational study was conducted in NICU in Sharda hospital, a tertiary care centre in Greater Noida. Data regarding neonates′ age, sex, clinical presentation, maternal risk factors, complications and outcome were recorded.Results: A total of 133 preterm neonates were enrolled in the study. Maternal risk factors like Pregnancy induced hypertension (PIH) was seen in 19.5% cases, Urinary tract infection in 15% and Antepartum haemorrhage in 14.2% cases. Among the complications of prematurity, RDS was noted in 38.3% cases, Hyperbilirubinemia in 16.5% and feed intolerance in 15% cases. Sepsis was present in 3% of the preterm. Mortality rate was 7.5%. Most common cause of death was RDS.Conclusions: Pregnancy induced hypertension and Antepartum haemorrhage were important maternal risk factors for prematurity. Respiratory distress syndrome and perinatal asphyxia were the important causes of mortality in the present study.

Impact of Prematurity on the Buccal Epithelial Cells of the Neonates via Wnt/Beta-Catenin Signaling Pathway and Apoptosis

2021 ◽  
Author(s):  
Hanife Guler Donmez ◽  
Hasan Tolga Celik ◽  
Gozdem Kayki ◽  
Atakan Tanacan ◽  
Murat Cagan ◽  
...  
Keyword(s):  
Risk Factors ◽  
Signaling Pathway ◽  
Obstetric Complications ◽  
Preterm Neonates ◽  
Beta Catenin ◽  
Maternal Risk Factors ◽  
Buccal Cells ◽  
Maternal Risk ◽  
Neonatal Complications ◽  
The Impact

Objective Understanding the reflections of prematurity is necessary for the management of neonatal complications. We focused on the impact of prematurity and related “maternal risk factors/obstetric complications” on buccal cells of the neonates via evaluation of the Wnt/β-catenin signaling pathway and apoptosis. Study Design This study consisted of “early preterm neonates (EPN) (≤34th gestational week [gw]) (n = 36),” “late preterm neonates (LPN) (34th– < 37th gw) (n = 46),” and “term neonates (control) (≥37th gw) (n = 56).” Cohort was also subclassified according to the presence of maternal risk factors, obstetric complications, and neonatal complications. Wnt/β-catenin signaling and caspase-3 activation pathways were studied immunocytochemically. Results Wnt/β-catenin signaling positivity was statistically more frequent at buccal smears of the EPN and LPN groups compared with controls (p < 0.001). The cutoff for gestational age at delivery in receiver operating characteristic curve with the best balance of sensitivity (67.4%) and specificity (67.3%) was 35.8th gw for determining the reduction of Wnt/β-catenin signaling positivity (p < 0.001). The study demonstrated that obstetric complications significantly affected the activity of signaling, while maternal risk factors do not have any effect on Wnt/β-catenin signaling pathway (p = 0.003 and p = 0.828, respectively). This study also demonstrated a significant relationship between Wnt/β-catenin signaling pathway and the presence of neonatal complications (p = 0.015). Conclusion Dynamic characteristics of buccal cells are influenced by prematurity and related obstetric and neonatal problems. Buccal smear is a good tool to investigate the impact of prematurity and obstetric problems on perinatal outcome. Key Points

scholarly journals CLINICAL PREDICTION OF EARLY ONSET SEPSIS IN PRETERM NEONATES

2020 ◽  
Vol 73 (10) ◽  
pp. 2219-2223
Author(s):  
Valeriy Pokhylko ◽  
Yuliia Cherniavska ◽  
Nataliia Adamchuk ◽  
Svitlana Tsvirenko ◽  
Yuliia Klimchuk
Keyword(s):  
Risk Factors ◽  
Predictive Value ◽  
Early Onset ◽  
Prognostic Model ◽  
Preterm Neonates ◽  
Monocyte Count ◽  
Maternal Risk Factors ◽  
Maternal Risk ◽  
Early Onset Sepsis ◽  
Diagnostic Characteristics

The aim of the study was to analyze and identify risk factors for the development of early onset sepsis in preterm neonates and to develop a clinical prognostic model. Materials and methods: A retrospective cohort study included 152 newborns with birth weight from 1000 to 2500 g, who were treated in the neonatal intensive care units of medical institutions in the Poltava region. Among 152 children, 121 had clinical and laboratory symptoms of infection, which were regarded as manifestations of early onset sepsis, the rest of the children (n = 31) had no manifestations of infection. Results: According to the results of multiple stepwise logistic regression analysis, the predictive model has been developed. It included gestational age, visual changes of placenta, Apgar score at the 1st minute, the level of monocytes more than 6.5%, the history of abortions and premature rupture of membranes. The diagnostic characteristics of the developed model had high: sensitivity – 82.2%, specificity – 93.55%, positive predictive value – 97.98%, negative predictive value – 58%. Conclusions: The prognostic model developed by us, which showed high diagnostic characteristics, includes information on maternal risk factors, the state of the newborn immediately after birth, and biomarkers of infection (C-reactive protein and monocyte count). Therefore, we believe that when interpreting biomarkers, the decision to prescribe antibiotics should be based on the presence of maternal risk factors and clinical symptoms of infection in the prematurely born child, which may be nonspecific

Maternal risk factors and obstetric complications in late preterm prematurity

2014 ◽  
Vol 179 ◽  
pp. 105-109 ◽  
Author(s):  
Cristina C. Trilla ◽  
Maria C. Medina ◽  
Gemma Ginovart ◽  
Jocelyn Betancourt ◽  
Josep A. Armengol ◽  
...  
Keyword(s):  
Risk Factors ◽  
Obstetric Complications ◽  
Late Preterm ◽  
Maternal Risk Factors ◽  
Maternal Risk

scholarly journals A study of short term outcome of late preterm babies

2017 ◽  
Vol 4 (3) ◽  
pp. 858
Author(s):  
Selvan Tamil ◽  
Saravanan P. ◽  
Nagaraj M. S. ◽  
Mrigendra Nath Tudu
Keyword(s):  
Risk Factors ◽  
Late Preterm ◽  
Maternal Risk Factors ◽  
Short Term ◽  
Term Outcome ◽  
Maternal Risk ◽  
Short Term Outcome ◽  
Preterm Babies ◽  
The Common ◽  
And Control

Background: Late preterm babies born between 34 to <37 weeks of gestation are associated with adverse short term and long term outcomes and an increased burden on health care. Aim was to study the short term outcome of late preterm babies in comparison with term babies and to study the maternal risk factors involved in late preterm.Methods: Prospective and descriptive study was conducted on the late preterm babies born at SIMS & RC over a period of 15 months from October 2015 to December 2016. Cases included were late preterm newborns and control was term newborns.Results: Among late preterm babies, the common maternal risk factors observed was PIH in 35.3% (40/113), antepartum haemorrhage in 20.3% (23/113) and PPROM in 19.4% (22/113) of the cases. Based on gestational age, majority of them were between 35≤36 weeks in 38.9% (44/113). Based on birth weight, most of them were between 1.5-2.5 kg in 85.8% (97/113). Among gender majority of them were males in 56.6% (64/113) of the cases. Late preterm babies had more morbidities and mortality compared to term babies. The common morbidities observed were jaundice in 63.7% (72/113), feed intolerance in 28.3% (32/113), hypoglycemia in 27.4% (31/113) and sepsis in 22.1% (25/113) of the cases when compared to term babies jaundice were noted in 62% (1228/1978), sepsis in 5.7% (113/1978), hypoglycaemia in 3.4% (68/1978), respiratory distress in 3.1% (63/1978) of the cases respectively. The late preterm mortality was 1.7% (2/113) compared term mortality of 0.45% (9/1978). Overall late preterm mortality rate was 0.86% (2/2311) compared to term which was 3.89%(9/2311) of the total live births.Conclusions: This study shows morbidity and mortality was high in late preterm babies compared to term babies with significant maternal risk factors. 

A Study on Maternal Risk Factors and Preterm Neonates

2017 ◽  
Vol 5 (3) ◽  
pp. 188-191
Author(s):  
Divyarani D.C ◽  
◽  
Goudappa R. Patil ◽  
Keyword(s):  
Risk Factors ◽  
Preterm Neonates ◽  
Maternal Risk Factors ◽  
Maternal Risk
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