scholarly journals Age-related blood changes in hip osteoarthritis patients: a possible indicator of bone quality.

1982 ◽  
Vol 41 (2) ◽  
pp. 215-216 ◽  
Author(s):  
C H Rapin ◽  
R Lagier
Keyword(s):  
Bone Quality ◽  
Hip Osteoarthritis ◽  
Age Related

scholarly journals Age-related blood changes in hip osteoarthritis patients: a possible indicator of bone quality.

1983 ◽  
Vol 42 (1) ◽  
pp. 112-113 ◽  
Author(s):  
P Geusens ◽  
J Dequeker ◽  
A Verstraeten
Keyword(s):  
Bone Quality ◽  
Hip Osteoarthritis ◽  
Age Related

Clinical and histomorphometrical assessment of bone quality in hip osteoarthritis and osteoporosis

2013 ◽  
Author(s):  
Maurizio Feola ◽  
Cecilia Rao ◽  
Monica Celi ◽  
Elena Gasbarra ◽  
Umberto Tarantino
Keyword(s):  
Bone Quality ◽  
Hip Osteoarthritis

Age-related Changes of Slow Resistance Training on Body Composition and Bone Quality in Women

2011 ◽  
Vol 43 (Suppl 1) ◽  
pp. 574-575
Author(s):  
Yasuo N. Kimura ◽  
Kazuko Ohki ◽  
Toshiaki Ezaki ◽  
Naoki Nakagawa ◽  
Takeshi Sato
Keyword(s):  
Body Composition ◽  
Resistance Training ◽  
Bone Quality ◽  
Age Related ◽  
Age Related Changes

Differential characteristics of bone quality and bone turnover biochemical markers in patients with hip Fragility Fractures and Hip Osteoarthritis: results of a clinical pilot study

2011 ◽  
Vol 23 (2) ◽  
pp. 99-105 ◽  
Author(s):  
Giuseppina Resmini ◽  
Silvia Migliaccio ◽  
Luca Dalle Carbonare ◽  
Umberto Sala ◽  
Marina Brama ◽  
...  
Keyword(s):  
Pilot Study ◽  
Bone Turnover ◽  
Bone Quality ◽  
Biochemical Markers ◽  
Hip Osteoarthritis ◽  
Fragility Fractures

Probabilistic Prediction of Microdamage Progression in Bone

2008 ◽  
Author(s):  
X. Neil Dong ◽  
Daniel M. Sparkman ◽  
Huijie Leng ◽  
Harry R. Millwater ◽  
Xiaodu Wang
Keyword(s):  
Bone Quality ◽  
Elderly Population ◽  
Bone Fractures ◽  
The Elderly ◽  
Ultrastructural Level ◽  
Optical Microscope ◽  
Health Concern ◽  
Probabilistic Prediction ◽  
Major Health ◽  
Age Related

Age-related bone fractures are a major health concern to the elderly population. In addition to the loss of bone mass, the deterioration of bone quality is another major reason for such fractures. The decline of bone quality is manifested with the accumulation of microdamage in bone with age [1]. Two major types of microdamage have been observed in bone tissue: linear microcracks and diffuse damage [2]. Linear microcracks are individual cracks at a size of microns or larger and are usually visible under an optical microscope. On the other hand, diffuse damage is detectable only by staining and consists of an extensive network of fine, ultrastructural-level defects. The mechanisms for the formation of these two distinct types of microdamage in bone are still unclear. In this study, probabilistic finite element models of mineral-collagen composites were used to study the progression of microdamage in bone, thereby exploring the conditions under which linear microcracks and diffuse damage are produced in bone.

Variations in trabecular bone composition with anatomical site and age: potential implications for bone quality assessment

1997 ◽  
Vol 155 (3) ◽  
pp. 411-421 ◽  
Author(s):  
J Aerssens ◽  
S Boonen ◽  
J Joly ◽  
J Dequeker
Keyword(s):  
Lumbar Spine ◽  
Trabecular Bone ◽  
Bone Quality ◽  
Bone Matrix ◽  
Anatomical Site ◽  
Bone Composition ◽  
Age Related ◽  
Skeletal Site ◽  
Igf I ◽  
Age Range

Skeletal site-related differences in trabecular bone composition have been studied in autopsy samples from 63 individuals (age range 23-92 years). From each individual, bone samples were excised from the iliac crest, lumbar spine, femoral neck, and calcaneus. Samples were analyzed for their content of ash, calcium, collagen, extractable proteins, osteocalcin, and IGF-I. Significant differences were found between the skeletal sites, the lumbar spine being the least mineralized site and the femur the most. The femur and lumbar spine had a higher osteocalcin and IGF-I content compared with the other skeletal sites, suggesting a higher bone turnover rate. The intercorrelations between the anatomical sites were low for minerals and collagen but high for osteocalcin and IGF-I. The latter might indicate that the presence of these proteins in the bone matrix is mainly controlled by endocrine mechanisms which may influence the osteoblast function. Finally, regression analysis showed a significant age-related decrease of skeletal IGF-I at all sites examined. This finding supports the hypothesis of an IGF-I-mediated pathogenesis of senile osteoporosis. In summary, our data imply that a global assessment of skeletal function and bone quality, based upon analyses at one anatomical site, should be applied with caution.

Progressive Energy Dissipations of Human Cortical Bone in Compression

2008 ◽  
Author(s):  
Huijie Leng ◽  
Xuanliang Dong ◽  
Xiaodu Wang
Keyword(s):  
Energy Dissipation ◽  
Cortical Bone ◽  
Bone Quality ◽  
Bone Fracture ◽  
Maximum Stress ◽  
Factors Affecting ◽  
Age Related ◽  
Significant Burden ◽  
Underlying Mechanisms ◽  
Loading Modes

Bone fracture has imposed a significant burden on the health of society. The “bone quality” is used to refer to factors affecting bone fracture risk [1]. Energy dissipation till fracture, known as toughness, is a major measure of bone quality [2]. However, underlying mechanisms of energy dissipation in bone is still not clear. It has been well documented that the post-yield behavior of bone determines the major part of the toughness of bone [3, 4]. Therefore, it is important to study post-yield behaviors of human bone, especially the different pathways for energy dissipation, in order to better understand how age-related change affects bone quality. Bone behaves differently under different loading modes [5]. Different from loading in tension, after reaching the maximum stress, cortical bone in compression can continue to bear load till large deformation without brittle failure and dramatic reduction in elastic modulus [5, 6]. However, few studies of progression of post-yield behaviors of cortical bone in compression were reported in the literature.

Muscle size, neuromuscular activation, and rapid force characteristics in elderly men and women: effects of unilateral long-term disuse due to hip-osteoarthritis

2007 ◽  
Vol 102 (3) ◽  
pp. 942-948 ◽  
Author(s):  
C. Suetta ◽  
P. Aagaard ◽  
S. P. Magnusson ◽  
L. L. Andersen ◽  
S. Sipilä ◽  
...  
Keyword(s):  
Muscle Strength ◽  
Muscle Mass ◽  
Muscle Activation ◽  
Hip Osteoarthritis ◽  
Muscle Size ◽  
Elderly Men ◽  
Neuromuscular Activation ◽  
Emg Amplitude ◽  
Age Related

Substantial evidence exists for the age-related decline in muscle strength and neural function, but the effect of long-term disuse in the elderly is largely unexplored. The present study examined the effect of unilateral long-term limb disuse on maximal voluntary quadriceps contraction (MVC), lean quadriceps muscle cross-sectional area (LCSA), contractile rate of force development (RFD, Δforce/Δtime), impulse (∫force d t), muscle activation deficit (interpolated twitch technique), maximal neuromuscular activity [electromyogram (EMG)], and antagonist muscle coactivation in elderly men (M: 60–86 yr; n = 19) and women (W: 60–86 yr; n = 20) with unilateral chronic hip-osteoarthritis. Both sides were examined to compare the effect of long-term decreased activity on the affected (AF) leg with the unaffected (UN) side. AF had a significant lower MVC (W: 20%; M: 20%), LCSA (W: 8%; M: 10%), contractile RFD (W: 17–26%; M: 15–24%), impulse (W: 10–19%, M: 19–20%), maximal EMG amplitude (W: 22–25%, M: 22–28%), and an increased muscle activation deficit (−18%) compared with UN. Furthermore, women were less strong (AF: 40%; UN: 39%), had less muscle mass (AF: 33%; UN: 34%), and had a lower RFD (AF: 38–50%; UN: 41–48%) compared with men. Similarly, maximum EMG amplitude was smaller for both agonists (AF: 51–63%; UN: 35–61%) and antagonist (AF: 49–64%; UN: 36–56%) muscles in women compared with men. However, when MVC and RFD were normalized to LCSA, there were no differences between genders. The present data demonstrate that disuse leads to a marked loss of muscle strength and muscle mass in elderly individuals. Furthermore, the data indicate that neuromuscular activation and contractile RFD are more affected by long-term disuse than maximal muscle strength, which may increase the future risk for falls.

scholarly journals Age-related decrease in the activity of collagenase in the femoral head in patients with hip osteoarthritis

2006 ◽  
Vol 26 (2) ◽  
pp. 284-284
Author(s):  
M. Zgoda ◽  
L. Pączek ◽  
I. Bartłomiejczyk ◽  
J. Siemińska ◽  
D. Chmielewski ◽  
...  
Keyword(s):  
Femoral Head ◽  
Hip Osteoarthritis ◽  
Age Related
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